A New Functional Classification of Glucuronoyl Esterases by Peptide Pattern Recognition.

abstract：:Spread and persistence of antibiotic resistance pose a severe threat to human health, yet there is still lack of knowledge about reservoirs of antibiotic resistant bacteria in the environment. We took the opportunity of the Joint Danube Survey 3 (JDS3), the world's biggest river research expedition of its kind in 2013...

journal_title：Frontiers in microbiology

authors： Kittinger C,Lipp M,Baumert R,Folli B,Koraimann G,Toplitsch D,Liebmann A,Grisold AJ,Farnleitner AH,Kirschner A,Zarfel G

更新日期：2016-05-03 00:00:00

abstract：:Modified cyclic dipeptides represent a diverse family of microbial secondary metabolites. They display a broad variety of biological and pharmacological activities and have long been recognized as privileged structures with the ability to bind to a wide range of receptors. This is due to their conformationally constra...

journal_title：Frontiers in microbiology

authors： Giessen TW,Marahiel MA

更新日期：2015-07-30 00:00:00

abstract：:Mycobacteria are able to form dormant cells, which survive for a long time without multiplication. The molecular mechanisms behind prolonged survival of dormant cells are not fully described. In particular, little information is known on biochemical processes which might take place in cells under dormancy. To gain ins...

journal_title：Frontiers in microbiology

authors： Trutneva K,Shleeva M,Nikitushkin V,Demina G,Kaprelyants A

更新日期：2018-09-04 00:00:00

abstract：:Bacterial endophytes (BEs) are non-pathogenic residents of healthy plant tissues that can confer benefits to plants. Many Bacterial endophytes have been shown to contribute to plant growth and health, alleviation of plant stress and to in-planta contaminant-degradation. This study examined the endophytic bacterial com...

journal_title：Frontiers in microbiology

authors： Lumactud R,Fulthorpe RR

更新日期：2018-08-23 00:00:00

abstract：:Adding biochar, the solid coproduct of biofuel production, to peat can enhance strawberry growth, and disease resistance against the airborne fungal pathogen Botrytis cinerea. Additionally, biochar can induce shifts in the strawberry rhizosphere microbiome. However, the moment that this biochar-mediated shift occurs i...

journal_title：Frontiers in microbiology

authors： De Tender C,Haegeman A,Vandecasteele B,Clement L,Cremelie P,Dawyndt P,Maes M,Debode J

更新日期：2016-12-22 00:00:00

abstract：:DsrAB-type dissimilatory sulfite reductase is a key enzyme of microbial sulfur-dependent energy metabolism. Sulfur oxidizers also contain DsrL, which is essential for sulfur oxidation in Allochromatium vinosum. This NAD(P)H oxidoreductase acts as physiological partner of oxidative-type rDsrAB. Recent analyses uncovere...

journal_title：Frontiers in microbiology

authors： Löffler M,Wallerang KB,Venceslau SS,Pereira IAC,Dahl C

更新日期：2020-10-16 00:00:00

abstract：:Fonsecaea pedrosoi is a dematiaceous fungus and the main causative agent of chromoblastomycosis that is a chronic disease usually affecting the human skin and subcutaneous tissues, which causes deformations and incapacities, being frequently refractory to available therapies. A typical globe-shaped, multiseptated and ...

journal_title：Frontiers in microbiology

authors： Palmeira VF,Goulart FRV,Granato MQ,Alviano DS,Alviano CS,Kneipp LF,Santos ALS

更新日期：2018-06-29 00:00:00

abstract：:Extraintestinal pathogenic Escherichia coli (ExPEC) that causes extraintestinal infections often harbor plasmids encoding fitness traits such as resistance and virulence determinants that are of clinical importance. We determined the complete nucleotide sequence of plasmid pEC302/04 from a multidrug-resistant E. coli ...

journal_title：Frontiers in microbiology

authors： Ho WS,Yap KP,Yeo CC,Rajasekaram G,Thong KL

更新日期：2016-01-11 00:00:00

abstract：:Autoimmune diseases are increasingly linked to aberrant gut microbiome and relevant metabolites. However, the association between vitiligo and the gut microbiome remains to be elucidated. Thus, we conducted a case-control study through 16S rRNA sequencing and serum untargeted-metabolomic profiling based on 30 vitiligo...

journal_title：Frontiers in microbiology

authors： Ni Q,Ye Z,Wang Y,Chen J,Zhang W,Ma C,Li K,Liu Y,Liu L,Han Z,Gao T,Jian Z,Li S,Li C

更新日期：2020-12-14 00:00:00

abstract：:While multicellular magnetotactic prokaryotes (MMPs) are ubiquitous in marine environments, the diversity of MMPs in sediments of coral reef ecosystems has rarely been reported. In this study, we made an investigation on the diversity and characteristics of MMPs in sediments at 11 stations in coral reef habitats of th...

