Cardiopulmonary exercise testing is well tolerated in people with Alzheimer-related cognitive impairment.

Abstract:

OBJECTIVE:To retrospectively assess whether cardiopulmonary exercise testing would be well tolerated in individuals with Alzheimer disease (AD) compared with a nondemented peer group. DESIGN:We retrospectively reviewed 575 cardiopulmonary exercise tests (CPETs) in individuals with and without cognitive impairment caused by AD. SETTING:University medical center. PARTICIPANTS:Exercise tests (N=575) were reviewed for nondemented individuals (n=340) and those with AD-related cognitive impairment (n=235). INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:The main outcome measure for this study was reporting the reason for CPET termination. The hypothesis reported was formulated after data collection. RESULTS:We found that in cognitively impaired individuals, CPETs were terminated because of fall risk more often, but that overall test termination was infrequent-5.5% versus 2.1% (P=.04) in peers without cognitive impairment. We recorded 6 cardiovascular and 7 fall risk events in those with AD, compared with 7 cardiovascular and 0 fall risk events in those without cognitive impairment. CONCLUSIONS:Our findings support using CPETs to assess peak oxygen consumption in older adults with cognitive impairment caused by AD.

journal_name

Arch Phys Med Rehabil

authors

Billinger SA,Vidoni ED,Greer CS,Graves RS,Mattlage AE,Burns JM

doi

10.1016/j.apmr.2014.04.007

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

1714-8

issue

9

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(14)00291-3

journal_volume

95

pub_type

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