Delayed Obstruction With Asymptomatic Loss of Renal Function After Dextranomer/Hyaluronic Acid Copolymer (Deflux) Injection for Vesicoureteral Reflux: A Close Look at a Disturbing Outcome.

Abstract:

:Dextranomer/hyaluronic acid copolymer (Deflux) first received Food and Drug Administration approval in 2001 for endoscopic injection in children with grade II-IV vesicoureteral reflux VUR. As experience has grown, Deflux has been used more liberally with encouraging results. We report 3 cases where Deflux was used in off-label fashion, resulting in delayed ureteral obstruction and loss of renal function (range 18-52 months postoperatively). We now place increased emphasis on the need for long-term follow-up after Deflux in both routine and complex cases, particularly in situations of off-label use.

journal_name

Urology

journal_title

Urology

authors

Papagiannopoulos D,Rosoklija I,Cheng E,Yerkes E

doi

10.1016/j.urology.2016.09.013

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

63-66

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(16)30616-1

journal_volume

101

pub_type

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