Fear of recurrence, symptom burden, and health-related quality of life in men with prostate cancer.

Abstract:

OBJECTIVES:To examine the contributions of fear of recurrence and the more commonly examined treatment-related symptoms to the health-related quality of life (HRQOL) of men treated for localized prostate cancer. METHODS:A total of 730 men with localized disease were identified from the Cancer of the Prostate Strategic Urologic Research Endeavor, a national, prospective study of men with prostate cancer. Pre- to post-treatment changes in fear of recurrence, treatment-specific symptoms and burden, comorbidities at diagnosis, number of new symptoms, and post-treatment HRQOL data were analyzed. RESULTS:Linear regression, adjusted for clinical and demographic characteristics, showed that improved fear of recurrence (P <0.01), higher number of post-treatment symptoms (P <0.01), and improved bowel function (P <0.01) significantly predicted better mental health scores. For physical health, improved urinary bother (P <0.01) and lower number of post-treatment symptoms (P <0.01) were associated with better physical health. CONCLUSION:Understanding men's fears about cancer recurrence and how these fears influence physical and mental health are important components of providing care to this growing population.

journal_name

Urology

journal_title

Urology

authors

Bellizzi KM,Latini DM,Cowan JE,DuChane J,Carroll PR

doi

10.1016/j.urology.2007.12.084

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

1269-73

issue

6

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(07)02679-9

journal_volume

72

pub_type

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