Abstract:
:In this report, we demonstrate that myogenic cultures inhibited from differentiating by treatment with fibroblast growth factor or transforming growth factor beta show reduced levels of MyoD1 mRNA. Although this repression may contribute to the inhibition of myogenesis by growth factors, additional regulatory pathways must be affected, since inhibition still occurs in cultures engineered to constitutively express MyoD1 mRNA.
journal_name
Mol Cell Bioljournal_title
Molecular and cellular biologyauthors
Vaidya TB,Rhodes SJ,Taparowsky EJ,Konieczny SFdoi
10.1128/mcb.9.8.3576subject
Has Abstractpub_date
1989-08-01 00:00:00pages
3576-9issue
8eissn
0270-7306issn
1098-5549journal_volume
9pub_type
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pub_type: 杂志文章
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doi:10.1128/mcb.20.1.379-388.2000
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abstract::RNA editing of specific residues by adenosine deamination is a nuclear process catalyzed by adenosine deaminases acting on RNA (ADAR). Different promoters in the ADAR1 gene give rise to two forms of the protein: a constitutive promoter expresses a transcript encoding (c)ADAR1, and an interferon-induced promoter expres...
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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