The Influence of High-Altitude Acclimatization on Ventilatory and Blood Oxygen Saturation Responses During Normoxic and Hypoxic Testing.

Abstract:

:We investigated how acclimatization effects achieved during a high-altitude alpinist expedition influence endurance performance, ventilation ([Formula: see text]) and blood oxygen saturation (SaO2) in normoxic (NOR) and hypoxic conditions (HYP). An incremental testing protocol on a cycle ergometer was used to determine the power output corresponding to the Lactate (PLT) and Ventilatory Threshold (PVT) in NOR and HYP (FiO2=0.13) as indirect characteristics of endurance performance in both conditions. Furthermore, changes in [Formula: see text], SaO2, blood pH and Pco2 were measured at a similar absolute exercise intensity of 180 W in NOR and HYP conditions. Seven experienced alpinists (mean ± SD: age: 50 ± 6 yrs; body mass: 76 ± 5 kg; body height: 175 ± 8 cm) volunteered to participate in this study after they had reached the summit of Gasherbrum II and Ama Dablam. They had therefore experienced the limitations of their acclimatization. Individual differences of PLT between values reached after and before the expedition (∆PLT) correlated (r = 0.98, p = 0.01) with differences of SaO2 (∆SaO2) in HYP, and differences of PVT (∆PVT) correlated (r = -0.83, p = 0.02) with differences of [Formula: see text] in HYP. The results suggest that the acclimatization may not have an equivocal and simple influence on the performance in hypoxia: enhanced blood oxygen saturation may be accompanied by increased endurance only, when the increase exceeded 2-3%, but enhanced ventilation, when increased more than 10 l/min in HYP, could detrimentally influence endurance.

journal_name

J Hum Kinet

authors

Ušaj A,Burnik S

doi

10.1515/hukin-2015-0149

subject

Has Abstract

pub_date

2016-04-13 00:00:00

pages

125-133

eissn

1640-5544

issn

1899-7562

pii

hukin-2015-0149

journal_volume

50

pub_type

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