Abstract:
:The House of Commons Select Committee on Science and Technology 2000 state that currently less than 5% of adult patients with solid tumours are entered into clinical trials. They recommend that increasing the number of adult cancer patients entering clinical trials must become a high priority. Health-care providers need to prepare themselves for this proposed increase in trial participants by assessing the current status of care and implementing changes within the current infrastructure to provide optimal holistic care. Cancer can change a patient's life either for better or for worse. At one extreme, having cancer leads to enhanced appreciation of life and closer bonds with others. However, at the other extreme, cancer combined with its treatment is viewed as an event that evokes distress and emotional anguish taxing the individual's ability to cope. In the last 25 years, owing to the advent of clinical trials, progress has been made in cancer treatment. Clinical trials may be hailed as the saviour to many therapeutic dilemmas. Treatments are now available which can offer patients hope of cure. Nevertheless, many participants may fear, for the purpose of research, that they may be assigned to less than optimal therapy or that their care will be carried out in a sterile scientific atmosphere devoid of humane and personal consideration. These and other reasons may cause unacceptable personal distress that overrides the potential therapeutic gain. Cancer diagnosis coupled with the ramifications of clinical trial involvement can have significant psychological implications. They may trigger the onset of a mood disorder or exacerbate a present symptom. This article will identify mood disorders in the cancer population, focus on the participants' needs in the clinical trial arena and investigate the influence trial participation has on psychological status.
journal_name
Eur J Cancer Care (Engl)journal_title
European journal of cancer careauthors
Kelly C,Ghazi F,Caldwell Ksubject
Has Abstractpub_date
2002-03-01 00:00:00pages
6-15issue
1eissn
0961-5423issn
1365-2354pii
283journal_volume
11pub_type
杂志文章,评审abstract::Increasing numbers of cancer survivors and the tradition of long-term follow-up in the outpatient clinic has resulted in overcrowded oncology clinics and long waiting times. Little is known about patients' perceptions of their clinic attendance. This survey of 252 oncology patients investigated patients' satisfaction ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.1997.tb00269.x
更新日期:1997-03-01 00:00:00
abstract::The aim of this study is to explore, from a medical sociological perspective, the use of complementary therapies by palliative care nurses. This paper shows how the conceptual vocabulary developed by Giddens [Giddens A. (1990) The Consequences of Modernity. Polity Press, Cambridge; Giddens A. (1991) Modernity and Self...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1046/j.1365-2354.2003.00381.x
更新日期:2003-06-01 00:00:00
abstract::Although it is quite rare, second primary neoplasms in cancer patients may present with the signs and symptoms of malignant spinal cord compression. Primary spinal cord tumours in the cancer patients may be deceptive and considered as the recurrent first cancer. Therefore, it should be precisely differentiated and app...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2354.2006.00708.x
更新日期:2006-12-01 00:00:00
abstract::This study explored men's experiences of transrectal prostate biopsy. Fifty men who had had a prostate biopsy talked about the experience as part of an in-depth interview; 36 were interviewed in 2000 about all aspects of prostate cancer, and 14 in 2005 about their experience of prostate-specific antigen testing, subse...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2006.00766.x
更新日期:2007-05-01 00:00:00
abstract::Cancer is the leading cause of death and one of the most significant healthcare expenses in Korea. The purpose of this study was to estimate the economic burden of cancer on Korean society. We studied the medical, non-medical, morbidity and mortality costs related to cancer treatment, lost productivity and premature d...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2007.00818.x
更新日期:2008-03-01 00:00:00
abstract::The study aimed to evaluate cancer-targeting potential of a newly synthesised radiopharmaceutical, 99m Tc-resveratrol in vivo, using colon cancer model. Colon cancer was induced in 20 male Sprague-Dawley rats by subcutaneous administration of 1,2-dimethylhydrazine (DMH), dissolved in 1 mM EDTA-normal saline, at a dose...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12504
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To examine follow-up procedures after men are discharged into primary care following prostate cancer and highlight any areas for service improvement. METHODS:Patient record data from two Greater Manchester boroughs were retrieved retrospectively to investigate discharge instructions and monitoring adherence....
