Sentinel Lymph Node Detection by Blue Dye Versus Indocyanine Green Fluorescence Imaging in Colon Cancer.

abstract：:The high glucose consumption of tumour cells has been well known since Warburg's investigations. Nevertheless, the reason for this phenomenon is still a matter of speculation. Glucose uptake of tumour cells is mainly mediated by GLUT1. In this study, the question of whether glucose uptake as well as expression of GLUT...

journal_title：Anticancer research

authors： Hauptmann S,Grünewald V,Molls D,Schmitt WD,Köbel M,Kriese K,Schürmann A

更新日期：2005-09-01 00:00:00

abstract：:We studied 19 patients, 12 males and 7 females of a median age of 49 years (range 26-76) with clinical manifestations of gastro-intestinal (GI) involvement from malignant melanoma. Their records were available from an electronic database of 2163 patients registered between 1977 and 1998 with the Melanoma Unit initiall...

journal_title：Anticancer research

authors： Retsas S,Christofyllakis C

更新日期：2001-03-01 00:00:00

abstract：:The aim of this project was to study the kinetics of both Tl and Tc-99m MIBI in PBM by evaluating tumor to normal tissue ratio in early (E) images acquired within 1/2 hour and delayed (D) images acquired three hours following the i.v. injection of 3 mCi (111 MBq) of Tl and 20 mCi (740 MBq) of MIBI on 2 separate days i...

journal_title：Anticancer research

authors： Omar WS,Eissa S,Moustafa H,Farag H,Ezzat I,Abdel-Dayem HM

更新日期：1997-05-01 00:00:00

abstract：AIM:We aimed to retrospectively investigate the outcomes and pathological effects of retrograde superselective intra-arterial chemoradiotherapy (IACRT) combined with hyperthermia on metastatic lymph nodes of patients with oral squamous cell carcinoma. PATIENTS AND METHODS:Patients with lymph node metastasis from oral ...

journal_title：Anticancer research

authors： Nozato T,Koizumi T,Hayashi Y,Iida M,Iwai T,Oguri S,Hirota M,Kioi M,Koike I,Hata M,Tohnai I,Mitsudo K

更新日期：2019-03-01 00:00:00

abstract：:Malignant gliomas are often treated with cisplatin (cis-diamminedichloroplatinum(II), CDDP) and radiation but results remain unsatisfactory. To investigate whether CDDP induces radioresistance in glioma, T98G human glioblastoma cells were pretreated 5 times with 10(-6)M CDDP for 24 hours and then the sensitivity of wi...

journal_title：Anticancer research

authors： Poppenborg H,Münstermann G,Knüpfer MM,Hotfilder M,Hacker-Klom U,Wolff JE

更新日期：1997-03-01 00:00:00

abstract：:We generated a recombinant immunotoxin, named scFv(MGR6)-Cla, composed of the Fv region of an anti ErbB2 monoclonal antibody (MGR6) fused to clavin, a type 1 ribosome-inactivating protein (RIP) from Aspergillus clavatus. ErbB2 is a tyrosine kinase receptor which is overexpressed in most adenocarcinomas; clavin is a 17...

journal_title：Anticancer research

authors： D'Alatri L,Di Massimo AM,Anastasi AM,Pacilli A,Novelli S,Saccinto MP,De Santis R,Mele A,Parente D

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:In this study, the effect of novel taxane SB-T-1216 and paclitaxel on sensitive MDA-MB-435 and resistant NCI/ADR-RES human breast cancer cells was compared. MATERIALS AND METHODS:Cell growth and survival were evaluated after 96-hour incubation with tested concentrations of taxanes. The effect on the formati...

journal_title：Anticancer research

authors： Kovár J,Ehrlichová M,Smejkalová B,Zanardi I,Ojima I,Gut I

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND/AIM:Since antigenic peptides of the cancer-associated antigens presented on human leukocyte antigen (HLA) molecules are recognized by specific cytotoxic T-lymphocytes, they have the potential to becoming effective peptide vaccines for cancer immunotherapy. MATERIALS AND METHODS:Peptides binding to HLA-A*020...

journal_title：Anticancer research

authors： Kamata Y,Kuhara A,Iwamoto T,Hayashi K,Koido S,Kimura T,Egawa S,Homma S

更新日期：2013-05-01 00:00:00

abstract：:The usefulness of lymphocyte subset change as an indicator for predicting survival time and the effectiveness of combined treatment with an immunopotentiator, lentinan, and carboplatin (CBDCA) were investigated. Of 13 patients with advanced unresectable cancer entered in this study, 9 were administered 2 mg/body lenti...

journal_title：Anticancer research

authors： Matsuoka H,Yano K,Seo Y,Saito T,Tomoda H,Tsurumoto S

更新日期：1995-09-01 00:00:00

abstract：:Amitriptyline, a tricyclic antidepressant, was able to reverse the multidrug resistance efflux pump of human colon cancer subline SW 620 and multidrug resistant (mdr) mouse lymphoma cells by decreasing rhodamine 123 efflux. The inhibitory effect of amitriptyline on the efflux pump was dose dependent. An investigation ...

