Impaired cardiorespiratory fitness after aneurysmal subarachnoid hemorrhage.

Abstract:

OBJECTIVE:To assess cardiorespiratory fitness in patients following an aneurysmal subarachnoid haemorrhage and to explore this in fatigued and non-fatigued patients. DESIGN:Cross-sectional case-control study. SUBJECTS/PATIENTS:A total of 28 patients, 6 months post aneurysmal subarachnoid haemorrhage, and 28 sex- and age-matched controls. METHODS:Cardiorespiratory responses to a progressive cardiopulmonary exercise test on a cycle ergometer were obtained using indirect calorimetry. Fatigue was assessed using the Fatigue Severity Scale. RESULTS:Mean peak oxygen uptake (V̇O2peak) was significantly lower in patients (22.0 (standard deviation (SD) 6.2) ml/kg/min) than in controls (69% of controls, p < 0.001). All other cardiorespiratory fitness parameters were also lower, with peak levels ranging from 62% to 77% of matched controls. Mean V̇O2peak was 19.4 (SD 4.1) ml/kg/min in fatigued patients (63% of matched controls, p < 0.001) and 23.9 (SD 6.9) ml/kg/min in non-fatigued patients (74% of matched controls, p = 0.002). CONCLUSION:Cardiorespiratory fitness is impaired after aneurysmal subarachnoid haemorrhage, both in fatigued and non-fatigued patients. This finding may have implications for treatment.

journal_name

J Rehabil Med

authors

Harmsen WJ,Ribbers GM,Zegers B,Sneekes EM,Heijenbrok-Kal MH,Khajeh L,van Kooten F,Neggers SJ,van den Berg-Emons RJ

doi

10.2340/16501977-2127

subject

Has Abstract

pub_date

2016-10-12 00:00:00

pages

769-775

issue

9

eissn

1650-1977

issn

1651-2081

journal_volume

48

pub_type

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