journal_title：Frontiers in microbiology

authors： Teng Z,Zhang Y,Zhang W,Pan H,Xu J,Huang H,Xiao T,Wu LF

更新日期：2018-09-11 00:00:00

abstract：:The mechanism of DNA replication is one of the driving forces of genome evolution. Bacterial DNA polymerase III, the primary complex of DNA replication, consists of PolC and DnaE. PolC is conserved in Gram-positive bacteria, especially in the Firmicutes with low GC content, whereas DnaE is widely conserved in most Gra...

journal_title：Frontiers in microbiology

authors： Akashi M,Yoshikawa H

更新日期：2013-09-17 00:00:00

abstract：:The porcine epidemic diarrhea virus (PEDV) causes an acute and highly contagious enteric disease characterized by severe enteritis, vomiting, watery diarrhea, and a high mortality rate in seronegative neonatal piglets. In the last few years, PED had a large economic impact on the swine industries in Asia and the US, a...

journal_title：Frontiers in microbiology

authors： Bertasio C,Giacomini E,Lazzaro M,Perulli S,Papetti A,Lavazza A,Lelli D,Alborali G,Boniotti MB

更新日期：2016-12-15 00:00:00

abstract：:Platycladi Semen, which is derived from the dried ripe seed of Platycladus orientalis, has been used for the treatment of insomnia and constipation in China for 2000 years. However, it is susceptible to fungal and aflatoxin contamination under proper humidity and temperature during storage. Although aflatoxin contamin...

journal_title：Frontiers in microbiology

authors： Yu J,Guo M,Jiang W,Yang M,Pang X

更新日期：2020-10-23 00:00:00

abstract：:The regulator of citrate metabolism, CitO, from Enterococcus faecalis belongs to the FCD family within the GntR superfamily. In the presence of citrate, CitO binds to cis-acting sequences located upstream of the cit promoters inducing the expression of genes involved in citrate utilization. The quantification of the m...

journal_title：Frontiers in microbiology

authors： Blancato VS,Pagliai FA,Magni C,Gonzalez CF,Lorca GL

更新日期：2016-02-09 00:00:00

abstract：:Human settlement of Madagascar traces back to the beginning of the first millennium with the arrival of Austronesians from Southeast Asia, followed by migrations from Africa and the Middle East. Remains of these different cultural, genetic, and linguistic legacies are still present in Madagascar and other islands of t...

journal_title：Frontiers in microbiology

authors： Avanzi C,Lécorché E,Rakotomalala FA,Benjak A,Rapelanoro Rabenja F,Ramarozatovo LS,Cauchoix B,Rakoto-Andrianarivelo M,Tió-Coma M,Leal-Calvo T,Busso P,Boy-Röttger S,Chauffour A,Rasamoelina T,Andrianarison A,Sendrasoa F,Spen

更新日期：2020-05-11 00:00:00

abstract：:The intestinal microbiome is essential in humans to maintain physiological balance and nutrition metabolism. Laparoscopic cholecystectomy due to gallstone disease and cholecystitis can cause intestinal microbial dysbiosis, and following bile acid metabolism dysfunction, positions the patient at high risk of colorectal...

journal_title：Frontiers in microbiology

authors： Wang W,Wang J,Li J,Yan P,Jin Y,Zhang R,Yue W,Guo Q,Geng J

更新日期：2018-06-25 00:00:00

abstract：:There is an urgent need for new antibiotics and alternative strategies to combat multidrug-resistant bacterial pathogens, which are a growing clinical issue. Repurposing existing approved drugs with known pharmacology and toxicology is an alternative strategy to accelerate antimicrobial research and development. In th...

journal_title：Frontiers in microbiology

authors： Thangamani S,Younis W,Seleem MN

更新日期：2015-07-28 00:00:00

abstract：:Lake Fryxell, situated in the McMurdo Dry Valleys of Antarctica, is an intriguing aquatic ecosystem because of its perennial ice cover, highly stratified water column, and extreme physicochemical conditions, which collectively restrict lake biodiversity to solely microbial forms. To expand our current understanding of...

journal_title：Frontiers in microbiology

authors： Baker JM,Vander Schaaf NA,Cunningham AMG,Hang AC,Reeves CL,Huffman ER,Riester CJ,Madigan MT,Sattley WM

更新日期：2019-02-06 00:00:00

abstract：:The heterocyclic indole-alkaloid scytonemin is a sunscreen found exclusively among cyanobacteria. An 18-gene cluster is responsible for scytonemin production in Nostoc punctiforme ATCC 29133. The upstream genes scyABCDEF in the cluster are proposed to be responsible for scytonemin biosynthesis from aromatic amino acid...

