Abstract:
OBJECTIVE:To examine if 8 weeks of high-intensity interval training (HIIT) in addition to standard care would increase and maintain peak oxygen uptake (Vo2peak) more than standard care alone in patients with stroke. DESIGN:This was a single-blind, multicenter, parallel group, randomized controlled trial. SETTING:Specialized rehabilitation units at 3 Norwegian hospitals. PARTICIPANTS:Participants (N=70), 3 months to 5 years after first-ever stroke, were randomly assigned to the intervention group (n=36) or the control group (n=34); 42% were women, mean age was 57.6±9.3 years, mean time post stroke was 26.4±14.5 months. INTERVENTION:The intervention was 8 weeks: 3 times a week with HIIT treadmill training with work periods of 4 × 4 minutes at 85%-95% of peak heart rate interspersed with 3 minutes of active recovery at 50%-70% of peak heart rate. The control group received standard care according to national guidelines. OUTCOMES:The primary outcome, analyzed by intention-to-treat, was Vo2peak measured as liters per minute 12 months after inclusion. Secondary outcome measures were blood pressure and blood profile. RESULTS:Mean baseline Vo2peak was 2.63±1.08 L·min-1 vs 2.87±0.71 L·min-1, while at 12 months Vo2peak was 2.70±1.00 L·min-1 vs 2.67±0.76 L·min-1 (P=.068) in the intervention and control groups, respectively. There was a significant and greater improvement in the intervention group compared with the control group at 12 months in 3 of 6 secondary outcomes from the peak test but no significant differences for blood pressure or blood profile. CONCLUSIONS:The HIIT intervention, which was well-tolerated in this sample of well-functioning survivors of stroke, was not superior to standard care in improving and maintaining Vo2peak at the 12-month follow-up. However, secondary results from the peak test showed a significant improvement from before to immediately after the intervention.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Gjellesvik TI,Becker F,Tjønna AE,Indredavik B,Nilsen H,Brurok B,Tørhaug T,Busuladzic M,Lydersen S,Askim Tdoi
10.1016/j.apmr.2020.02.006subject
Has Abstractpub_date
2020-06-01 00:00:00pages
939-947issue
6eissn
0003-9993issn
1532-821Xpii
S0003-9993(20)30141-6journal_volume
101pub_type
杂志文章,多中心研究,随机对照试验abstract::Musculoskeletal injuries can result from overuse or incorrect use of manual wheelchairs, and can hinder rehabilitation efforts. The purpose of this study was to investigate wheelchair propulsion biomechanics of spinal cord injured, non-athletic wheelchair users. We studied changes in the variables that occur with fati...
journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
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