Post-traumatic changes in, and effect of colloid osmotic pressure on the distribution of body water.

Abstract:

:The aim of this study was to define the post-traumatic changes in body fluid compartments and to evaluate the effect of plasma colloid osmotic pressure (COP) on the partitioning of body fluid between these compartments. Forty-two measurements of plasma volume (green dye), extracellular volume (bromine), and total body water (deuterium) were done in ten traumatized patients (mean Injury Severity Score, ISS, = 34) and 23 similar control studies were done in eight healthy volunteers who were in stable fluid balance. Interstitial volume, intracellular volume, and blood volume were calculated from measured fluid spaces and hematocrit; COP was directly measured. Studies in volunteers on consecutive days indicated good reproducibility, with coefficients of variation equal to 3.5% for COP, 6.3% for plasma volume, 4.5% for extracellular volume, and 4.9% for total body water. COP values extended over the entire range seen clinically, from 10 to 30 mmHg. Interstitial volume was increased by 55% in patients, but intracellular volume was decreased by 10%. We conclude (1) that posttraumatic peripheral edema resulting from hemodilution is located in the interstitial compartment, with no intracellular space expansion; and (2) that interstitial volume, but not intracellular volume, is closely related to plasma COP.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Böck JC,Barker BC,Clinton AG,Wilson MB,Lewis FR

doi

10.1097/00000658-198909000-00015

subject

Has Abstract

pub_date

1989-09-01 00:00:00

pages

395-403; discussion 403-5

issue

3

eissn

0003-4932

issn

1528-1140

journal_volume

210

pub_type

杂志文章
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    doi:10.1097/00000658-198101000-00009

    authors: Glenn F

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    authors: Gaur P,Leary C,Yao JC

    更新日期:2010-06-01 00:00:00

  • Carcinoid syndrome from gastrointestinal carcinoids without liver metastasis.

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    authors: Feldman JM,Jones RS

    更新日期:1982-07-01 00:00:00

  • The impact of Clostridium difficile on a surgical service: a prospective study of 374 patients.

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    pub_type: 杂志文章

    doi:10.1097/00000658-199802000-00021

    authors: Kent KC,Rubin MS,Wroblewski L,Hanff PA,Silen W

    更新日期:1998-02-01 00:00:00

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    doi:10.1097/00000658-198302000-00003

    authors: Tibblin S,Pålsson N,Rydberg J

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  • Invasive intraductal papillary mucinous carcinomas of the pancreas: predictors of survival and the role of lymph node ratio.

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    journal_title:Annals of surgery

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    doi:10.1097/SLA.0b013e3181cf9155

    authors: Partelli S,Fernandez-Del Castillo C,Bassi C,Mantovani W,Thayer SP,Crippa S,Ferrone CR,Falconi M,Pederzoli P,Warshaw AL,Salvia R

    更新日期:2010-03-01 00:00:00

  • Protein-sparing effect in skeletal muscle of growth hormone treatment in critically ill patients.

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    authors: Gamrin L,Essén P,Hultman E,McNurlan MA,Garlick PJ,Wernerman J

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    pub_type: 杂志文章

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    authors: Loop FD,Cosgrove DM,Lytle BW,Thurer RL,Simpfendorfer C,Taylor PC,Proudfit WL

    更新日期:1979-10-01 00:00:00

  • Metabolic and hormonal studies comparing three parenteral nutrition regimens in infants.

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    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

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    authors: Asch MJ,Sperling M,Fiser R,Leake R,Moore TC,Oh W

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  • Implementation of an Effective Strategy for Teaching Nontechnical Skills in the Operating Room: A Single-blinded Nonrandomized Trial.

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  • Chemotherapy or liver transplantation for nonresectable liver metastases from colorectal cancer?

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    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

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    doi:

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  • Multicenter Stratified Comparison of Hospital Costs Between Laparoscopic and Open Colorectal Cancer Resections: Influence of Tumor Location and Operative Risk.

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  • Lead poisoning from retained missiles. An experimental study.

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    pub_type: 杂志文章

    doi:10.1097/00000658-198611000-00014

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