Abstract：
CONTEXT:High-dose rate brachytherapy (HDR-BT) is an increasingly popular treatment for patients with localised prostate cancer (PC). OBJECTIVE:To assess the safety and efficacy of HDR-BT as monotherapy in PC. ACQUISITION OF EVIDENCE:A systematic literature review was conducted through searches on MEDLINE (PubMed), Cochrane Library, CDR, ClinicalTrials and EuroScan. We assessed safety and efficacy indicators. SUMMARY OF THE EVIDENCE:We selected 2 reviews and 12 uncontrolled studies, included in these 2 reviews. In terms of efficacy, local control in 6 studies was 97-100%. The biochemical progression-free survival varied as follows: 85-100% for low risk and 79-92% for high risk. Survival free of metastases was >95% at 8 years, except in one study where the survival rate was 87% at 5 years. The overall survival was ≥95% in 8 studies. In terms of safety, most of the studies recorded acute and long-term genitourinary and gastrointestinal complications, especially grade ≥2. Only 3 studies found grade 4 complications. All studies, except for one without complications, observed genitourinary complications that were more frequent and severe than the gastrointestinal complications. Two studies assessed the quality of life and showed an initial reduction in various domains and subsequent partial or total recovery, except in the sexual domain. CONCLUSIONS:HDR-BT is effective as monotherapy, especially in cases of low to intermediate risk. There is insufficient information on high-risk patients. The short to medium-term toxicity was acceptable. Further research needs to be funded to provide more information on the long-term safety and efficacy of this treatment.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Sánchez-Gómez LM,Polo-deSantos M,Rodríguez-Melcón JI,Angulo JC,Luengo-Matos Sdoi
10.1016/j.acuro.2016.06.001subject
Has Abstractpub_date
2017-03-01 00:00:00pages
71-81issue
2eissn
0210-4806issn
1699-7980pii
S0210-4806(16)30101-2journal_volume
41pub_type
杂志文章,评审abstract：INTRODUCTION:Malignant tumors sometimes initiate as paraneoplastic syndromes even years before the most common symptoms appear. These first manifestations could be the key for the diagnosis of "occult" malignancy. METHODS:We report the case of a 66 year old man with a renal cell carcinoma. The first symptom was a para...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73902-0
更新日期：2008-06-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:Prostate stones are frequently encountered during transurethral resection of the prostate in urology practice. We aimed to demonstrate the physical and chemical properties of prostate stones. We also aimed to determine possible relationship between inflammation of prostate gland and prostate...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:San Antonio, Somacarrera (1977) and Rousaud-Inmark (1984) studies established the first data of incidence and prevalence about urolithiasis in Spain. Other regional or national epidemiologic details were given for several authors from 1977 to 2002. MATERIAL AND METHOD:Sixteen papers with original data abo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(07)73675-6
更新日期：2007-05-01 00:00:00
abstract：:Patient treated by dialysis for end-stage renal disease are at increased risk of many cancers, especially those of kidney and urinary tract. A 56 years old man who undergoing chronic dialysis, presented in ultrasonography a 2 cm complex cystic mass in the left kidney what was confirmed by computed tomography and magne...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73884-1
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:The prostate cancer is an important cause of men's mortality in our society. PURPOSE:To know the time of delay in to realise the surgical treatment of the prostate cancer. MATERIALS AND METHODS:Analysis of 30 cases of patients treated with radical prostatectomy, cuantifying the time of delay in all the p...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(03)72922-2
更新日期：2003-04-01 00:00:00
abstract：UNLABELLED:In order to make a measure of quality of life related to health (QLRH) useful in the investigation, it must fulfill the psychometric properties (validity, reliability and sensibility). The selection of an instrument is a job for the clinic that must choose the most effective for each proposed objective. We s...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/s0210-4806(02)72784-8
更新日期：2002-05-01 00:00:00
abstract：INTRODUCTION:Bladder cancer is a disease with a high prevalence due to its recurrence rate. Transurethral resection of the bladder (TURB) is the treatment in initial stages. Nevertheless, a high percentage of non-muscle-invasive tumors treated will have a recurrence 1-2 years afterwards. Adjuvant quemotherapy or immuno...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,随机对照试验
doi：10.1016/s0210-4806(08)73940-8
更新日期：2008-09-01 00:00:00
abstract：:As a result of finding some ectopic adrenal debris in the spermatic cord, the present report studies the embryogenesis and clinical implications that can derive from the existence of the referred adrenal debris. The relevant literature is reviewed and six new cases contributed, one of them bilateral. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：PURPOSE:Pulsed dye laser lithotripsy has shown to be an effective and safe procedure for treatment of ureteral calculi. We report our experience. MATERIAL AND METHODS:A total of 1000 patients were treated with pulsed dye laser between January 1990 and February 1996. In 450 patients the procedure was performed under ge...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:In renal transplant patients, an increased risk of cancer has been seen, higher than in the general population, and the more frequent genitourinary neoplasms are the kidney and bladder ones. Moreover, in those patients the pattern of tumor growth is very rapid, with early tendency to local and systemic dissemination. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72426-0
更新日期：2000-02-01 00:00:00
abstract：BACKGROUND:To evaluate the diagnostic usefulness of the cytological study of the transport buffer in the diagnosis of prostate adenocarcinoma in transrectal core biopsies. METHODS:A total of 256 consecutively biopsied patients have been included in the analysis, 100 of them diagnosed of prostate adenocarcinoma. The pr...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.01.003
更新日期：2014-11-01 00:00:00
