A quantitative method for the determination of bosutinib in human plasma using high-performance liquid chromatography and ultraviolet detection.

abstract：BACKGROUND:Multiple organ dysfunction syndromes (MODS) is reported as a leading cause of mortality in intensive care units. Recently, continuous blood purification (CBP) has been mostly applied for MODS treatment. Thus, the purpose of this study was to investigate the effects of CBP on plasma phospholipid level in pati...

journal_title：Journal of clinical laboratory analysis

authors： Wen W,Wang K,Jiang ZM,Zhang ZH,Zhou L

更新日期：2018-07-01 00:00:00

abstract：:Positive predictive values for the diagnosis of systemic lupus erythematosus (SLE) were determined for two antinative DNA assays: a Farr-type radioimmunoassay (RIA) and a solid-phase enzyme immunoassay (EIA). The study population consisted of all patients whose EIA anti-DNA results were positive (greater than 250 IU) ...

journal_title：Journal of clinical laboratory analysis

authors： Clough JD,Chang RK

更新日期：1989-01-01 00:00:00

abstract：:We have evaluated a new latex nephelometric test for the quantitation of myoglobin in human serum. The assay consists of incubating the diluted serum sample (20-fold) for 12 min at room temperature with latex particles covalently coated with anti-myoglobin antibodies and then quantifying the change of light-scatter pr...

journal_title：Journal of clinical laboratory analysis

authors： Borque L,Rus A,Ruiz R

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Liver biopsy is recommended in the majority of patients with chronic viral hepatitis for fibrosis evaluation. Because of the potential risks of liver biopsy, many studies related to non-invasive biomarkers of hepatic fibrosis have been performed. We aimed to assess the diagnostic value of serum biglycan as a...

journal_title：Journal of clinical laboratory analysis

authors： Ciftciler R,Ozenirler S,Yucel AA,Cengiz M,Erkan G,Buyukdemirci E,Sönmez C,Esendaglı GY

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Cell-free DNA (cfDNA) in the plasma of patients with both malignant and benign breast lesions was analyzed to determine whether the findings may have diagnostic and prognostic implications and to analyze the association between the levels of cfDNA and prognostic parameters. METHODS:Plasma samples were obtai...

journal_title：Journal of clinical laboratory analysis

authors： Hashad D,Sorour A,Ghazal A,Talaat I

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is an emerging problem all over the world. Because NAFLD and polycystic ovary syndrome (PCOS) are both closely related with insulin resistance, it would be necessary to determine the rate of presence of NAFLD in PCOS patients. So, this study aimed to investigate the u...

journal_title：Journal of clinical laboratory analysis

authors： Caner S,Altınbaş A,Saykı M,Büyükcam F,Yılmaz B,Çakal E,Çoban Ş,Delibaşı T

更新日期：2014-09-01 00:00:00

abstract：:The experimental and clinical effectiveness of nasal salmon calcitonin (SCT) for treatment of osteoporosis in humans has been well established, but none is known yet about the pharmacokinetic property in relation to therapeutic efficacy, especially when used in a therapeutic dose range. This preclinical study was desi...

journal_title：Journal of clinical laboratory analysis

authors： Nakamuta H,Kohno T,Ichikawa M,Hoshino T,Watabe K,Koida M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Identification of dermatophytes at the species level, relying on macro- and microscopic properties of the colonies is time-consuming, questioned in many circumstances, and requires considerable expertise. In this study, we examined the potency of a new genetic marker, β-tubulin (BT2) gene, for differentiatio...

journal_title：Journal of clinical laboratory analysis

authors： Abastabar M,Mirhendi H,Rezaei-Matehkolaei A,Shidfar MR,Kordbacheh P,Makimura K

更新日期：2014-03-01 00:00:00

abstract：INTRODUCTION:The pro- and anti-inflammatory cytokines play crucial role in the development and functions of placenta. Any changes in these cytokines may be associated with many pregnancy-related disorders like preeclampsia. Therefore, the present study is aimed to study the expression of pro-inflammatory (TNF-α, IL-6) ...

journal_title：Journal of clinical laboratory analysis

authors： Aggarwal R,Jain AK,Mittal P,Kohli M,Jawanjal P,Rath G

更新日期：2019-05-01 00:00:00

abstract：:A microparticle-enhanced nephelometric immunoassay was developed for lactoferrin quantitation in human milk. It is based on the nephelometric measurement of the light scattered during the competitive immuno-agglutination of a microparticle-lactoferrin conjugate with an antilactoferrin antiserum. This immunoassay is se...