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13389
更新日期:2020-12-18 00:00:00
abstract::To assess the responsiveness and interpretability of the Quality of Working Life Questionnaire for Cancer Survivors (QWLQ-CS). A cohort study was conducted in which 130 (self-)employed cancer survivors completed the QWLQ-CS at baseline and 107 at follow-up and six single-item external anchors to measure change. Cancer...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12910
更新日期:2018-11-01 00:00:00
abstract::The aims were to investigate whether: (A) doctors' ability to identify patients' worry about prognosis/wish for information about disease and treatment is related to doctors' self-efficacy with regard to communicating about difficult matters and patients' satisfaction with a consultation/hope to live a good life in sp...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2006.00670.x
更新日期:2006-09-01 00:00:00
abstract::The objectives of this study are to evaluate patient outcomes in clinical practice using gemcitabine and carboplatin (GCarbo) as first-line treatment in metastatic transitional cell carcinoma (TCC) of the urothelium, and to review the published evidence on the use of GCarbo in this setting. From July 2003, all cases o...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2354.2008.01050.x
更新日期:2010-05-01 00:00:00
abstract::Sarcomas often occur in patients' extremities and treatment typically involves bone resection/limb salvage surgery. Such treatments leave survivors with physical disfigurements, functional disabilities, and/or emotional traumas. Our post-surgery psychological intervention investigated how these experiences impinge on ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12667
更新日期:2017-11-01 00:00:00
abstract::This study aimed at developing and measuring quality indicators for oesophageal cancer (OC) and gastric cancer (GC) and to support quality improvement for practitioners. Quality indicators were identified from a systematic literature search including clinical guidelines. The selection process involved experts evaluati...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/ecc.12279
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:The goal of our study was to evaluate the reliability, validity, responsiveness and acceptability of the Mandarin (simplified) Chinese version of the EORTC QLQ-OH45. METHODS:From October 2017 to February 2018, 393 cancer patients were enrolled from three different hospitals in China. A forward and backward tra...
journal_title:European journal of cancer care
pub_type: 杂志文章,多中心研究
doi:10.1111/ecc.12987
更新日期:2019-03-01 00:00:00
abstract::Across Australia, prostate cancer support groups (PCSG) have emerged to fill a gap in psychosocial care for men and their families. However, an understanding of the triggers and influencers of the PCSG movement is absent. We interviewed 21 SG leaders (19 PC survivors, two partners), of whom six also attended a focus g...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12644
更新日期:2018-03-01 00:00:00
abstract::As part of a major study of the impact of childhood cancer on Chinese families, 17 families agreed to be interviewed after the death of their child from cancer. They convey what happens to the child's body after death and what remembrances the family has kept of their child's belongings. They share how they have adjus...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.1993.tb00192.x
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Three different models are commonly used to provide palliative care services to cancer patients in Turkey: comprehensive palliative care center (CPCC), hospital inpatient services (HIS) and home healthcare (HHC). OBJECTIVES:The purpose of this study was to evaluate the cost-effectiveness of three alternativ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13110
更新日期:2019-09-01 00:00:00
abstract::This is the first of a two-part paper on quality of life in cancer patients. This part examines some of the fundamental issues in health-related quality of life measurement with particular attention being given to cancer medicine, thus helping to focus the direction and methodological rigour required in future investi...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2354.1996.tb00228.x
更新日期:1996-09-01 00:00:00
abstract::In South Africa, cervical cancer is the most common female cancer followed by breast cancer. Despite the high incidence of these cancers, population-based screening is limited to cervical screening available at primary health clinics. Cervical screening uptake is, however, low. In 2009 a new cancer prevention initiati...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12005
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:Documentations of the experiences of patients with advanced prostate cancer and their partners are sparse. Views of care and treatment received for metastatic castrate-resistant prostate cancer (mCRPC) are presented here. METHODS:Structured interviews conducted within 14 days of a systemic therapy for mCRPC ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13140