journal_title：Anticancer research

authors： Varga A,Nugel H,Baehr R,Marx U,Hevér A,Nacsa J,Ocsovszky I,Molnar J

更新日期：1996-01-01 00:00:00

abstract：:The aims of this study were to evaluate the pharmacokinetics, tolerability and hematopoietic toxicity of mitoxantrone in elderly women. Thirteen patients with advanced breast cancer, median age of 73 years, received escalating doses of mitoxantrone 8, 10, 12 and 14 mg/m2 on day 1, q 21. There was a linear relationship...

journal_title：Anticancer research

authors： Repetto L,Vannozzi MO,Balleari E,Venturino A,Granetto C,Bason C,Simoni C,Prencipe E,Queirolo P,Esposito M,Ghio R,Rosso R

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:As a majority of ovarian cancer patients will ultimately develop recurrent disease, there is an urgent need for alternative or additional approaches in the treatment of this cancer. MATERIALS AND METHODS:The antitumour effect of i.p. administered cisplatin, liposomal muramyltripeptide phosphatidylethanulami...

journal_title：Anticancer research

authors： Klimp AH,De Vries EG,Scherphof GL,Daemen T

更新日期：2000-07-01 00:00:00

abstract：AIM:To assess whether prognostic factors in male (MBC) and female (FBC) breast cancer have similar impact on survival. PATIENTS AND METHODS:Charts for men and women diagnosed with breast cancer referred to the London Regional Cancer Program (LRCP) were reviewed. Patients with distant metastatic diseases were excluded....

journal_title：Anticancer research

authors： Yu E,Stitt L,Vujovic O,Joseph K,Assouline A,Au J,Younus J,Perera F,Tai P

更新日期：2013-05-01 00:00:00

abstract：:The purpose of this study was to investigate the nature of the action of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) as the modulator of gene expression. Practically, both the acceleration of daily liquid consumption following salt-hydrocortisone conditioning (sea water adaptation phenomenon) and the suppressive effec...

journal_title：Anticancer research

authors： Kodama M,Inoue F,Kodama T,Kodama M

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:In vitro studies have indicated that epidermal growth factor receptor (EGFR) may intensify signaling output by the receptor's overexpression, heterodimerization with HER-2, or autocrine expression of ligands. The purpose of the present study was to evaluate the correlation between EGFR and its related protei...

journal_title：Anticancer research

authors： Mukohara T,Kudoh S,Matsuura K,Yamauchi S,Kimura T,Yoshimura N,Kanazawa H,Hirata K,Inoue K,Wanibuchi H,Fukushima S,Yoshikawa J

更新日期：2004-01-01 00:00:00

abstract：:The circadian rhythm-modulated delivery of anticancer drugs has been shown to reduce toxicity and improve anticancer efficacy. The aim of this phase I trial was to compare the feasibility and tolerability of carboplatin (CBDCA) administered at circadian-modulated or flat infusion rate in 24 patients with advanced canc...

journal_title：Anticancer research

authors： Natoli C,Salini V,Irtelli L,Martino MT,Garufi C,Grassadonia A,Fiorentino B,Iacobelli S

更新日期：1996-05-01 00:00:00

abstract：:The effect of retinoid induced suppression of in vitro invasive ability of A549 human lung carcinoma cells on sialyltransferase activity and sialic acid content was investigated. Inhibition by retinol acetate of cell invasive potential was accompanied by a significant decrease in the enzyme activity of intact cells as...

journal_title：Anticancer research

authors： Ledinko N,Fazely F

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND/AIM:Metabolomics is widely used for biomarker discovery, but conventional mass-spectrometry extraction procedures lose the spatial localization of metabolites. In this study, we directly analyzed breast carcinoma tissues embedded in frozen tissue microarrays (fTMAs) using MALDI mass-spectrometry imaging (MAL...

journal_title：Anticancer research

authors： Torata N,Kubo M,Miura D,Ohuchida K,Mizuuchi Y,Fujimura Y,Hayakawa E,Kai M,Oda Y,Mizumoto K,Hashizume M,Nakamura M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND/AIM:Non-vascularized methods to reconstruct bone defects following tumor resection are associated with complications. As a result, the free vascularized fibular flap (FVF) has become a mainstay for reconstruction. The purpose of this study was to analyze FVF reconstruction in the upper extremity. PATIENTS A...

journal_title：Anticancer research

authors： Claxton MR,Shirley MB,Bakri K,Rose PS,Moran SL,Houdek MT

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND/AIM:Muscle relaxants, also known as neuromuscular blocking agents, can block nerve impulses to the muscles and are always used in surgery for general anesthesia. However, the effect of muscle-relaxant anesthetics on cell activity in gastric cancer is currently unknown. The present study aimed to examine and ...

