Multiple cutaneous malignant melanomas with features of primary melanoma.

Abstract:

:A case report and review of the literature regarding multiple primary melanomas, and a discussion of the histologic differentiation between cutaneous primary melanomas and dermal metastases are presented. This report concerns a patient who, following wide surgical resection of a 1.3 mm thick primary melanoma with satellite lesions, developed eight additional primary lesions and more than 50 dermal metastases. The primary nature of the lesions was confirmed by detailed pathologic study. The patient was rendered free of disease over a two-year period of intralesional injection of Bacillus Calmette-Guerin (BCG) and purified tuberculin protein. This was accompanied by substantial improvement in immune function tests. Although this patient represents an uncommon clinical entity, treatment results suggest that aggressive intralesional immunotherapy may complement surgical resection in achieving successful palliation of patients with multiple primary melanomas.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Unger SW,Wanebo HJ,Cooper PH

doi

10.1097/00000658-198102000-00021

subject

Has Abstract

pub_date

1981-02-01 00:00:00

pages

245-50

issue

2

eissn

0003-4932

issn

1528-1140

journal_volume

193

pub_type

杂志文章
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    authors: Rogers DA,Elstein AS,Bordage G

    更新日期:2001-02-01 00:00:00

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    更新日期:2016-12-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1097/00000658-197410000-00025

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    doi:10.1097/00000658-198506000-00014

    authors: Edwards WH,Edwards WH Jr,Mulherin JL Jr,Jenkins JM

    更新日期:1985-06-01 00:00:00

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    doi:10.1097/00000658-199405000-00007

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  • Aneurysm of the aorta treated by wiring: case report of a 38-year survival.

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    pub_type: 杂志文章

    doi:10.1097/00000658-197612000-00014

    authors: Altman P,Voorhees AB Jr

    更新日期:1976-12-01 00:00:00

  • Regional intestinal blood flow and nitric oxide synthase inhibition during sepsis in the rat.

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    doi:10.1097/00000658-199801000-00018

    authors: Klemm K,Moody FG

    更新日期:1998-01-01 00:00:00

  • The core competencies of James Marion Sims, MD.

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    pub_type: 传,历史文章,杂志文章

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  • Villous tumors of the duodenum.

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  • Resection for pancreatitis in patients with pancreas divisum.

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  • Thrombotic thrombocytopenic purpura (TTP) and splenectomy: a current appraisal.

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    pub_type: 杂志文章

    doi:10.1097/00000658-197811000-00021

    authors: Rutkow IM

    更新日期:1978-11-01 00:00:00

  • "Sideways": results of repair of biliary injuries using a policy of side-to-side hepatico-jejunostomy.

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    pub_type: 杂志文章,评审

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    doi:10.1097/01.sla.0000154259.73060.f1

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