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Neural and behavioral suppression of interfering flankers by children with and without autism spectrum disorder.

Abstract：

:Electrophysiological responses, accuracy and reaction time were recorded while 7-11-year-olds with typical development (TYP; N=30) and autism spectrum disorder (ASD; N=19) inhibited conflicting information. Relative to the TYP group, children with ASD had larger decrements in accuracy for incongruent trials and were slower. In terms of neural responses, N2 mean amplitude was greater overall for children with ASD relative to TYP children. N2 neural responses related to a behavioral measure of inhibition and cognitive flexibility for TYP children, whereas it related to suppression of interfering information and maintenance of accurate responding for the children with ASD. Results suggest children with ASD recruit more neural resources and perform worse when inhibiting conflicting information relative to TYP peers.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Faja S,Clarkson T,Webb SJ

doi

10.1016/j.neuropsychologia.2016.10.017

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

251-261

issue

Pt A

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(16)30391-8

journal_volume

93

pub_type

杂志文章

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