abstract：:PSA is, currently, the best marker to detect prostatic changes, although it looses specificity when used in the differential diagnosis of certain pathologies of the prostate gland. Forty-four patients with benign prostate hyperplasia were analyzed and 26 (59%) of them were found to have higher than normal PSA levels. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：:We report a case of a presacral benign schwannoma which causes right hydroureteronephrosis without other clinical findings. After a fine-needle aspiration (FNA) biopsy under computed tomography (CT) guidance, a fusocellular tumour without athypia was demonstrated. With the initial diagnosis of benign schwannoma the pa...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(01)72606-x
更新日期：2001-03-01 00:00:00
abstract：:During the first ten years (1981-1990) of our organ transplantation program a total of 395 Renal Transplants (RTx) have been carried out in our Unit, 90 of which in 88 patients had to be subsequently transplantectomized. In 32 of them the reason was acute rejection (35%) including 7 renal rhexis, and in 30 chronic rej...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Treatment of infiltrant vesical cancer has traditionally been the grounds for intense controversy. Transurethral resection (TUR) followed by high voltage radiotherapy (RT) in selected cases of locally advanced vesical urothelial tumours can be a valid alternative for the treatment of this condition. This paper disclos...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：GOALS:To estimate the prevalence, age distribution, impact on quality of life and type of urinary incontinence (UI) in women over 30 years in Mallorca (Spain). MATERIAL AND METHODS:Cross-sectional descriptive study on a randomized sample of 673 women in the health district affiliated to Son Llàtzer Hospital and the 14...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2012.11.004
更新日期：2013-06-01 00:00:00
abstract：:We report the case of a 26 years old female who presented, as a casual finding, a right complete ureteral triplicity (probably Campbell's tipe I) with no other associated abnormalities. Despite ureteral duplication is a frequent urological anomaly, the presence of three ureters occurring in the same side, in a complet...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(04)73179-4
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:To determine the diagnostic performance of extended prostatic biopsy (PB) in prostate cancer (PC) and variables affecting positivity. MATERIALS AND METHODS:Patients (n = 147) underwent 24 cylinder PB at the Arquitecto Marcide Hospital, Ferrol, La Coruña, between December 2002-September 2004. Inclusion criter...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73373-8
更新日期：2005-11-01 00:00:00
abstract：:The incidence of renal anomalies in patients who suffer a renal trauma is around 4.4 and 19%. We introduce a case of a patient whose first sign of a chronic hydronefrosis was a renal burst secondary to an abdominal trauma. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.4321/s0210-48062007000800019
更新日期：2007-09-01 00:00:00
abstract：UNLABELLED:Pelvic physical therapy focuses on the prevention and the treatment of all kinds of functional disorders of the abdominal, pelvic and low back region, like urinary incontinence, that is considered as a high prevalent health problem in women, men, children and the elderly. Physical therapy is often considered...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73412-x
更新日期：2006-02-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：CONTEXT:Interest in having alternatives in the treatment of benign prostate hyperplasia. OBJECTIVES:To assess the efficacy and safety of the Urolift® system for treating the symptoms of benign prostate hyperplasia. ACQUISITION OF EVIDENCE:Systematic review of the literature through searches on PubMed, Cochrane Librar...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2014.05.010
更新日期：2015-06-01 00:00:00
abstract：:Retrocaval ureter is a rare disease in childhood which is due to a abnormal development of the inferior cava vein. We report a new case of retrocaval ureter in a 9 year-old girl who had consulted for macrohematuria and right flank pain. Preoperative intravenous urography and DTPA diuretic renogram suggested this entit...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to determine which cancer and demographic criteria influence the indication for surgery (radical prostatectomy) or radiation therapy (external or brachytherapy) in the treatment of prostate cancer. MATERIAL AND METHODS:An analysis of the 2714 patients of the 2010 National Prostate Ca...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2016.04.011
更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:primary hyperaldosteronism is one of the few potentially curable causes of secondary arterial hypertension. One of the most important variants is the adenoma of the adrenal cortex that produces aldosterona (Conn's Syndrome). The treatment of choice in this subgroup of patients was the removal of the lesion...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2010.11.009
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:To assess the expectant management superficial recurrent bladder tumours. MATERIAL AND METHODS:Between Jan 1998 and Dec 2003, 112 patients were diagnosed of superficial bladder tumour. 13 patients were observed after the diagnosis of tumour relapse until the decision to perform a transurethral resection. We ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73298-8
更新日期：2005-06-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:There is no high-level evidence as to which primary treatment provides an overall survival (OS) or cancer-specific survival (CSS) advantage in high-risk localised prostate cancer (HRLPC). Our aim was to analyse the differences in survival and predictive factors in this group of patients, acc...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2018.06.006
更新日期：2019-03-01 00:00:00
abstract：:Vesical leiomyoma is a benign mesenchymal tumor that rarely involves the bladder and makes about 1.5% of all vesical tumors. A new case is presented and aspects concerning clinical, diagnostic and surgical issues are examined. The paper includes a revision of the available literature on the topic. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：OBJECTIVE:It is aimed to characterize the true relationship of the cold ischemia time (CIT) with graft survival and with the principal post-transplantation events. MATERIAL AND METHODS:We analyzed 378 kidney transplants, studying the relationship of the CIT with graft survival using a univariate analysis according to ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2011.03.005
更新日期：2011-09-01 00:00:00
abstract：INTRODUCTION:Laparoscopic adenomectomy is a feasible and effective surgical procedure. We have progressively simplified the procedure using barbed sutures and a technique we call "knotless" laparoscopic adenomectomy. We present a prospective, multicenter, descriptive study that reflects the efficacy and safety of this ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.05.011
更新日期：2015-03-01 00:00:00
