Abstract：
:Depression might be associated with shorter disease specific survival. Selective serotonin reuptake inhibitors (SSRIs) were previously reported to increase the risk of certain malignancies. We aimed to evaluate the impact of SSRIs on cancer mortality. Five retrospective cohort studies were conducted in a UK population-representative database that included all individuals with an incident diagnosis of melanoma, breast, prostate lung and colorectal cancer. The primary exposure of interest was continuous use of SSRIs with past use as the comparison reference. Cox regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CI). The study included 5,591 newly diagnosed cancer patients. Continuous SSRI use was associated with lower survival compared to past users for melanoma, breast, prostate, lung and colorectal cancers with HRs for the risk of death of 2.02 (95% CI 1.24-3.28), 1.91 (95% CI 1.53-2.38), 1.79 (95% CI 1.38-2.33), 1.44 (95% CI 1.19-1.75) and 1.51 (95% CI 1.21-1.72) respectively. The incidence of death during the first 2 years following cancer diagnosis associated with continuous SSRI use were elevated for breast (1.72, 95% CI 1.30-2.27), prostate (1.64, 95% CI 1.20-2.24) and lung cancers (1.45, 95% CI 1.26-1.66). In conclusion, continuous use of SSRIs might be associated with lower survival in cancer patients.
journal_name
Eur J Cancer Care (Engl)journal_title
European journal of cancer careauthors
Boursi B,Lurie I,Haynes K,Mamtani R,Yang YXdoi
10.1111/ecc.12666subject
Has Abstractpub_date
2018-01-01 00:00:00issue
1eissn
0961-5423issn
1365-2354journal_volume
27pub_type
杂志文章abstract：:The aim of this study has been to explore the concept of rehabilitation as a team activity in the oncology setting. The researcher has interviewed 15 members of the rehabilitation team in a specialist oncology rehabilitation centre in the United Kingdom and observed the day-to-day activity in the centre. The grounded ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.1993.tb00182.x
更新日期：1993-01-01 00:00:00
abstract：:During 2008-2009, only 4% of women targeted for cervical screening were screened in Tshwane, South Africa. The purpose of the study was to determine whether cervical screening uptake could be improved when breast and cervical screening are combined. An intervention research design was used. The intervention was assess...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2011.01292.x
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abstract：:This small-scale study aimed to provide an insight into the time between first noticing a symptom, attending a healthcare provider and obtaining a cancer diagnosis. Previous research showed that the pre-diagnostic moments on the illness trajectory were important to people with cancer and could influence levels of sati...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1046/j.1365-2354.2003.00418.x
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abstract：:Delays in the diagnosis of cancer are common, and they are attributed to both patient and healthcare system factors. Minimizing such delays and improving early detection rates is a key goal of the new cancer reform strategy in England, in light of recent data showing that survival rates in the UK are low. The aim of t...
journal_title：European journal of cancer care
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1365-2354.2008.01020.x
更新日期：2010-01-01 00:00:00
abstract：:Randomized controlled trials are accepted to be the research design of choice to evaluate the effectiveness of health care interventions and are commonly used to evaluate cancer treatments. There are concerns, however, that levels of recruitment to trials are often much lower than anticipated, particularly in cancer t...
journal_title：European journal of cancer care
pub_type： 杂志文章,meta分析
doi：10.1046/j.1365-2354.2002.00341.x
更新日期：2002-09-01 00:00:00
abstract：:Despite advances in surgical treatments and the availability of more conservative treatment options, women treated for vulval cancer still experience significant complications such as urinary incontinence, lymphoedema, pruritus, sexual and intimacy issues. These issues can profoundly impact a woman's quality of life. ...
