Abstract：
INTRODUCTION:Gleason score biopsy undergrading (GSBU) can have an impact on the management and prognosis of patients with prostate cancer. We analyze the possible impact of time and other clinical and analytical factors in the appearance of GSBU in our series. PATIENTS AND METHOD:Ambispective, multicenter study of 1955 patients with localized prostate cancer undergoing radical prostatectomy between 2005 and 2018. Descriptive statistics and hypothesis testing are reported by univariate and multivariate analyses. RESULTS:Mean age 63.69 (44-80) years, median PSA 8.70 ng / ml (1.23-99). GSBU was observed in 34.7% of the entire cohort. In 72.8% of the cases, the GSBU occurred in one consecutive Gleason score, with the progression from 3 + 3 to 3 + 4 being the most frequent (289 patients, 47.6%). Performing radical prostatectomy 90-180 days before or after the biopsy does not have an impact on its undergrading in any of the groups. In the univariate and multivariate analysis, the presence of tumor or pathological rectal examination in both lobes, the tumor load ≥50% of cylinders and a DPSA ≥0.20, showed independent discriminative capacity to select patients who presented GSBU. CONCLUSIONS:The time from biopsy to radical prostatectomy did not show impact on GSBU. The number of affected cylinders, bilateral tumor and DPSA are easily accessible parameters that can help us select patients with greater probability of presenting GSBU.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Virseda Rodríguez AJ,Marcos Asensio S,Herrero Polo M,Hernández Sanchez T,Sanz Ruiz A,García F,Vesga F,Gutiérrez E,Serrano JM,Calleja J,Cortiñas JR,Zamora A,Rodríguez V,Amon Sesmero JH,Szczesniewski RJ,Valverde Martínez S,doi
10.1016/j.acuro.2019.08.004subject
Has Abstractpub_date
2020-04-01 00:00:00pages
187-195issue
3eissn
0210-4806issn
1699-7980pii
S0210-4806(19)30164-0journal_volume
44pub_type
杂志文章abstract：:We present a fresh case of Pelvic Lipomatosis in a non obese young male. We comment on the suggestive radiological findings as well as on the therapeutic options. Although considered traditionally as a benign entity, it may cause serious physiopathological alterations in neighbouring organs. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：:Retrocaval ureter is a rare disease in childhood which is due to a abnormal development of the inferior cava vein. We report a new case of retrocaval ureter in a 9 year-old girl who had consulted for macrohematuria and right flank pain. Preoperative intravenous urography and DTPA diuretic renogram suggested this entit...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION:NF-kB (p50/p65) is a transcription factor involved in TNF-α-induced cell death resistance by promoting several antiapoptotic genes. We intend to relate the expression of NF-kB (p50 and p65) with serum levels of prostate-specific antigen (PSA), both in normal males and in those with pathologic conditions of...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2010.08.002
更新日期：2011-01-01 00:00:00
abstract：:Significant conceptual changes have taken place in renal tumoral diseases over the last few years. As a result of the authors' broad institutional experience, this overall revision describes the most up-to-date clinical and diagnostic aspects of this condition. Emphasis is made on molecular staging and two variables t...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(02)72825-8
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:To determine the current state of vesicouterine fistulae in our hospital, the factors associated with their development and the findings obtained from the treatments used. MATERIAL AND METHODS:We carry out a retrospective study on a group of patients suffering from vesicouterine fistulae who were treated in ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)73000-9
更新日期：2003-10-01 00:00:00
abstract：CONTEXT:Bladder carcinoma (BC), due its high morbidity and relapsing course, generates significant economic and health care costs. Accordingly, review the environmental nonoccupational risk factors (RF), more or less evidence-based, in the etiology and pathogenesis of BC, because the involvement of urologists is essent...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2013.02.004
更新日期：2013-10-01 00:00:00