更新日期:2019-11-01 00:00:00
abstract::The incidence and number of deaths from soft tissue sarcoma (STS) have been reported to increase in many countries. However, those in Japan have not been analysed over a long span of time. The objective of this study was to analyse the changing trends in the number of deaths from STS in Japan. We analysed the annual t...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2005.00640.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:Breast cancer treatments not only affect body image but also other aspects of women's lives. Women try to accept their appearance through coping strategies. This study aimed to determine the relationship between body image and coping strategies in women with breast cancer following surgery in southeast Iran. ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13191
更新日期:2020-01-01 00:00:00
abstract::The efficacy of traditional follow-up care is being challenged, as cancer survivors' supportive and psychological needs are often neither identified, nor addressed. This study's aim was to develop a holistic surgical follow-up clinic for oral and oropharyngeal cancer patients were participants completed a disease-spec...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12809
更新日期:2018-03-01 00:00:00
abstract::The fear of cancer recurrence is cited as a motivator of women's preferences between routine monitoring and contralateral prophylactic mastectomy (CPM) as methods of managing ongoing breast cancer risk. We conducted a discrete choice experiment among a general community sample of women who completed 12 hypothetical ch...
journal_title:European journal of cancer care
pub_type: 杂志文章,随机对照试验
doi:10.1111/ecc.13058
更新日期:2019-07-01 00:00:00
abstract::This paper reports on a study into male participation in cancer support groups, which elicited data on the impact of cancer on masculinities. This small qualitative pilot study, which took place in Belfast in Northern Ireland, involved semi-structured interviews with eight men with a history of cancer who were no long...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/j.1365-2354.2009.01085.x
更新日期:2010-07-01 00:00:00
abstract::The reasons why teenagers and young adults (TYA) with cancer do, or do not, participate in clinical trials is not wholly understood. We explored the perceptions and experiences of young people with bone cancer, and health professionals involved in their care, with regard to participation in two clinical trials. We con...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12476
更新日期:2018-11-01 00:00:00
abstract::Patients with various forms of cancer receiving blood and marrow transplant (BMT) treatment at an outpatient clinic develop chemotherapy-related symptoms and an increased desire to use complementary and alternative medicine in order to address these symptoms. Art-making offers an inexpensive way to pass time and relie...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12482
更新日期:2017-09-01 00:00:00
abstract:INTRODUCTION:Ecological momentary assessment (EMA) is an emerging method to assess an individual's current thoughts, affect, behaviour, physical states and contextual factors as they occur in real-time and in their natural environment. Whereas EMA is frequently used in mental health, little is known about the added val...
journal_title:European journal of cancer care
pub_type: 杂志文章,评审
doi:10.1111/ecc.13095
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:Fear of cancer recurrence (FCR) is the most commonly reported problem and unmet need among breast cancer survivors. The aim of this qualitative study was to explore the experience of recurrence fears among Taiwanese breast cancer survivors. METHODS:Three focus groups were included in this study. A purposive ...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.13113
更新日期:2019-09-01 00:00:00
abstract::The aim of this study was to describe family members' life situation and experiences of care in two different care settings, the patient's home or in hospital during the acute post-transplantation phase after allogeneic haematopoietic stem cell transplantation (HSCT). Data were collected through semi-structured interv...
journal_title:European journal of cancer care
pub_type: 杂志文章
doi:10.1111/ecc.12610
更新日期:2018-01-01 00:00:00
abstract::Based on promising preclinical data, a progressive series of evaluations of the use of high-dose mitoxantrone-based chemotherapy was initiated in acute leukaemia patients. A preliminary phase I study demonstrated that up to 80 mg/m2 of mitoxantrone in combination with cytarabine 3 g/m2 daily for 5 days could be given ...
journal_title:European journal of cancer care
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1111/j.1365-2354.1997.tb00322.x
更新日期:1997-12-01 00:00:00