The comparative influence of prophylactic antibiotics on the prothrombin response to warfarin in the postoperative prosthetic cardiac valve patient. Cefamandole, cefazolin, vancomycin.

Abstract:

:A prospective randomized trial was conducted comparing the effect of three antibiotics: cefamandole (CM), cefazolin (CZ), and vancomycin (V), used as prophylaxis for prosthetic valve surgery, on the prothrombin (PT) response to warfarin (W) on the third day of anticoagulant therapy. Twenty patients, with normal preoperative PTs, were randomized to each antibiotic. Their PTs were not significantly different at 2 hours after operation and the morning before W was begun. The three groups received similar W doses for 2 days, and the PT, as percentage of activity, on the morning of the third day demonstrated that V (51 +/- 18%) was significantly greater (p less than 0.005) than CM (29 +/- 14%) or CZ (38 +/- 18%). CM had a significantly greater percentage of change in PT (64 +/- 14%, p less than 0.0001) from the first to third day than either CZ (51.1 +/- 18%) or V (44.6 +/- 19%). CM also had a greater number of patients (6) with PTs greater than or equal to 30 seconds on day 3 than either CZ (1) or V (1). The antibiotic influence on the PT response to W in this study is ranked as CM greater than CZ greater than V.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Angaran DM,Dias VC,Arom KV,Northrup WF,Kersten TG,Lindsay WG,Nicoloff DM

doi

10.1097/00000658-198708000-00007

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

155-61

issue

2

eissn

0003-4932

issn

1528-1140

journal_volume

206

pub_type

临床试验,杂志文章,随机对照试验
  • Renal blood flow and intrarenal distribution of blood flow after decapsulation in the postischemic kidney.

    abstract::Previous reports suggest the value of renal decapsulation in the prevention of renal failure after acute ischemia. It has been suggested that this response is due to a release of "compartmental" pressure resulting in increased blood flow to the decapsulated kidney. Ten dogs were evaluated following 90 minutes of renal...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198004000-00011

    authors: Stothert JC Jr

    更新日期:1980-04-01 00:00:00

  • Brochial stump closure techniques following pneumonectomy: A serial comparative study.

    abstract::Three methods of closing bronchial stumps were evaluated in 90 dogs undergoing left pneumonectomy:interrupted 3-0 silk sutures, interrupted 3-0 nylon sutures, and stapling with an automatic device. The dogs were sacrificed at 24 hours, 3, 5, 7, 10, and 14 days after pneumonectomy. Brochial stump leakage pressures and ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197608000-00012

    authors: Scott RN,Faraci RP,Hough A,Chretien PB

    更新日期:1976-08-01 00:00:00

  • Computed tomography in the diagnosis of intra-abdominal abscesses.

    abstract::The diagnosis of intra-abdominal abscess by radiographic means often relies on combining the results of several different imaging modalities. Computed tomography (CT) has been shown to be a safe, accurate and rapid diagnostic method of diagnosing these abscesses. Five patients with a variety of intra-abdominal abscess...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197901000-00006

    authors: Daffner RH,Halber MD,Morgan CL,Trought WS,Thompson WM,Rice RP

    更新日期:1979-01-01 00:00:00

  • Carotid endarterectomy in the community hospital in patients age 80 and older.

    abstract:OBJECTIVE:To determine whether the rates of death and complications of carotid endarterectomy (CE) were different in the octogenarian population than in patients younger than age 80. SUMMARY BACKGROUND DATA:The utility of CE depends on the ability of the surgeon and hospital to attain low rates of death and complicati...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200006000-00001

    authors: Maxwell JG,Taylor AJ,Maxwell BG,Brinker CC,Covington DL,Tinsley E Jr

    更新日期:2000-06-01 00:00:00

  • The Global Incidence of Appendicitis: A Systematic Review of Population-based Studies.

    abstract:OBJECTIVE:We compared the incidence of appendicitis or appendectomy across the world and evaluated temporal trends. SUMMARY BACKGROUND DATA:Population-based studies reported the incidence of appendicitis. METHODS:We searched MEDLINE and EMBASE databases for population-based studies reporting the incidence of appendic...

    journal_title:Annals of surgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/SLA.0000000000002188

    authors: Ferris M,Quan S,Kaplan BS,Molodecky N,Ball CG,Chernoff GW,Bhala N,Ghosh S,Dixon E,Ng S,Kaplan GG

    更新日期:2017-08-01 00:00:00

  • Early postoperative small bowel obstruction.

