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New p-terphenyls from the endophytic fungus Aspergillus sp. YXf3.

Abstract：

:Five new p-terphenyls named prenylterphenyllin D (1), prenylterphenyllin E (2), 2'-O-methylprenylterphenyllin (3), 4-O-methylprenylterphenyllin (4) and 3'-O-methylterphenyllin (5) together with seven known compounds (6-12), were isolated from cultures of Aspergillus sp. YXf3. The structures of the new compounds were elucidated by extensive MS and NMR analyses. The NMR and MS data of 5 is reported for the first time, as its structure was listed in SciFinder Scholar with no associated reference. Compounds 6 and 7 were distinguished from each other on the basis of 2D NMR experiments. Compounds 1, 2, 3 and 8 showed antibacterial activities against X. oryzae pv. oryzicola Swings and E. amylovora with the same MIC values of 20μg/mL while 10 exhibited activities against E. amylovora with an MIC value of 10μg/mL.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Yan W,Wuringege,Li SJ,Guo ZK,Zhang WJ,Wei W,Tan RX,Jiao RH

doi

10.1016/j.bmcl.2016.11.033

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

51-54

issue

1

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(16)31176-3

journal_volume

27

pub_type

杂志文章

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