Abstract:
:The management of clinically localized renal masses suspicious for renal cell carcinoma varies, partially because of gaps in the evidence base. We conducted a systematic review to summarize research gaps for the evaluation of composite models for predicting malignancy; use of percutaneous renal sampling for diagnosis; and comparative effectiveness of surgery, thermal ablation, and active surveillance. A total of 147 studies, published in 150 articles, were identified. To promote improved patient care and health outcomes, we recommend incorporation of emerging biomarkers into validated composite models, standardization of biopsy protocols, standard reporting of clinical stage, and performance of prospective studies with objective selection criteria.
journal_name
Urologyjournal_title
Urologyauthors
Patel HD,Iyoha E,Pierorazio PM,Sozio SM,Johnson MH,Sharma R,Bass EB,Allaf MEdoi
10.1016/j.urology.2016.08.013subject
Has Abstractpub_date
2016-12-01 00:00:00pages
14-20eissn
0090-4295issn
1527-9995pii
S0090-4295(16)30520-9journal_volume
98pub_type
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