journal_title：European journal of cancer care
pub_type： 杂志文章,多中心研究
doi：10.1111/ecc.12465
更新日期：2017-01-01 00:00:00
abstract：:Management of cytotoxic drug extravasation remains contentious, with differing views on the most effective management strategy. With the increasing drive to provide effective, evidence-based healthcare, while ensuring the patient experience of the treatment provided plays a significant part in the development of clini...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1111/ecc.12363
更新日期：2015-11-01 00:00:00
abstract：:We have investigated a relational model of expectations and preferences among ovarian cancer patients centred on physician-patient communication, treatment approach, and the need for information. Consecutive patients anonymously filled in the EXPRESSION III questionnaire between 2009 and 2012. Following descriptive st...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12566
更新日期：2017-11-01 00:00:00
abstract：:Previous reports on the patient perspective of daily life during a 1-year high-grade glioma (HGG) trajectory from the time of diagnosis are sparse. The aim of this longitudinal mixed methods study is to identify the specific needs and preferences for rehabilitation and supportive care and how it links with physical ac...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12806
更新日期：2018-03-01 00:00:00
abstract：:Effective patient-professional communication can be of crucial importance to long-term psycho-social outcomes in patients with cancer. This study identifies patient satisfaction with regard to various aspects of communication and perceived quality of care. A well-validated questionnaire was administered to 435 cancer ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2005.00530.x
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:Breast cancer treatments not only affect body image but also other aspects of women's lives. Women try to accept their appearance through coping strategies. This study aimed to determine the relationship between body image and coping strategies in women with breast cancer following surgery in southeast Iran. ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.13191
更新日期：2020-01-01 00:00:00
abstract：:To investigate health professionals' perspectives about factors that impede or facilitate cancer care for Indigenous people. Semi-structured interviews with 22 health professionals involved in Indigenous cancer care. Data were interpreted using an inductive thematic analysis approach. Participants presented their pers...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12467
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:Fear of cancer recurrence (FCR) is the most commonly reported problem and unmet need among breast cancer survivors. The aim of this qualitative study was to explore the experience of recurrence fears among Taiwanese breast cancer survivors. METHODS:Three focus groups were included in this study. A purposive ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.13113
更新日期：2019-09-01 00:00:00
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journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2008.01034.x
更新日期：2009-05-01 00:00:00
abstract：:Increasing numbers of cancer survivors and the tradition of long-term follow-up in the outpatient clinic has resulted in overcrowded oncology clinics and long waiting times. Little is known about patients' perceptions of their clinic attendance. This survey of 252 oncology patients investigated patients' satisfaction ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.1997.tb00269.x
更新日期：1997-03-01 00:00:00
abstract：:Osteolytic bone disease is a frequent complication of multiple myeloma, resulting in skeletal complications that are a significant cause of morbidity and mortality. It is the result of an increased activity of osteoclasts, which is not followed by reactive bone formation by osteoblasts. Recent studies have revealed no...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1111/ecc.12761
更新日期：2017-11-01 00:00:00
abstract：:The aim of this study was to conduct a systematic review of the literature on the needs of adolescents and young adults (AYAs) who have survived cancer. PRISMA recommendations for systematic reviews were followed, and the quality of the studies reviewed was also assessed with a specific checklist. The following databa...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12558
更新日期：2018-11-01 00:00:00
abstract：:The aim of this study was to compare the efficacy of cryotherapy and chlorhexidine to oral nutrition transition time in chemotherapy-induced oral mucositis. This randomised controlled trial with random assignments to the experimental and control groups was conducted with cancer patients. Study data were collected from...