journal_title：Journal of clinical laboratory analysis

authors： Cuillière ML,Montagne P,Molé C,Béné MC,Faure G

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Red cell distribution width (RDW) and mean platelet volume (MPV) are considered to be associated with tumors. We investigated the diagnostic value of RDW, MPV, and cancer antigen 125 (CA125), alone or in combination, in the diagnosis of endometrial cancer and endometrial hyperplasia. METHODS:This study incl...

journal_title：Journal of clinical laboratory analysis

authors： Zhang H,Liang K,Ke L,Tang S

更新日期：2020-08-01 00:00:00

abstract：:Preeclampsia continues to be a major cause of maternal and perinatal mortality and morbidity worldwide. The etiopathogenesis of preeclampsia is not fully understood. Neopterin and interleukin-2 (IL-2) production reflects cellular immunity. Our purpose was to determine the levels of neopterin and interleukin-2 receptor...

journal_title：Journal of clinical laboratory analysis

authors： Kaleli I,Kaleli B,Demir M,Yildirim B,Cevahir N,Demir S

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) are a special class of endogenous noncoding RNAs that have numerous biological functions in normal situation and diseases including cancers. However, the clinical significance of circRNAs in gastric cancer (GC) remains largely unknown. Here, we chose two representative circRNAs, hsa_...

journal_title：Journal of clinical laboratory analysis

authors： Lu R,Shao Y,Tao X,Ye G,Xiao B,Guo J

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:We aimed to assess the predictive value of long noncoding RNAs antisense noncoding RNA in the INK4 locus (lncRNAs ANRIL) for acute exacerbation of chronic obstructive pulmonary disease (COPD) and evaluate its correlation with inflammatory cytokines as well as the Global Initiative for Chronic Obstructive Lun...

journal_title：Journal of clinical laboratory analysis

authors： Ge J,Geng S,Jiang H

更新日期：2019-02-01 00:00:00

abstract：:A radioactive polymerase chain reaction (PCR) method has been developed for the relative quantification of the human alpha-2 chain of type I collagen [hu alpha-2(I)] in cells. cDNAs generated by reverse transcription from the total pool of cytoplasmic RNA serve as a template for polymerase chain reaction amplification...

journal_title：Journal of clinical laboratory analysis

authors： Yu YL,Golden JA,Migchielsen AA,Goetzl EJ,Turck CW

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) prevalence in rheumatoid arthritis (RA) patients is known to vary considerably across the world. This study aimed to determine the prevalence of MetS in RA patients from western Mexico and to analyze the interrelation of the MetS components with the clinical variables of RA. METHOD...

journal_title：Journal of clinical laboratory analysis

authors： García-Chagollán M,Hernández-Martínez SE,Rojas-Romero AE,Muñoz-Valle JF,Sigala-Arellano R,Cerpa-Cruz S,Morales-Núñez JJ,Lomelí-Nieto JA,Macedo Ojeda G,Hernández-Bello J

更新日期：2020-11-24 00:00:00

abstract：:The newly developed immunoblot assay, RIBA SIA (recombinant and synthetic polypeptide immunoblot assay), Chiron, Calif., was compared with the commercially available second generation recombinant immunoblot assay (RIBA-2) for the detection of antibody to hepatitis C virus (anti-HCV). The two immunoblot tests were also...

journal_title：Journal of clinical laboratory analysis

authors： Chaudhary RK,Andonov A,MacLean C

更新日期：1993-01-01 00:00:00

abstract：:The genetic basis of infertility has received increasing recognition in recent years, particularly with the advent of assisted reproductive technology. It is now becoming obvious that genetic etiology for infertility is an important cause of disrupted spermatogenesis. Y-chromosome microdeletions and abnormal karyotype...

journal_title：Journal of clinical laboratory analysis

authors： Abid S,Maitra A,Meherji P,Patel Z,Kadam S,Shah J,Shah R,Kulkarni V,Baburao V,Gokral J

更新日期：2008-01-01 00:00:00

abstract：:Medical treatment for Helicobacter pylori (Hp) infection is now recommended in several types of gastroduodenal disease, and its success is usually monitored by hystology. The end-points of our work were to identify the most suitable serum index of Hp eradication among pepsinogen A (PGA), pepsinogen C (PGC), PGA/PGC ra...

journal_title：Journal of clinical laboratory analysis

authors： Plebani M,Basso D,Scrigner M,Toma A,Di Mario F,Dal Bò N,Samloff IM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Iron overload is a major complication in patients with hemoglobin H (Hb H) disease and causes damage of tissues. METHODS:We investigated 26 Hb H patients and 75 controls to evaluate their oxidative stress and antioxidant statuses. RESULTS:There were significantly increased levels of superoxide anion in leu...

