Comparison between a purified and standard diet on FANFT-induced murine bladder cancer.

Abstract:

:We investigated the effect of two diets containing equal amounts of the carcinogen FANFT on the incidence and induction time of murine bladder carcinoma in mice. At each time interval, the tumor incidence in the mice ingesting a purified, high-calorie diet, was equal or greater than the tumor incidence in the animals fed standard mouse chow. The mean animal weight of the mice ingesting the purified diet was consistently higher than that of the mice fed the standard diet. The bladder weights (an index of tumor volume) showed no significant difference between the mice receiving the two diets. Since mice eat to fulfill their caloric requirements, the animals ate less of the purified diet and the cost per year was lower.

journal_name

Urology

journal_title

Urology

authors

Soloway MS,Nissenkorn I,McCallum LW

doi

10.1016/0090-4295(81)90297-1

subject

Has Abstract

pub_date

1981-11-01 00:00:00

pages

482-4

issue

5

eissn

0090-4295

issn

1527-9995

pii

0090-4295(81)90297-1

journal_volume

18

pub_type

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