journal_title：Frontiers in microbiology

authors： Ferreira D,Garcia-Pichel F

更新日期：2016-05-18 00:00:00

abstract：:The human complement system plays an important role in the defense against invading pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly activate the complement system resulting in the formation of chemoattractants and in effective labeling of the bacteria for phagocytosis. In additio...

journal_title：Frontiers in microbiology

authors： Hovingh ES,van den Broek B,Jongerius I

更新日期：2016-12-20 00:00:00

abstract：:Phage therapy requires libraries of well-characterized phages. Here we describe the generation of phage libraries for three target species: Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae. The basic phage characteristics on the isolation host, sequence analysis, growth properties, and host range and...

journal_title：Frontiers in microbiology

authors： Gibson SB,Green SI,Liu CG,Salazar KC,Clark JR,Terwilliger AL,Kaplan HB,Maresso AW,Trautner BW,Ramig RF

更新日期：2019-11-12 00:00:00

abstract：:Campylobacter as an inhabitant of the poultry gastrointestinal tract has proven to be difficult to reduce with most feed additives. In-feed antibiotics have been taken out of poultry diets due to the negative reactions of consumers along with concerns regarding the generation of antibiotic resistant bacteria. Conseque...

journal_title：Frontiers in microbiology

authors： Kim SA,Jang MJ,Kim SY,Yang Y,Pavlidis HO,Ricke SC

更新日期：2019-01-31 00:00:00

abstract：:Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated. The arenavirus Z protein facilitates production of virus-like part...

journal_title：Frontiers in microbiology

authors： Mpingabo PI,Urata S,Yasuda J

更新日期：2020-09-30 00:00:00

abstract：:Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria. It was found in previous studies that IS26 and class 1 integrons integrated on plasmids to speed the dissemination of antibiotic-r...

journal_title：Frontiers in microbiology

authors： Zhao H,Chen W,Xu X,Zhou X,Shi C

更新日期：2018-10-23 00:00:00

abstract：:Over the past decades, antimicrobial resistance (AMR) has been recognized as one of the most serious threats to public health. Although originally considered a problem to human health, the emerging crisis of AMR requires a "One Health" approach, considering human, animal, and environmental reservoirs. In this regard, ...

journal_title：Frontiers in microbiology

authors： Rubiola S,Chiesa F,Dalmasso A,Di Ciccio P,Civera T

更新日期：2020-08-26 00:00:00

abstract：:The complexity of the pathogenesis of inflammatory bowel disease (ulcerative colitis and Crohn's disease) has led to the quest of empirically drug therapies, combining immunosuppressant agents, biological therapy and modulators of the microbiota. Helminth parasites have been proposed as an alternative treatment of the...

journal_title：Frontiers in microbiology

authors： Roig J,Saiz ML,Galiano A,Trelis M,Cantalapiedra F,Monteagudo C,Giner E,Giner RM,Recio MC,Bernal D,Sánchez-Madrid F,Marcilla A

更新日期：2018-05-23 00:00:00

abstract：:In the fast-growing Escherichia coli cells, RNA polymerase (RNAP) molecules are concentrated and form foci at clusters of ribosomal RNA (rRNA) operons resembling eukaryotic nucleolus. The bacterial nucleolus-like organization, spatially compartmentalized at the surface of the compact bacterial chromosome (nucleoid), s...

journal_title：Frontiers in microbiology

authors： Mata Martin C,Sun Z,Zhou YN,Jin DJ

更新日期：2018-06-05 00:00:00

abstract：:During cystic fibrosis (CF) chronic lung infections, bacteria of the Burkholderia cepacia complex (Bcc) are exposed for several years to a stressful and changing environment. These environmental challenges results in genetic changes of the initial infecting strain with the consequent diversification of genotypes and p...

journal_title：Frontiers in microbiology

authors： Moreira AS,Lourenço AB,Sá-Correia I

更新日期：2016-12-20 00:00:00

abstract：:Yersinia pestis, responsible for causing fulminant plague, has evolved clonally from the enteric pathogen, Y. pseudotuberculosis, which in contrast, causes a relatively benign enteric illness. An ~97% nucleotide identity over 75% of their shared protein coding genes is maintained between these two pathogens, leaving m...

journal_title：Frontiers in microbiology

authors： Martínez-Chavarría LC,Vadyvaloo V

更新日期：2015-09-17 00:00:00

abstract：:Bacteriophage endolysins and bacterial exolysins are capable of enzymatic degradation of the cell wall peptidoglycan layer and thus show promise as a new class of antimicrobials. Both exolysins and endolysins often consist of different modules, which are responsible for enzymatic functions and cell wall binding, respe...

journal_title：Frontiers in microbiology

authors： Hjelm LC,Nilvebrant J,Nygren PÅ,Nilsson AS,Seijsing J

更新日期：2019-03-22 00:00:00