Abstract：
INTRODUCTION:The prognosis of patients diagnosed with metastatic prostate cancer seems to be modulated by factors such as the number and site of metastases. Our objective is to evaluate survival outcomes according to the number and site of metastases in our series of metastatic patients over the last 15 years. MATERIALS AND METHODS:A retrospective analysis was performed on patients diagnosed between 1998 and 2014. We analyzed overall survival and progression-free survival, depending on the number and location of metastases on patients with newly diagnosed metastatic prostate cancer. Other potential prognostic factors were also evaluated: age, clinical stage, PSA at diagnosis, Gleason, PSA nadir, time till PSA nadir and first-line or second-line treatment after progression. RESULTS:We analyzed a series of 162 patients. The mean age was 72.7yr (SD: 8.5). The estimated median overall survival was 3.9 yr (95% CI 2.6-5.2). The overall survival in patients with only lymph node metastases was 7 yr (95% CI 4.1-9.7), 3.9 (95%CI 2.3-5.5) in patients with only bone metastases, 2.5 yr (95% CI 2-2.3) in lymph nodes and bone metastases, and 2.2 yr (95% CI 1.4-3) in patients with visceral metastases (P<.001). In multivariate analysis, the location of metastasesis significantly associated with overall survival and progression-free survival. The number of metastases showed no association with survival. CONCLUSIONS:The site of metastases has a clear impact on both overall survival and progression-free survival. Patients with only lymph node involvement had a better prognosis. The number of metastases showed no significant impact on survival in our series.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Guijarro A,Hernández V,de la Morena JM,Jiménez-Valladolid I,Pérez-Fernández E,de la Peña E,Llorente Cdoi
10.1016/j.acuro.2016.09.004subject
Has Abstractpub_date
2017-05-01 00:00:00pages
226-233issue
4eissn
0210-4806issn
1699-7980pii
S0210-4806(16)30134-6journal_volume
41pub_type
杂志文章abstract：:Fifty-one patients with non-seminoma testicular cancer who underwent retroperitoneal ganglion dissection and 3 support cycles of chemotherapy with Cys-Platin, Vinblastine and Bleomycin. Four patients presented relapses (7.8%). Actuarial survival by 8 years was 87%, with a median of 38 months. The median survival was 4...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Granulomatous orchitis is an inflammatory change of the testis. This is a rare lesion of unknown etiology. Usually are unilateral. The clinical appearance varies, and it is difficult to differentiate from testicular cancer. The diagnosis usually being made on histological examination after orchiectomy. Our paper repor...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72526-5
更新日期：2000-09-01 00:00:00
abstract：:Presentation of one case of penis-located multiple skin metastasis from prostate adenocarcinoma after hormonal blockade for 11 years. Revision and update of the topic, corroborating the poor prognosis of these patients. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:To perform a multivariate statistical analysis of epidemiological, clinical and biochemical factors that make it possible to identify the variables that can independently predict the course of renal lithiasis, thus defining a group at risk of worse evolution. MATERIAL AND METHODS:A retrospective, descriptive...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2011.09.004
更新日期：2012-06-01 00:00:00
abstract：UNLABELLED:Pelvic physical therapy focuses on the prevention and the treatment of all kinds of functional disorders of the abdominal, pelvic and low back region, like urinary incontinence, that is considered as a high prevalent health problem in women, men, children and the elderly. Physical therapy is often considered...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73412-x
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE:To assess the expectant management superficial recurrent bladder tumours. MATERIAL AND METHODS:Between Jan 1998 and Dec 2003, 112 patients were diagnosed of superficial bladder tumour. 13 patients were observed after the diagnosis of tumour relapse until the decision to perform a transurethral resection. We ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73298-8
更新日期：2005-06-01 00:00:00
abstract：:Presentation of a malignant rhabdoid renal tumour. This type of sarcoma which occurs commonly during the paediatric age is exceptional in the adult, this being the reason for reviewing this clinical case and its management. The term rhabdoid includes several types of morphologically similar tumours which make analysis...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:To review the outcome of bulbar urethroplasty using two stage surgical techniques. MATERIAL AND METHODS:Twenty-two of the 35 patients studied corresponded to end-to-end urethroplasty (ATT) and 13 to dorsal onlay graft (DOG) in preputial skin or oral mucosa variants. Clinical outcome was considered a failure ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2012.03.006
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:To assess the safety of hospital discharge 24 hours after laparoscopic radical prostatectomy and to identify possible factors associated with longer hospital stays. MATERIAL AND METHODS:Retrospective study of patients diagnosed with localized prostate cancer underwent to laparoscopic radical prostatectomy co...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2013.12.004
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To analyse the value of a second transurethral resection, repeated within 3 to 6 weeks after the initial resection, in the treatment and the classification of patients with bladder tumour. MATERIAL AND METHODS:We analyse the results of 72 repeated transurethral resection in 23 (32%) patients with T1 G1-2 bla...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(01)72596-x
更新日期：2001-03-01 00:00:00
abstract：:Long-term results obtained in 54 surgical procedures to correct effort urinary incontinence performed in 49 patients with this pathology are reviewed. One group was treated with suprapubic urethrovesical suspension with the Marshall-Marchetti-Krantz technique; the other group with endoscopic suspension of the neck of ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:Inflammation has been implicated as an etiological factor in different human cancers. Allelic variations in the genes implicated in inflammation are candidates as genetic determinants or markers of renal carcinoma risk. The present stud investigates whether polymorphisms of the genes that give rise to increases in the...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)74180-4
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:It is aimed to characterize the true relationship of the cold ischemia time (CIT) with graft survival and with the principal post-transplantation events. MATERIAL AND METHODS:We analyzed 378 kidney transplants, studying the relationship of the CIT with graft survival using a univariate analysis according to ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2011.03.005
更新日期：2011-09-01 00:00:00
abstract：:This article reviews the current status of the prostatic cryosurgery in the management of patients with prostate cancer. Recent advances in cryoablative technology have allowed to treat these patients successfully with decreased morbidity. Using transrectal high-resolution ultrasound imaging, prostate cryotherapy is d...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(07)73627-6
更新日期：2007-03-01 00:00:00
abstract：:Prostate carcinoma is diagnosed in earlier phases of its evolution, but this carcinoma may have an unpredictible evolution. Radical treatment (surgery and radiotherapy) is the best treatment in clinically localized tumors. The biochemical failure over 5 years from the surgery is 20-50% of the patients; the biochemical...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)72987-8
更新日期：2003-09-01 00:00:00
abstract：:Inverted papilloma is a rare tumour (2.2% of urothelial tumours) considered to be benign. The bladder is the most frequent site and growth tends to be endophytic towards the submucosa. Haematuria and obstruction symptoms appear to be the most typical clinical manifestations. Contribution of two cases of inverted bladd...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(00)72474-0
更新日期：2000-05-01 00:00:00
abstract：OBJECTIVES:To study the technical opinion of an expert panel and reach a consensus of professional criterion in relation to the most recent scientific evidence in Benign Prostatic Hyperplasia (BPH) in the scopes of diagnosis, progression criteria, medical treatment and surgical treatment. MATERIAL AND METHODS:Systemat...