journal_title：European journal of cancer care
pub_type： 杂志文章,随机对照试验
doi：10.1111/ecc.12495
更新日期：2017-09-01 00:00:00
abstract：:The emotional turmoil patients endure following a diagnosis of cancer can impair their ability to retain complex treatment-related information. Manoeuvres which increase the intensity of information have been shown to increase the amount retained. Providing details of treatment in a video format is one method of inten...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1046/j.1365-2354.1999.00123.x
更新日期：1999-06-01 00:00:00
abstract：:Patients with various forms of cancer receiving blood and marrow transplant (BMT) treatment at an outpatient clinic develop chemotherapy-related symptoms and an increased desire to use complementary and alternative medicine in order to address these symptoms. Art-making offers an inexpensive way to pass time and relie...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/ecc.12482
更新日期：2017-09-01 00:00:00
abstract：:This study aimed to identify high support needs and their socio-demographic predictors to improve supportive care for newly diagnosed breast cancer patients. A cross-sectional study measured patients' needs and unsatisfied support needs by the supportive care needs survey (SCNS-34), administered after surgery, chemoth...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2010.01190.x
更新日期：2011-07-01 00:00:00
abstract：:The House of Commons Select Committee on Science and Technology 2000 state that currently less than 5% of adult patients with solid tumours are entered into clinical trials. They recommend that increasing the number of adult cancer patients entering clinical trials must become a high priority. Health-care providers ne...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：
更新日期：2002-03-01 00:00:00
abstract：:The majority of people who are bereaved will work through their grief with support from family and friends. Over 30%, however, may require professional support, and studies have shown that most people contact their General Practitioner and primary health-care team for counselling/support. Effective support and counsel...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.1995.tb00048.x
更新日期：1995-03-01 00:00:00
abstract：:Drug interactions are commonly seen in the treatment of cancer patients. Psychotropics are often indicated for these patients since they may also suffer from pre-existing psychological disorders or experience insomnia and anxiety associated with cancer therapy. Thus, the risk of anticancer drug (ACD)-psychotropic drug...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1111/j.1365-2354.2009.01113.x
更新日期：2011-01-01 00:00:00
abstract：:Surgical cytoreduction and platinum/taxane combination chemotherapy are the mainstay for the treatment of epithelial ovarian cancer patients. In order to minimise the tumour mass before chemotherapy, cytoreductive surgery is usually performed first. Currently, a splenectomy is included as part of surgical cytoreductio...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
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更新日期：2011-05-01 00:00:00
abstract：:The aim of this study was to describe the information and support needs of women who have primary relatives with breast cancer. The Information and Support Needs Questionnaire (ISNQ) was developed and revised from previous qualitative and pilot studies. The ISNQ addressed concepts of the importance of, and the degree ...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1046/j.1365-2354.2003.00330.x
更新日期：2003-03-01 00:00:00
abstract：:The objectives of this study are to evaluate patient outcomes in clinical practice using gemcitabine and carboplatin (GCarbo) as first-line treatment in metastatic transitional cell carcinoma (TCC) of the urothelium, and to review the published evidence on the use of GCarbo in this setting. From July 2003, all cases o...
journal_title：European journal of cancer care
pub_type： 杂志文章,评审
doi：10.1111/j.1365-2354.2008.01050.x
更新日期：2010-05-01 00:00:00
abstract：:To assess the responsiveness and interpretability of the Quality of Working Life Questionnaire for Cancer Survivors (QWLQ-CS). A cohort study was conducted in which 130 (self-)employed cancer survivors completed the QWLQ-CS at baseline and 107 at follow-up and six single-item external anchors to measure change. Cancer...
journal_title：European journal of cancer care
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abstract：:We assessed the quality of life (QoL) associated with patient's characteristics and different cancer treatments among Chinese breast cancer survivors in Taiwan. A cross-sectional survey was conducted in 2017 where 193 patients with hormone receptor-positive/human epidermal growth factor receptor-2-negative metastatic ...
journal_title：European journal of cancer care
pub_type： 杂志文章
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更新日期：2019-07-01 00:00:00
abstract：:The objective of this study was to clarify the term 'palliative' in clinical oncology. A qualitative study design with in-depth interviews was applied. The study sample included 30 cancer patients and 16 physicians. In clinical oncology, the use of the term 'palliative' to describe both anticancer treatments and palli...
journal_title：European journal of cancer care
pub_type： 杂志文章
doi：10.1111/j.1365-2354.2004.00481.x
更新日期：2004-07-01 00:00:00
