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Stability studies of ascorbic acid 2-glucoside in cosmetic lotion using surface response methodology.

Abstract：

:Ascorbic acid 2-glucoside (AA-2G) has been widely used in cream and lotion types of cosmetic products. Thus, the degradation of AA-2G caused by the temperature change and pH variation was very critical for determining the bio-functionality of cosmetics. Response surface methodology (RSM) was introduced to study the influence of temperature and pH on the stability of AA-2G. The optimal condition of retaining AA-2G with the highest stability was determined to be 55.3°C and pH 6.4. The antioxidative activities of AA-2G including DPPH and ABTS free radical scavenging activities, metal chelating activity, and reducing ability were also determined. AA-2G was a good ascorbic acid derivative which could be used in cosmetic products as an active ingredient.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Huang WY,Lee PC,Huang LK,Lu LP,Liao WC

doi

10.1016/j.bmcl.2013.01.111

subject

Has Abstract

pub_date

2013-03-15 00:00:00

pages

1583-7

issue

6

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(13)00144-3

journal_volume

23

pub_type

杂志文章

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