Abstract：
:To measure retinal nerve fiber layer (NFL) thickness, three sets of simultaneous stereophotographs of the optic disc, taken with the Donaldson fundus camera, were measured at 5 degrees intervals in a stereoplotter (Kern PG2) at the surface of the internal limiting membrane (ILM) and the retinal pigment epithelium (RPE) along the disc margin. The NFL thickness was expressed as a ratio of the vertical disc radius. The reproducibility of the method showed that the percent coefficients of variation (CV%) for 15 normal, 10 ocular hypertensive, and 10 glaucomatous subjects were 5.2%, 6.0%, and 3.9%, respectively. The presence of a halo or scleral crescent had no significant effect on reproducibility. The photogrammetric technique for measuring NFL thickness appears to be highly reproducible and sensitive and may be a valuable quantitative method for: (1) early detection of optic nerve damage from glaucoma and other optic neuropathies and (2) monitoring progression of retinal NFL defects.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Takamoto T,Schwartz Bdoi
10.1016/s0161-6420(89)32720-5subject
Has Abstractpub_date
1989-09-01 00:00:00pages
1315-9issue
9eissn
0161-6420issn
1549-4713pii
S0161-6420(89)32720-5journal_volume
96pub_type
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