[Is there a safe cold ischemia time interval for the renal graft?].

Abstract:

OBJECTIVE:It is aimed to characterize the true relationship of the cold ischemia time (CIT) with graft survival and with the principal post-transplantation events. MATERIAL AND METHODS:We analyzed 378 kidney transplants, studying the relationship of the CIT with graft survival using a univariate analysis according to the COX model and seeking the optimum cutoff according to the Kaplan-Meier method and log-rank test. The relationship between CIT and the principal events of the post-transplant was studied using the binary logistic regression. RESULTS:The mean follow-up of all the group was 77.8 months (± 51 SD) and the mean CIT was 14.8 hours (± 5.1 SD). The univariate analysis revealed that the CIT was not related with the graft survival as a continuous variable (OR=1.04; 95% CI: 0.9-1.08; p>0.05). On establishing the cutoff at 18 hours, we found differences in the actuarial survival. Survival at 5 years was 91% with CIT < 18 h versus 84% with CIT >18 h. Each hour of cold ischemia increased risk of delay in the graft function by 10% (OR=1.1; 95% CI: 1.05-1.15; p<0.001) and also conditioned a greater incidence of acute rejection (41.5% vs. 55.3%; p=0.02) and less time to the first rejection episode (72.6 days±137 vs. 272.2 days±614.8; p=0.023) after 18 hours. The CIT did not seem to be related (p<0.05) with the rest of the post-transplantation events, such as surgical complications or hospital admissions. CONCLUSIONS:In our experience, cold ischemia under 18 hours does not seem to negatively affect graft survival.

journal_name

Actas Urol Esp

authors

Barba J,Zudaire JJ,Robles JE,Tienza A,Rosell D,Berián JM,Pascual I

doi

10.1016/j.acuro.2011.03.005

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

475-80

issue

8

eissn

0210-4806

issn

1699-7980

pii

S0210-4806(11)00126-4

journal_volume

35

pub_type

杂志文章
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    doi:

    authors: Villavicencio H,Parra L,Ruiz Castañé E

    更新日期:1989-11-01 00:00:00

  • [Malignant rhabdoid tumor of the kidney in the adult].

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    doi:

    authors: Caballero JM,Collera P,Marti L,Borrat P,Hoyuela C,Rodríguez Santiago J,Ristol J

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    journal_title:Actas urologicas espanolas

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    doi:

    authors: Montes Díaz MJ,Fernández González I,Llorente Abarca C,Ruiz Rubio JL,Herrero Payo A,Romero Cagigal I,Berenguer Sánchez A

    更新日期:1994-07-01 00:00:00

  • [Clinico-pathologic correlation in patients undergoing surgical staging and radical prostatectomy for prostatic cancer].

    abstract::Presentation of our experience on the clinico-pathological staging of clinically localized prostate cancer (PCa) in 38 patients undergoing staging lymphadenectomy, 34 of which were treated with radical prostatectomy. From total number of patients, 37% were correctly staged, 60% were under-staged and only 3% were over-...

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    doi:

    authors: Isa Kroon WA,De Castro Barbosa F,Abad Vivas-Perez JI,Robles García JE,Zudaire Bergera JJ,Berián Polo JM

    更新日期:1993-02-01 00:00:00

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    abstract:OBJECTIVES:Traditionally, urine cytology has been considered as the gold standard for bladder cancer screening. However, new methods are playing new roles in these cases. In order to assess the value of cytology of voided urine we performed one comparative study between cytology and biopsy. METHODS:We retrospectively ...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

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    authors: Garcia Castro M,Fernández Fernández E,Martín Corriente MC,Garcia Hernández S,Alvarez-Argüelles CH

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  • [Emphysematous cystitis].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:

    authors: Calahorra Fernández FJ,Díaz González R,Pamplona M,Rodríguez A,Castro MA,Passas J,Leiva O

    更新日期:1989-09-01 00:00:00

  • [Cryosurgery in the management of prostate cancer].

    abstract::This article reviews the current status of the prostatic cryosurgery in the management of patients with prostate cancer. Recent advances in cryoablative technology have allowed to treat these patients successfully with decreased morbidity. Using transrectal high-resolution ultrasound imaging, prostate cryotherapy is d...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:10.1016/s0210-4806(07)73627-6

    authors: Pontones Moreno JL,Morera Martínez JF,Vera Donoso CD,Jiménez Cruz JF

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  • [Renal cell carcinoma presenting as paraneoplastic neurological dysfunction].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(08)73902-0

    authors: Hens MJ,Camacho B,Maestre A,González V,Villegas I,Magaña M

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  • High-dose rate brachytherapy as monotherapy in prostate cancer: A systematic review of its safety and efficacy.

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

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    journal_title:Actas urologicas espanolas

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  • [Influence of sex differences in biological aggressivity of bladder urothelial tumor at first diagnosis].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Fernández Fernández A,García Escudero C,Fernández Ruiz M,Domínguez Benito P,Gil Fabra J,Otero Mauricio G

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  • [Transperitoneal laparoscopic partial nephrectomy in the renal tumor treatment].

    abstract::Laparoscopic surgery is a surgical technique the urologist should add to his surgical armamentarium. Its performance tries to mimic the surgical phases of open surgery, and also its indications. Laparoscopic partial nephrectomy is a sophisticated technique that requires wide experience in the performance of endoscopic...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(06)73486-6

    authors: Rosales Bordes A,Salvador Bayarri J,de Graeve N,Palou Redorta J,Villavicencio Mavrich H

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  • [Reference values of prostate specific antigen (PSA) in 63926 workers without prostatic symptoms who participated in prostate screening cancer developed by the Ibermutuamur Prevention Society in 2006].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,多中心研究

    doi:

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

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  • [Acute focal bacterial nephritis in a case of AIDS].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Angulo JC,Loizaga A,de Garay MG,Flores N

    更新日期:1993-01-01 00:00:00

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/j.acuro.2015.10.004

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    更新日期:2016-05-01 00:00:00

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

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  • [Clinical features, diagnosis, and prognosis of renal carcinoma].

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    pub_type: 杂志文章,评审

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    更新日期:2002-09-01 00:00:00

  • [Prostatic calculi: silent stones].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

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    更新日期:2010-06-01 00:00:00

  • [Bladder hemangioma: a clinical case].

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:

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    更新日期:1997-05-01 00:00:00

  • [Cystadenoma of seminal vesicles].

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    pub_type: 杂志文章,评审

    doi:

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    doi:

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  • [Endoscopic cystolithotomy: hypogastric approach].

    abstract::Vesical lithiasis is a relatively frequent problem, the solution of which has changed over the last few years driven by major technological evolution. Traditional open surgery has been outstaged by the new endoscopic techniques and extracorporeal lithotrity. Here, we present our endoscopic resolution protocol through ...

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    pub_type: 临床试验,杂志文章

    doi:

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  • [Varicocele: personal contributions to the surgical technique].

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    pub_type: 杂志文章,评审

    doi:

    authors: Bayo Ochoa A

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  • [Bladder endometriosis. Diagnostic and therapeutic approximation].

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    pub_type: 杂志文章

    doi:

    authors: Monllor Gisbert J,Merino Hernaez C,Olivier Gómez C,Carballido Rodríguez J

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