Abstract：
:The absorption characteristics of drugs in spinal cord injury (SCI) were studied using an actively transported drug [riboflavin (RBF)] and a passively absorbed drug [acetaminophen (ACE)]. RBF absorption was studied following oral administration of 150mg RBF as 5'-phosphate flavin mononucleotide in ten clinically complete quadriplegic patients (C1 to C7, two to 15 months post-onset) and six control subjects matched for age, sex, and weight. Urinary excretion was measured under fasting (F) and nonfasting (NF) conditions for time to peak, peak excretion rate, and percent dose recovered. The results showed a significant difference (p less than 0.05) for all parameters between F and NF conditions for both the SCI and able-bodied groups. However, there was no significant difference for the same parameters between the two groups. ACE absorption was studied in five SCI clinically complete quadriplegic patients (C1 to C7, two to 15 months post-onset following the administration of a 650mg tablet. Serum samples were analyzed for ACE content and showed: time of peak, 1.35 +/- 0.6hr; maximum serum level, 6.8 +/- 2.68 micrograms/ml; half-life, 2.89 +/- 1.81hr; absorption lag time, 18.1 +/- 1.8min; area under the serum level-time curve, 21.8 +/- 6.7 micrograms/.hr/ml. When compared to able-bodied population data in the literature, there was a significant increase in the time to peak and lag time, and a decrease in the maximum ACE serum concentration obtained.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Halstead LS,Feldman S,Claus-Walker J,Patel VCsubject
Has Abstractpub_date
1985-05-01 00:00:00pages
298-301issue
5eissn
0003-9993issn
1532-821Xjournal_volume
66pub_type
杂志文章abstract：OBJECTIVE:To assess the relations between measures of activity with dyspnea and satisfaction with life in chronic spinal cord injury (SCI). DESIGN:Cross-sectional survey. SETTING:Five SCI centers. PARTICIPANTS:Between July 2012 and March 2015, subjects (N=347) with traumatic SCI ≥1 year after injury who used a manua...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2016.02.010
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To investigate whether changes over time are different in a weight-bearing leg muscle than in a less heavily used arm muscle. DESIGN:Prospective study. SETTING:University hospital laboratory. PARTICIPANTS:Twenty-three patients with a history of poliomyelitis. INTERVENTION:Two investigations were performed...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.08.101
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVE:This study was performed to compare the effects of a vapocoolant spray and a eutectic mixture of local anesthetics (EMLA) cream on reducing pain during intra-articular (IA) injection of the shoulder. DESIGN:Double-blind randomized placebo-controlled clinical trial. SETTING:University hospital. PARTICIPANTS...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2020.04.021
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To determine the feasibility and utility of applying a case-mix adjusted algorithm for treatment across the continuum of stroke rehabilitation. DESIGN:Implementation of a clinical algorithm developed through national expert panels to standardize rehabilitation assessment and treatment of veterans with stroke...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1053/apmr.2000.17808
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVES:To determine the characteristics and effectiveness of motor skill interventions in children with developmental coordination disorder (DCD) and to identify potential moderators of training effects using meta-analysis. DATA SOURCES:A search was conducted in 6 databases (CINAHL Plus, Cochrane Library, Embase, ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析
doi：10.1016/j.apmr.2017.12.009
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:To identify instruments that measure community participation in people with disabilities and to evaluate which domains, to what extent, and how precisely they address this construct. The review aims to provide information to guide the selection of community participation instruments and to identify limitation...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.apmr.2012.10.031
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:To describe the types, intensities, and average duration of leisure time physical activities (LTPAs) performed by people with chronic spinal cord injury (SCI). DESIGN:Cross-sectional telephone survey. SETTING:General community. PARTICIPANTS:Men and women with SCI (N=347) who reported engaging in LTPA over ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2009.12.028
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:To establish the feasibility and effectiveness of a 6-week ballistic strength training protocol in people with stroke. DESIGN:Randomized, controlled, assessor-blinded study. SETTING:Subacute inpatient rehabilitation. PARTICIPANTS:Consecutively admitted inpatients with a primary diagnosis of first-ever stro...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2018.04.032
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To determine whether regular performance of adapted sports is associated with long-term changes in carotid atherosclerosis in subjects with spinal cord injury (SCI). DESIGN:Prospective observational study. SETTING:Academic medical center. PARTICIPANTS:Men with chronic (>1y) SCI and no preserved motor funct...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2015.11.002
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVES:To determine if exercise-based rehabilitation reduces reinjury following acute ankle sprain. Our secondary objective was to assess if rehabilitation efficacy varies according to exercise content and training volume. DATA SOURCES:The following electronic databases were searched: EMBASE, MEDLINE, the Cochrane...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析
doi：10.1016/j.apmr.2018.10.005
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:To compare the renal excursion detected by ultrasonography with the diaphragmatic excursion recorded by fluoroscopy in estimating the diaphragmatic function in patients with high cervical cord injury. DESIGN:Prospective, blinded comparative study. SETTING:A rehabilitation hospital affiliated with a medical ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(03)00428-3
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:To establish whether there is evidence for or against the efficacy of needling as a treatment approach for myofascial trigger point pain. DATA SOURCES:PubMed, Ovid MEDLINE, Ovid EMBASE, the Cochrane Library, AMED, and CISCOM databases, searched from inception to July 999. STUDY SELECTION:Randomized, control...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1053/apmr.2001.24023
更新日期：2001-07-01 00:00:00
abstract：:The purpose of this investigation was to assess the relationship among selected physican and cardiorespiratory variables in active men, aged 40-59 years. Thirty-one subjects who had been running for only an average of five years volunteered for treadmill testing, running to volitional exhaustion. For the total group (...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1977-10-01 00:00:00