journal_title：Actas urologicas espanolas
pub_type： 共识发展会议,杂志文章,评审
doi：10.1016/j.acuro.2012.01.004
更新日期：2012-05-01 00:00:00
abstract：CONTEXT:Cervical cancer is the second most common tumor in women worldwide and due to diagnostic and therapeutic advances, the overall survival rates at 5 years is approaching 70%. Disorders in micturition, defecation, sexuality and quality of life have been described, frequently caused by different treatments. Address...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2012.03.008
更新日期：2013-01-01 00:00:00
abstract：:Between 1975-1991, a total of 557 cases of bladder carcinoma were identified in the Autonomous Community of La Rioja (CAR) which were followed up to December 1994. The overall lethality was 21.9%. 492 cases with 22.35% lethality were identified in males. In females, however, there was 65 cases with 18.46% lethality. T...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：INTRODUCTION:Urolithiasis is a disease having a high recurrence rate and associated morbidity. A not well quantified increase is being seen in recent years that could be related with various factors. The main purpose of our study has been to estimate urolithiasis prevalence and incidence in the region of Andalusia, det...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.02.006
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To communicate long-term results of the multicentre phase III trial post-prostatectomy urinary incontinence (PPI) treated with an adjustable male sling. PATIENTS AND METHODS:48 PPI patients were included in this trial from April 2003 to September 2004. 39 post radical prostatectomy and 9 post adenomectomy. 1...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/s0210-4806(09)74146-4
更新日期：2009-03-01 00:00:00
abstract：:Case report of a patient bearer of a double-J ureteral catheter due to ureteral lithiasis. After persistent renoureteral pain and fever, the proximal migration of the catheter is confirmed radiologically. The predisposing factors for this complication, described in the literature, are reviewed. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVES:The testicular tumors are frequent in the young adult, coinciding with the incorporation to the Military Service. The objective of our work is to evaluate the tumoral characteristic, its evolution with the time and the result of the treatments used in our center for this type of tumors. MATERIAL AND METHODS...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73275-7
更新日期：2005-05-01 00:00:00
abstract：:Contribution of two cases of congenital adrenal hyperplasia by blockade in the 21-hydroxylase enzyme synthesis. Diagnosis was reached from the clinical signs and symptoms (virilization syndrome), and was confirmed by radiological and laboratory tests. Hormone treatment was done with hydrocortisone and fludrocortisone,...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：INTRODUCTION:The prostate cancer is an important cause of men's mortality in our society. PURPOSE:To know the time of delay in to realise the surgical treatment of the prostate cancer. MATERIALS AND METHODS:Analysis of 30 cases of patients treated with radical prostatectomy, cuantifying the time of delay in all the p...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(03)72922-2
更新日期：2003-04-01 00:00:00
abstract：INTRODUCTION:Gleason score biopsy undergrading (GSBU) can have an impact on the management and prognosis of patients with prostate cancer. We analyze the possible impact of time and other clinical and analytical factors in the appearance of GSBU in our series. PATIENTS AND METHOD:Ambispective, multicenter study of 195...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2019.08.004
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION:Laparoscopic adenomectomy is a feasible and effective surgical procedure. We have progressively simplified the procedure using barbed sutures and a technique we call "knotless" laparoscopic adenomectomy. We present a prospective, multicenter, descriptive study that reflects the efficacy and safety of this ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.05.011
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:Delayed graft function alter living donor transplantation is a subject of debate. Delayed graft function can be partially explained by renal ischemia-reperfusion injury, when severe is associated with decreased graft survival. In this experimental living donor model study, we analyze the hemodynamic, histo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(08)73802-6
更新日期：2008-01-01 00:00:00
abstract：:We report a case of necrotizing granulomatous vasculitis in the spermatic cord in a 35-year-old man with an antecedent of brain stroke 3 years before. The clinical manifestation was as a painless left scrotal mass. The diagnosis was established by histological examination of the spermatic cord. We discuss the physical...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73340-4
更新日期：2005-09-01 00:00:00
abstract：RATIONALE:To investigate whether, in the same way incidence is affected, biological aggressiveness of bladder cancer at diagnosis is greater in men than in women. METHOD:Using data from a retrospective study on urothelial cancer of the bladder between 1975 and 1991 in La Rioja (Spain), an estimate was made of total Re...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