journal_title：Anticancer research

authors： Jiang A,Zhao H,Liu X,Yu M,Chen J,Jiang WG

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:This case report describes a patient with symptomatic anaemia due to a bleeding duodenal metastasis from metastasising differentiated thyroid cancer (DTC), which was treated by partial duodenopancreatectomy (DP). CASE REPORT:A 71-year old male was sent to hospital with severe anaemia. This patient had suffe...

journal_title：Anticancer research

authors： Meyer A,Behrend M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Aggrecan, the large aggregating proteoglycan, is a major component of the cartilage extracellular matrix. The C-terminal globular domain (G3) of the aggrecan molecule exhibits a pattern of alternative splicing that involves three exons. Each corresponds to a subdomain, epidermal growth factor 1(EGF1), EGF2, ...

journal_title：Anticancer research

authors： Matsui Y,Araki N,Tsuboi H,Tsumaki N,Nakata K,Kawabata H,Eyre DR,Yoshikawa H

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND/AIM:γδ T cells mediate cytotoxicity against prostate cancer (PCa) cells in vitro; however, the clinical efficacy of γδ T cell-targeted immunotherapy for recurrent and metastatic PCa is unsatisfactory. We hypothesized that the resistance of recurrent and metastatic PCa to γδ T cells is related to the presence...

journal_title：Anticancer research

authors： Miyashita M,Tomogane M,Nakamura Y,Shimizu T,Fujihara A,Ukimura O,Ashihara E

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND/AIM:For cases of musculoskeletal sarcoma of the knee presenting to our institute, we prioritize joint preservation whenever possible. To investigate patient satisfaction and desire for joint preservation, a questionnaire survey was performed. PATIENTS AND METHODS:Surveys were mailed to 62 patients with musc...

journal_title：Anticancer research

authors： Abe K,Yamamoto N,Hayashi K,Takeuchi A,Kato S,Miwa S,Igarashi K,Inatani H,Aoki YU,Higuchi T,Taniguchi Y,Tsuchiya H

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Few studies have successfully established an amylase-producing lung cancer cell line or have examined its cytological, biochemical and biological features. PATIENTS AND METHODS:Cancer cells, isolated from pleural effusion using a gradient method, were cultivated. RESULTS:Amylase production from the newly e...

journal_title：Anticancer research

authors： Yokouchi H,Yamazaki K,Asahina H,Shigemura M,Moriyama T,Takaoka K,Moriya J,Itoh T,Kinoshita I,Dosaka-Akita H,Tsutsumi Y,Nishimura M

更新日期：2006-07-01 00:00:00

abstract：:Human papillomavirus (HPV)-positive tonsillar- and base of tongue cancer is increasing epidemically and has much better outcome than corresponding HPV-negative cancer and most other head and neck cancers with around 80% 3-year disease free survival with conventional radiotherapy and surgery. Consequently, most HPV-pos...

journal_title：Anticancer research

authors： Näsman A,Bersani C,Lindquist D,Du J,Ramqvist T,Dalianis T

更新日期：2017-10-01 00:00:00

abstract：:This paper reviews the properties and regulation of cation transport during the cell cycle. Extensive modulations occur in both electro-diffusional and non-electro-diffusional cation transport, most prominently during mitosis and G1 phase. These modulations can be related to compositional, structural and dynamic membr...

journal_title：Anticancer research

authors： Boonstra J,Mummery CL,van Zoelen EJ,van der Saag PT,de Laat SW

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND/AIM:Neuroendocrine neoplasms (NEN) of the female genital tract account for 2% of gynecological cancers. The aim of this study was to share our experience of 11 primary neuroendocrine neoplasms of the ovary. PATIENTS AND METHODS:All patients who presented and/or were treated at our Institution with histologi...

journal_title：Anticancer research

authors： Sehouli J,Woopen H,Pavel M,Richter R,Lauterbach LK,Taube E,Darb-Esfahani S,Fotopoulou C,Pietzner K

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND/AIM:Primary brain tumors are unique tumors due to their different pathobiological behavior, while they rarely metastasize outside the central nervous system. Regarding the oncogenesis of primary brain tumors, it was shown that changes in functions of p16 and mouse double minute 2 homolog (MDM2) are related t...

journal_title：Anticancer research

authors： Kafadar A,Küçükhüseyin Ö,Turan S,Yenilmez EN,Tunoglu S,Zeybek U,Kaynar MY,Kemerdere R,Yaylim I

更新日期：2015-07-01 00:00:00

abstract：:From 1980 to 1987, 243 evaluable patients with pT1, pT2 (less than 3 centimeters in diameter), N0, M0, invasive breast cancer were treated with "quadrantectomy" with axillary dissection followed by electron beam radiation therapy (QUART) at the St. Bortolo Hospital, Vicenza. Stage II patients received adjuvant chemoth...

journal_title：Anticancer research

authors： Gasparini G,Panizzoni GA,Dal Fior S,Germani B,Dall'Antonia F,Segato G,Meli S,Pozza F

更新日期：1991-07-01 00:00:00