Above-knee amputation with insidious pulmonary embolism and hypercoagulability secondary to protein C deficiency.

Abstract:

:Pulmonary embolus can have insidious onset and unusual etiology. This case report of a 35-year-old woman with hyperthyroidism, atrial fibrillation, and an above-knee amputation demonstrates the subtle presentation of pulmonary emboli. On the rehabilitation ward of a tertiary care hospital, the patient developed undulating fever to 39.6C, rapidly worsening peripheral vascular disease, and pulmonary emboli. Eventually, a protein C deficiency was found; institution of appropriate therapy resulted in rapid improvement. This case reminds physiatrists to evaluate thoroughly the cause of pulmonary thrombi. Currently available assays permit rapid elucidation of factor deficiencies in the workup of the hypercoagulable state.

journal_name

Arch Phys Med Rehabil

authors

Sandin KJ,Smith BS

subject

Has Abstract

pub_date

1989-09-01 00:00:00

pages

699-701

issue

9

eissn

0003-9993

issn

1532-821X

pii

0003-9993(89)90170-6

journal_volume

70

pub_type

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