abstract：:From November 1987 treatment of urinary lithiasis regardless location was initiated in our Service of extracorporal renal lithofragmentation using shockwaves. Up until August 1988 (10 months), 411 patients have been treated representing a total of 590 lithiasis and 699 sessions on which the present communication is ba...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：:Cystadenoma of the seminal vesicles is a extremely rare pathology. To our knowledge only eight cases have been reported in the literature. We report a new case of this benign tumor, bilaterally located and incidentally found at surgery. Literature is reviewed and clinical, diagnostic and therapeutic aspects of these a...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1997-06-01 00:00:00
abstract：UNLABELLED:Pelvic physical therapy focuses on the prevention and the treatment of all kinds of functional disorders of the abdominal, pelvic and low back region, like urinary incontinence, that is considered as a high prevalent health problem in women, men, children and the elderly. Physical therapy is often considered...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73412-x
更新日期：2006-02-01 00:00:00
abstract：:Benign prostatic hypertrophy (BPH) is a common urological disease with a standard surgical approach, transurethral resection (TUR) or open adenectomy (OA), but the flowmetric clinical results are controversial. Fifty-five patients were evaluated; in 23 of them TUR was performed and 32 underwent OA. The Boyarsky clinic...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章,评审
doi：
更新日期：1994-07-01 00:00:00
abstract：:Prostate carcinoma is diagnosed in earlier phases of its evolution, but this carcinoma may have an unpredictible evolution. Radical treatment (surgery and radiotherapy) is the best treatment in clinically localized tumors. The biochemical failure over 5 years from the surgery is 20-50% of the patients; the biochemical...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)72987-8
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:Renal haematomas after extracorporeal shockwave lithotrity are an immediate and potentially serious complication. The incidence of post-ESWL renal haematoma with the new Siemens' Lithostar Multiline lithotripter is analyzed in an attempt to know its occurrence, predisposing factors and presentations signs and...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72399-0
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To perform a comparative analysis of indirect and direct costs of two minimally invasive techniques (extracorporeal shock wave lithotripsy (ESWL) vs. ureteroscopy with holmium laser (URS/RIRS)) for the treatment of renal/ureteral calculi smaller than 2 cm. MATERIAL AND METHODS:Prospective, comparative, non-r...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2020.03.008
更新日期：2020-09-01 00:00:00
abstract：:Contribution of one case report of papillary cystadenoma, a very uncommon benign epithelial tumour. Related to von Hippel-Lindau's disease, it may be associated to infertility. It tends to occur in young adults, lesions being bilateral in one third of cases. It is diagnosed through palpation and particularly with ultr...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72541-1
更新日期：2000-10-01 00:00:00
abstract：:Review of 158 cases of renal traumatism attended ar the Urology Service of "La Fe" Hospital from 1984 to 1995. We analyze the indications of radiological study of the polytraumatized patient, the different classifications of renal traumatism and the changes produced in the diagnosis protocol, after substituting urogra...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：INTRODUCTION:Renal angiomyolipomas are not very frequent in urologic activities. Pulmonary lymphangioleiomyomatosis is a rare disease that occurs mainly in women of reproductive age. Tuberous sclerosis shows lesions to different organs, including these both entities. MATERIAL AND METHOD:We retrospectively analyze pati...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(06)73462-3
更新日期：2006-04-01 00:00:00
abstract：UNLABELLED:Orthotopic renal transplant (ORT) is useful in cases of severe atherosclerosis, heterotopic bilateral transplant, unsuitable pelvic vessels and in aortic thrombosis, but it is not available in all the institutions and it is only realized of exceptional form. AIM:To review the indication, surgical technique ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(07)73774-9
更新日期：2007-11-01 00:00:00