abstract：:Ninety-three men and women with histories of polio were administered the Symptom Check List-90 Revised (SCL-90R), Psychosocial Adjustment to Illness Scale-Self Report (PAIS-SR), and a questionnaire about their polio histories. The SCL-90R and PAIS-SR are measures of emotional and psychosocial functioning. Two samples ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(89)90007-5
更新日期：1989-06-01 00:00:00
abstract：OBJECTIVES:To identify risk and protective factors associated with a history of recurrent pressure ulcers among participants with spinal cord injury (SCI). DESIGN:A mail survey was used to identify factors associated with the presence or absence of recurrent pressure ulcers. SETTING:A large specialty hospital in the ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.08.108
更新日期：2004-08-01 00:00:00
abstract：:Traumatic brain injury (TBI) is often accompanied by additional trauma that can be obscured by cognitive dysfunction or multiple injuries in the same region of the body. This report describes the case of an unhelmeted motorcycle rider who collided with a telephone pole. He sustained a diffuse subarachnoid hemorrhage, ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1053/apmr.2001.26245
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVE:To investigate the reliability of isokinetic peak torque and work and isometric peak torque measurements for knee flexion and extension in fibromyalgia (FM) patients by determining the smallest real difference (SRD). DESIGN:Test-retest reliability study. SETTING:University laboratory. PARTICIPANTS:Women wi...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2011.04.017
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVES:To assess changes in peak functional aerobic power after a 36-session, progressive functional electric stimulation (FES) rowing hybrid training program for persons with spinal cord injury (SCI) and to examine the safety and acceptability of the ROWSTIM II device as well as the integrity of technical modifica...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1053/apmr.2002.33656
更新日期：2002-08-01 00:00:00
abstract：OBJECTIVE:To compare the effects of 2 different heat modalities, infrared and ultrasonic therapy, on a knee flexion contracture. DESIGN:In vivo, experimental, controlled study involving a rat knee joint contracture model that was immobilized using a ligature in flexion for 40 days. SETTING:Collegiate research laborat...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2005.10.015
更新日期：2006-02-01 00:00:00
abstract：:Straight-leg raising is used as a diagnostic test for both elastogenic (passive muscle stretch test) and nonelastogenic (Lasègue's test) pathology in patients unable to bend forward from the standing position while holding the knees in extension. The test assessment is based on the range of the leg excursion and the t...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1016/0003-9993(94)90174-0
更新日期：1994-04-01 00:00:00
abstract：OBJECTIVE:To examine interrater agreement of scores by physical therapy novices and experienced clinicians on videotaped and live performances of the balance portion of Tinetti's Performance Oriented Mobility Assessment (BPOMA). DESIGN:A reliability design was used to assess the interrater agreement and consistency of...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(97)90145-3
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVES:To establish self-efficacy and depressive mood trajectories in adults with spinal cord injury (SCI), determine their interrelationship over time, and determine the influence that appraisals and comorbid physical conditions have on the development of self-efficacy. DESIGN:A prospective cohort design. SETTIN...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.07.442
更新日期：2019-03-01 00:00:00
abstract：:To study the relationship between isokinetic and isometric torque, maximum voluntary contractions were elicited from 352 male volunteers. Knee extensors, knee flexors, elbow extensors, and elbow flexors were tested isometrically and at isokinetic velocities of 30 degrees/sec, 90 degrees/sec, and 180 degrees/sec on a m...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：OBJECTIVE:To compare functional outcomes between children receiving inpatient rehabilitation at children's hospitals and those at other facilities. DESIGN:Retrospective cohort study. SETTING:Inpatient rehabilitation facilities. PARTICIPANTS:Children (N=28,793) aged 6 months to 18 years who received initial inpatient...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.apmr.2016.02.026
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:To summarize adverse events reported in randomized controlled trials that applied progressive resistance strength training in older adults and to examine factors that might be associated with these events. DESIGN:After systematic searches of databases, 2 reviewers independently screened and extracted advers...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.apmr.2010.06.001
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:To describe the etiology, clinical presentation, complications, outcome indicators, and links between emergency and acute intervention and rehabilitation of patients with traumatic spinal cord injury (SCI). DESIGN:Multicenter prospective study involving patients with SCI discharged, after rehabilitative care...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1016/s0003-9993(03)00234-x
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To determine if there were racial differences in discharge location among older adults treated for traumatic brain injury (TBI) at a level 1 trauma center. DESIGN:Retrospective cohort study. SETTING:R Adams Cowley Shock Trauma Center. PARTICIPANTS:Black and white adults aged ≥65 years treated for TBI betwe...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2019.03.008
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To identify implementation priorities for poststroke aphasia management relevant to the Australian health care context. DATA SOURCES:Using systematized searches of databases (CINAHL and MEDLINE), guideline and stroke websites, and other sources, evidence was identified and extracted for 7 implementation crit...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2017.08.474
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the reliability and validity of clinical tests for measuring cervical muscle strength or endurance in participants with and without neck pain. DATA SOURCE:Systematic review and meta-analysis on reliability and validity. Literature search was conducted on January 28, 2020, using 5 databases: MEDLI...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.apmr.2020.11.018
更新日期：2020-12-28 00:00:00
abstract：:Of the several roads that lead to practice in the specialty of physical medicine and rehabilitation (PM&R), the most common is from a US medical school to a PM&R residency to specialty practice. To reduce the predicted shortage of PM&R physicians, more medical students must be attracted to the specialty. Past studies ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