    abstract::The hospital records of 41 patients with a diagnosis of early postoperative small bowel obstruction were reviewed in an attempt to identify criteria which could be used to separate those patients who would require an operation to resolve their obstruction, from those who would resolve with nonoperative therapy. The us...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198001000-00014

    authors: Quatromoni JC,Rosoff L Sr,Halls JM,Yellin AE

    更新日期:1980-01-01 00:00:00

  • Complications of vagotomy in the treatment of hiatal hernia.

    abstract::Inclusion of vagotomy and pyloroplasty in the surgical treatment of gastroesophageal reflux associated with hiatal hernia has long been controversial. To evaluate the morbidity of vagotomy in the treatment of reflux esophagitis, a retrospective study of 311 patients treated by the Hill posterior gastropexy technique o...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197606000-00003

    authors: Vansant JH,Baker JW Jr

    更新日期:1976-06-01 00:00:00

  • Management of Five Hundred Patients With Gut Failure at a Single Center: Surgical Innovation Versus Transplantation With a Novel Predictive Model.

    abstract:OBJECTIVE(S):To define the evolving role of integrative surgical management including transplantation for patients gut failure (GF). METHODS:A total of 500 patients with total parenteral nutrition-dependent catastrophic and chronic GF were referred for surgical intervention particularly transplantation and comprised t...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003523

    authors: Abu-Elmagd KM,Armanyous SR,Fujiki M,Parekh NR,Osman M,Scalish M,Newhouse E,Fouda Y,Lennon E,Shatnawei A,Kirby D,Steiger E,Khanna A,Radhakrishnan K,Quintini C,Hashimoto K,Barnes J,Costa G

    更新日期:2019-10-01 00:00:00

  • Soft tissue sarcomas.

    abstract::One hundred fifty-five adult patients with "operable" soft part sarcomas including rhabdomyosarcoma, liposarcoma, leiomyosarcoma and fibrosarcoma of the trunk and extremities are reviewed. Local recurrences of 93% and 60% occurred after local and wide excisions of the primary tumor. In this series of patients, amputat...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197506000-00007

    authors: Gerner RE,Moore GE,Pickren JW

    更新日期:1975-06-01 00:00:00

  • Endocrine Surgery: A Hopkins Legacy.

    abstract::: The field of Endocrine Surgery is linked to extraordinary contributions made by Hopkins leaders in surgery including William Stewart Halsted, Harvey Cushing, and John L Cameron. Halsted's contributions to the anatomic basis of thyroid and parathyroid surgery were based on his experimental and clinical work performed...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002519

    authors: Udelsman R

    更新日期:2018-02-01 00:00:00

  • The Australian and New Zealand Audit of Surgical Mortality-birth, deaths, and carriage.

    abstract:OBJECTIVE:This article outlines the formation of the Australian and New Zealand Audit of Surgical Mortality (ANZASM) and describes its objectives, governance, functioning and challenges. BACKGROUND:A nationwide audit of surgical mortality provides an overview of the leading causes of death in patients who require surg...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000000581

    authors: Raju RS,Guy GS,Majid AJ,Babidge W,Maddern GJ

    更新日期:2015-02-01 00:00:00

  • Intestinal Oxygenation and Survival After Surgery for Necrotizing Enterocolitis: An Observational Cohort Study.

    abstract:OBJECTIVE:To assess whether regional intestinal oxygen saturation (rintSO2) and regional cerebral oxygen saturation (rcSO2) measurements aid in estimating survival of preterm infants after surgery for NEC. SUMMARY OF BACKGROUND DATA:Predicting survival after surgery for NEC is difficult yet of the utmost importance fo...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003913

    authors: Kuik SJ,van der Heide M,Bruggink JLM,Bos AF,Verhagen AAE,Kooi EMW,Hulscher JBF

    更新日期:2020-04-20 00:00:00

  • Pigment gallstones form as a composite of bacterial microcolonies and pigment solids.

    abstract::Although previous studies have suggested that bacteria may contribute to pigment gallstone formation, the current experiments provide evidence that bacteria have a central role in this process. The studies included scanning electron microscopy (SEM) of gallstones, measurements of bacterial adherence to gallstones in v...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198709000-00002

    authors: Stewart L,Smith AL,Pellegrini CA,Motson RW,Way LW

    更新日期:1987-09-01 00:00:00

  • End-to-end versus end-to-side esophagogastrostomy after esophageal cancer resection: a prospective randomized study.

    abstract:OBJECTIVE:To compare single-layered hand-sewn cervical end-to-side (ETS) anastomosis with end-to-end (ETE) anastomosis in a prospective randomized fashion. BACKGROUND:The preferred organ used for reconstruction after esophagectomy for cancer is the stomach. Previous studies attempted to define the optimal site of anas...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0b013e31822676a9

    authors: Nederlof N,Tilanus HW,Tran TC,Hop WC,Wijnhoven BP,de Jonge J

    更新日期:2011-08-01 00:00:00

  • Use of abdominal ultrasonography to assess pediatric splenic trauma. Potential pitfalls in the diagnosis.

