Abstract:
:We investigated the effect of two diets containing equal amounts of the carcinogen FANFT on the incidence and induction time of murine bladder carcinoma in mice. At each time interval, the tumor incidence in the mice ingesting a purified, high-calorie diet, was equal or greater than the tumor incidence in the animals fed standard mouse chow. The mean animal weight of the mice ingesting the purified diet was consistently higher than that of the mice fed the standard diet. The bladder weights (an index of tumor volume) showed no significant difference between the mice receiving the two diets. Since mice eat to fulfill their caloric requirements, the animals ate less of the purified diet and the cost per year was lower.
journal_name
Urologyjournal_title
Urologyauthors
Soloway MS,Nissenkorn I,McCallum LWdoi
10.1016/0090-4295(81)90297-1subject
Has Abstractpub_date
1981-11-01 00:00:00pages
482-4issue
5eissn
0090-4295issn
1527-9995pii
0090-4295(81)90297-1journal_volume
18pub_type
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