journal_title：Journal of clinical laboratory analysis

authors： Chiou SS,Tsao CJ,Tsai SM,Wu YR,Liao YM,Lin PC,Tsai LY

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Today, the genetic and genomic research entered in a new era of high-throughput genotyping technology. However, mutagenic polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is still a choice of genotyping method in molecular epidemiological research. It has been extensively used fo...

journal_title：Journal of clinical laboratory analysis

authors： Sharma N,Awasthi S,Phadke SR

更新日期：2016-03-01 00:00:00

abstract：:The present study was designed to evaluate whether the use of acid citrate dextrose (ACD) Formula A may enhance the survival of platelets during storage, thus allowing the continuance of platelet studies over the period of 2-3 hours usually recommended. For this purpose the effects of time on in vitro platelet respons...

journal_title：Journal of clinical laboratory analysis

authors： Pignatelli P,Pulcinelli FM,Ciatti F,Pesciotti M,Ferroni P,Gazzaniga PP

更新日期：1996-01-01 00:00:00

abstract：:C-peptide is secreted in equimolar concentrations with insulin, and is often measured to assess pancreatic beta-cell function. C-peptide analysis is most often performed by radioimmunoassay (RIA) which has several disadvantages. We evaluated an automated, chemiluminescent immunoassay for C-peptide in terms of precisio...

journal_title：Journal of clinical laboratory analysis

authors： Hardy RW,Cohn M,Konrad RJ

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that adiponectin (APN) could ameliorate ischemia/reperfusion injury and endothelial dysfunction in patients with acute myocardial infarction. However, the relationship between serum APN level and coronary flow after primary percutaneous coronary intervention (PPCI) in patients with...

journal_title：Journal of clinical laboratory analysis

authors： Liang S,Li H,Shen X,Liu R

更新日期：2019-06-01 00:00:00

abstract：:The matrix metalloproteinase matrilysin (MMP-7) is a member of the matrix metalloproteinase gene family, which is believed to play an important role in tumor invasion and metastasis. We have previously found that matrilysin mRNA is specifically expressed in colorectal cancers and adenomas and that its message is local...

journal_title：Journal of clinical laboratory analysis

authors： Yamamoto H,Itoh F,Senota A,Adachi Y,Yoshimoto M,Endoh T,Hinoda Y,Yachi A,Imai K

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Alport syndrome (ATS) is a hereditary nephritis with hereditary and clinical heterogeneity; the early clinical symptoms are atypical, which can easily lead to misdiagnosis. The proband, a 6-year-old girl, was found to have microscopic hematuria, proteinuria, and visual impairment at about 5 years old; the re...

journal_title：Journal of clinical laboratory analysis

authors： Zhu Q,Zhou C,Wang J

更新日期：2020-09-06 00:00:00

abstract：BACKGROUND:Diverse and circumstantial evidence suggests that schizophrenia is a neurodevelopmental disorder. Genes contributing to neurodevelopment may be potential candidates for schizophrenia. The human SOX11 gene is a member of the developmentally essential SOX (Sry-related HMG box) transcription factor gene family ...

journal_title：Journal of clinical laboratory analysis

authors： Sun CP,Sun D,Luan ZL,Dai X,Bie X,Ming WH,Sun XW,Huo XX,Lu TL,Zhang D

更新日期：2020-08-01 00:00:00

abstract：:Type IV collagen is a major component released from the glomerular and tubular basement membranes. To investigate the alteration of renal type IV collagen turnover in early stage diabetic nephropathy, urinary type IV collagen was measured by a highly sensitive one-step sandwich enzyme immunoassay (EIA). Urinary sample...

journal_title：Journal of clinical laboratory analysis

authors： Iijima T,Suzuki S,Sekizuka K,Hishiki T,Yagame M,Jinde K,Saotome N,Suzuki D,Sakai H,Tomino Y

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND & AIM:Hepatitis B virus-e-antigen (HBeAg) is an affordable viral marker to assess viral replication kinetics and response to antiviral therapy. In the absence of confirmatory assays, discrepant or false-positive HBeAg results are resolved by screening for other HBV markers. We standardized an in-house HBeAg ...

journal_title：Journal of clinical laboratory analysis

authors： Fletcher GJ,Anantharam R,Radhakrishnan K,Karunakaran A,Abraham P

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The prevalence of diabetes is increasing in China. Glucose control is very important in diabetic patients. The aim of this study was to compare the accuracy of five glucose meters used in Chinese hospitals with a reference method, in the absence and presence of various factors that may interfere with the met...

journal_title：Journal of clinical laboratory analysis

authors： Lv H,Zhang GJ,Kang XX,Yuan H,Lv YW,Wang WW,Randall R

更新日期：2013-09-01 00:00:00