    abstract:OBJECTIVE:The purpose of this study was to evaluate the accuracy of abdominal ultrasonography (US) for screening and grading pediatric splenic injury. SUMMARY BACKGROUND DATA:The use of abdominal US has increased rapidly as a method of evaluating organ damage after blunt abdominal trauma. Despite US's increasing use, ...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000658-199704000-00010

    authors: Krupnick AS,Teitelbaum DH,Geiger JD,Strouse PJ,Cox CS,Blane CE,Polley TZ

    更新日期:1997-04-01 00:00:00

  • Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma.

    abstract:OBJECTIVE:To evaluate the current knowledge on the risk factors for recurrence, efficacy of adjuvant therapy in preventing recurrence, and the optimal management of recurrence after resection of hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA:The long-term prognosis after resection of HCC remains unsatisfactor...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000658-200007000-00003

    authors: Tung-Ping Poon R,Fan ST,Wong J

    更新日期:2000-07-01 00:00:00

  • Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus.

    abstract::The postoperative function of "free" jejunal autotransplants for replacement of the pharyngoesophagus after palliative resection was evaluated in nine patients using clinical assessment, cinefluoroscopy, manometry, and electrical studies. After an initial period of adjustment, all patients swallowed solids and liquids...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198010000-00002

    authors: Meyers WC,Seigler HF,Hanks JB,Thompson WM,Postlethwait R,Jones RS,Akwari OK,Cole TB

    更新日期:1980-01-01 00:00:00

  • Fetal allograft survival in immunocompetent recipients is age dependent and organ specific.

    abstract::This study explores whether fetal allograft survival is age dependent and organ specific. Fetal rat tissue (renal, gonadal, hepatic) from the third trimester of gestation (days 15-21) was transplanted into 306 outbred adult rats for 10-30 days. Grafts were studied by morphometric and histologic analysis. Ten days afte...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198610000-00008

    authors: Foglia RP,DiPreta J,Statter MB,Donahoe PK

    更新日期:1986-10-01 00:00:00

  • Outcomes of Posterior Component Separation With Transversus Abdominis Muscle Release and Synthetic Mesh Sublay Reinforcement.

    abstract:OBJECTIVE:To evaluate the safety and efficacy of transversus abdominis muscle release (TAR) with retrorectus synthetic mesh reinforcement in a large series of complex hernia patients. BACKGROUND:Posterior component separation via TAR during abdominal wall reconstruction (AWR) continues to gain popularity. Although our...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001673

    authors: Novitsky YW,Fayezizadeh M,Majumder A,Neupane R,Elliott HL,Orenstein SB

    更新日期:2016-08-01 00:00:00

  • What Promotes Surgeon Practice Change? A Scoping Review of Innovation Adoption in Surgical Practice.

    abstract:OBJECTIVE:The goal of this scoping review was to summarize the literature on facilitators and barriers to surgical practice change. This information can inform research to implement best practices and evaluate new surgical innovations. BACKGROUND:In an era of accelerated innovations, surgeons face the difficult decisi...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004355

    authors: Arroyo NA,Gessert T,Hitchcock M,Tao M,Smith CD,Greenberg C,Fernandes-Taylor S,Francis DO

    更新日期:2020-08-26 00:00:00

  • Predictive index for long-term survival after retransplantation of the liver in adult recipients: analysis of a 26-year experience in a single center.

    abstract:OBJECTIVE:To develop a prognostic scoring system for risk stratification of patients with hepatic graft failure (GF) undergoing retransplants of the liver (ReLT) and improve patient selection. SUMMARY OF BACKGROUND DATA:Retransplantation of the liver remains controversial because of inferior outcomes compared with the...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31822c5878

    authors: Hong JC,Kaldas FM,Kositamongkol P,Petrowsky H,Farmer DG,Markovic D,Hiatt JR,Busuttil RW

    更新日期:2011-09-01 00:00:00

  • Surgical management of carcinoma of the junction of the main hepatic ducts.

    abstract::Twenty-six patients are reviewed who had primary carcinomas involving the junction of the hepatic ducts. The majority had had an initial procedure of palliative biliary diversion elsewhere and were referred for further treatment. In three cases, en bloc resection of the tumor with total hepatectomy and orthotopic live...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197607000-00012

    authors: Fortner JG,Kallum BO,Kim DK

    更新日期:1976-07-01 00:00:00

  • New technique for liver resection using heat coagulative necrosis.

