Abstract:
:Here we completely sequenced four mcr-1-haboring plasmids, isolated from two extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli and two carbapenemase-producing Klebsiella pneumoniae clinical isolates. The mcr-1-harboring plasmids from an E. coli sequence type 2448 (ST2448) isolate and two K. pneumoniae ST25 isolates were identical (all pMCR1-IncX4), belonging to the IncX4 incompatibility group, while the plasmid from an E. coli ST2085 isolate (pMCR1-IncI2) belongs to the IncI2 group. A nearly identical 2.6-kb mcr-1-pap2 element was found to be shared by all mcr-1-carrying plasmids.
journal_name
Antimicrob Agents Chemotherjournal_title
Antimicrobial agents and chemotherapyauthors
Li A,Yang Y,Miao M,Chavda KD,Mediavilla JR,Xie X,Feng P,Tang YW,Kreiswirth BN,Chen L,Du Hdoi
10.1128/AAC.00550-16subject
Has Abstractpub_date
2016-06-20 00:00:00pages
4351-4issue
7eissn
0066-4804issn
1098-6596pii
AAC.00550-16journal_volume
60pub_type
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