abstract：:Presentation of three cases of haemodialysis patients with acquired cystic renal disease (ACRD) who, over the course of their illness, developed clear cells renal carcinoma. The paper emphasizes the common association of these two entities and the need to consider ACRD cases as patients at high risk of developing rena...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:The paper reviews the various prophylaxis modalities in surface vesical tumours in order to define the degree of toxicity caused by each of them. Also, a prophylaxis diagram is prepared, having into account each substance's toxicity, the benefit awarded to each of then and the tumour prognosis. The agents under assess...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVES:To explore the management of lower urinary tract symptoms (LUTS) in men in Spain and assess the compliance with recommendations established in the European Association of Urology (EAU) guidelines. MATERIAL AND METHODS:MERCURY was an epidemiological and cross-sectional study which involved 227 Urology Units ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2017.12.003
更新日期：2018-06-01 00:00:00
abstract：:About 2% of adults have an urachal cyst. The diagnosis is usually made due to its clinical complications. We report an inusual case of acute urinary retention due to an urachal cyst, with hipogastric pain and anuria as initial syntoms. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73365-9
更新日期：2005-10-01 00:00:00
abstract：CONTEXT:Serum testosterone is mostly bound to the sex hormone-binding globulin and albumin. A small metabolically active part is present in the form of free testosterone (FT). The relationship between serum total testosterone (TT) levels and prostate carcinogenesis is debated. Our hypothesis is that the serum FT concen...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2015.03.004
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To know the presentation form, diagnostic method and clinical stage at the time of diagnosis in subjects with prostate cancer (PC) in the Autonomous Community of Madrid in 2000. MATERIAL AND METHOD:Data from 1745 patients with histologically confirmed prostate cancer obtained from 15 Hospitals participating ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/s0210-4806(03)72934-9
更新日期：2003-05-01 00:00:00
abstract：INTRODUCTION:In November of 1998, the Spanish Association of Urology decides to carry out a study on the lithotripsy in Spain, through the Group of Work in Lithiasis Urinary, with the objective of knowing the n(o) and distribution of Units and the real situation of the extracorporeal litotripsy for shock waves, in conn...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72531-9
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:To evaluate the diagnostic usefulness of the cytological study of the transport buffer in the diagnosis of prostate adenocarcinoma in transrectal core biopsies. METHODS:A total of 256 consecutively biopsied patients have been included in the analysis, 100 of them diagnosed of prostate adenocarcinoma. The pr...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.01.003
更新日期：2014-11-01 00:00:00
abstract：CONTEXT AND OBJECTIVES:The natural history of renal cell carcinoma is heterogeneous. Some scenarios can be found in terms of clinical presentation, clinical evolution or type of recurrence (local/metastatic). The aim of this publication is to analyze the most important prognostic factors published in the literature. E...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2016.08.003
更新日期：2017-05-01 00:00:00
abstract：:A prospective randomized study on 100 patients was conducted to determine the effect of the rectal digital examination on prostate specific antigen (PSA) serum concentration. The control group consisted of 50 patient, all with two PSA determinations with no urological manipulation between them. The study group had 50 ...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-01-01 00:00:00
abstract：:Vesical leiomyoma is a benign mesenchymal tumor that rarely involves the bladder and makes about 1.5% of all vesical tumors. A new case is presented and aspects concerning clinical, diagnostic and surgical issues are examined. The paper includes a revision of the available literature on the topic. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：PURPOSE:To compare the efficacy of ureteroscopy and extracorporeal shock wave lithotripsy (ESWL) in treating distal ureteral calculi and evaluate the best treatment alternative for this disease. MATERIAL AND METHODS:A total of 104 patients with distal ureteral calculi requiring surgical intervention were enrolled and ...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章
doi：10.1016/s0210-4806(09)72874-8
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:To analyze the indications, results and complications of embolisation of a non-tolerated, non-functioning renal graft with regards to surgical transplantectomy. MATERIAL AND METHODS:Between 1990 and 1998, 55 patients with failed renal graft were studied. Patients had undergone either subcapsular transplantec...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72455-7
更新日期：2000-04-01 00:00:00
