Abstract：
BACKGROUND:Intracranial extraskeletal mesenchymal chondrosarcomas (MCSs) are rare tumors accounting for <0.16% of intracranial tumors. They are usually described as occurring in the age group of 20-30 years and are commonly found in the frontoparietal region arising from the falx and surrounding dura. We describe 3 cases at varying ages, locations, and outcomes. CASE DESCRIPTION:A 42-year-old woman with anterior one third falx-based lesion; a 7-year-old boy with mid one third falcine lesion with hyperostosis of bone, presenting in comatose stage; and a 52-year-old woman with left posterior lateral frontal dural-based lesion are presented. Histopathology of all cases was confirmed with immunohistochemistry. All patients underwent complete excision but had varying outcomes. CONCLUSIONS:Intracranial MCSs are rare malignant tumors with poor prognosis. Because of their rarity, it may not be considered as a differential diagnosis and it is often misdiagnosed radiologically, but the importance lies in the need of radical excision. The potential effect of postoperative radiotherapy and chemotherapy is controversial. This article sheds some light on variable prognosis of this tumor.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Sadashiva N,Sharma A,Shukla D,Rajalakshmi P,Mahadevan A,Devi BIdoi
10.1016/j.wneu.2016.08.049subject
Has Abstractpub_date
2016-11-01 00:00:00pages
618.e1-618.e6eissn
1878-8750issn
1878-8769pii
S1878-8750(16)30716-1journal_volume
95pub_type
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