    abstract:OBJECTIVE:To assess a new bloodless technique using radiofrequency energy for segmental liver resection of hepatic tumors. SUMMARY BACKGROUND DATA:Liver resection remains a formidable surgical procedure; safe performance requires a high level of training and skill. Intraoperative blood loss during liver resection rema...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200211000-00004

    authors: Weber JC,Navarra G,Jiao LR,Nicholls JP,Jensen SL,Habib NA

    更新日期:2002-11-01 00:00:00

  • Evaluation of hepatic venous congestion: proposed indication criteria for hepatic vein reconstruction.

    abstract:OBJECTIVE:To establish criteria for venous reconstruction of middle hepatic vein (MHV) tributaries of the right liver graft in adult-to-adult living donor liver transplantation (LDLT). SUMMARY BACKGROUND DATA:In adult LDLT using the right hemiliver, the MHV is usually separated from the graft, which results in potenti...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000658-200208000-00013

    authors: Sano K,Makuuchi M,Miki K,Maema A,Sugawara Y,Imamura H,Matsunami H,Takayama T

    更新日期:2002-08-01 00:00:00

  • Enteral contrast in the computed tomography diagnosis of appendicitis: comparative effectiveness in a prospective surgical cohort.

    abstract:OBJECTIVE:Our goal was to perform a comparative effectiveness study of intravenous (IV)-only versus IV + enteral contrast in computed tomographic (CT) scans performed for patients undergoing appendectomy across a diverse group of hospitals. BACKGROUND:Small randomized trials from tertiary centers suggest that enteral ...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000000272

    authors: Drake FT,Alfonso R,Bhargava P,Cuevas C,Dighe MK,Florence MG,Johnson MG,Jurkovich GJ,Steele SR,Symons RG,Thirlby RC,Flum DR,Writing Group for SCOAP-CERTAIN.

    更新日期:2014-08-01 00:00:00

  • Editorial (Spring) Board? Gender Composition in High-impact General Surgery Journals Over 20 Years.

    abstract:OBJECTIVE:To quantify gender composition of 10 high-impact general surgery journals, delineate how board composition has changed over time, and evaluate qualification metrics by gender. BACKGROUND:Underrepresentation of women on editorial boards may contribute to the gender-based achievement gap in surgery. METHODS:W...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002667

    authors: Harris CA,Banerjee T,Cramer M,Manz S,Ward ST,Dimick J,Telem DA

    更新日期:2019-03-01 00:00:00

  • Nationwide Procedural Trends for Renal Trauma Management.

    abstract:OBJECTIVE:To characterize national trends in procedural management of renal trauma. BACKGROUND:Management of renal trauma has evolved to favor a more conservative approach. For patients requiring intervention, there is a paucity of information to characterize the nature of procedural therapy administered. METHODS:A r...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002475

    authors: Colaco M,Navarrete RA,MacDonald SM,Stitzel JD,Terlecki RP

    更新日期:2019-02-01 00:00:00

  • Detrimental effects of removing end-expiratory pressure prior to endotracheal extubation.

    abstract::Patients recovering from acute respiratory insufficiency are usually not extubated until they can ventilate adequately while breathing spontaneously at ambient end-expiratory pressure (T-tube). It is hypothesized that this period of T-tube breathing might be detrimental to gas exchange since the endotracheal tube abol...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198005000-00004

    authors: Annest SJ,Gottlieb M,Paloski WH,Stratton H,Newell JC,Dutton R,Powers SR Jr

    更新日期:1980-05-01 00:00:00

  • Specialty networking in pediatric surgery: a paradigm for the future of academic surgery.

    abstract:OBJECTIVE:To review retrospectively a 4-year experience with pediatric surgical networking at a major academic medical center in the Midwest. BACKGROUND:The growth of managed care in the United States during the past decade has had a major impact on the practice of medicine in general, but especially on academic medic...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199909000-00006

    authors: Coran AG,Blackman PM,Sikina C,Harmon CM,Lelli JL Jr,Geiger JD,Hirschl RB,Teitelbaum DH,Polley TZ Jr,Golladay ES,Austin E,Adelman SH

    更新日期:1999-09-01 00:00:00

  • Prevalence, Management and Outcomes Related to Preoperative Medical Orders for life Sustaining Treatment (MOLST) in an Adult Surgical Population.

    abstract:OBJECTIVE:To determine prevalence of documented preoperative code status discussions and post-operative outcomes (specifically mortality, readmission and discharge disposition) of patients with completed Medical Orders for Life-Sustaining Treatments (MOLST) forms before surgery. SUMMARY OF BACKGROUND DATA:A MOLST form...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004675

    authors: Tanious M,Lindvall C,Cooper Z,Tukan N,Peters S,Streid J,Fields K,Bader A

    更新日期:2020-12-18 00:00:00