Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion.

abstract：:RNA silencing, an evolutionarily conserved and sequence-specific gene-inactivation system, has a pivotal role in antiviral defense in most eukaryotic organisms. In plants, a class of exogenous small RNAs (sRNAs) originating from the infecting virus called virus-derived small interfering RNAs (vsiRNAs) are predominantl...

journal_title：Frontiers in microbiology

authors： Zhang C,Wu Z,Li Y,Wu J

更新日期：2015-11-09 00:00:00

abstract：:The rumen contains a multi-kingdom, commensal microbiome, including protozoa, bacteria, archaea, fungi and viruses, which enables ruminant herbivores to ferment and utilize plant feedstuffs that would be otherwise indigestible. Within the rumen, virus populations are diverse and highly abundant, often out-numbering th...

journal_title：Frontiers in microbiology

authors： Gilbert RA,Townsend EM,Crew KS,Hitch TCA,Friedersdorff JCA,Creevey CJ,Pope PB,Ouwerkerk D,Jameson E

更新日期：2020-03-26 00:00:00

abstract：:Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide epidemic. Among the different environmental factors, the gut microbiota is now considered as a key player interfering with energy metabolism and host susceptibility to several non-communicable diseases. Among the next-generation be...

journal_title：Frontiers in microbiology

authors： Cani PD,de Vos WM

更新日期：2017-09-22 00:00:00

abstract：:Bacterial cells are surrounded by an exoskeleton-like structure, the cell wall, composed primarily of the peptidoglycan (PG) sacculus. This structure is made up of glycan strands cross-linked by short peptides generating a covalent mesh that shapes bacteria and prevents their lysis due to their high internal osmotic p...

journal_title：Frontiers in microbiology

authors： Yadav AK,Espaillat A,Cava F

更新日期：2018-08-31 00:00:00

abstract：:The marine picocyanobacterium Synechococcus sp. WH7803 possesses two glutamine synthetases (GSs; EC 6.3.1.2), GSI encoded by glnA and GSIII encoded by glnN. This is the first work addressing the physiological regulation of both enzymes in a marine cyanobacterial strain. The increase of GS activity upon nitrogen starva...

journal_title：Frontiers in microbiology

authors： Domínguez-Martín MA,Díez J,García-Fernández JM

更新日期：2016-06-28 00:00:00

abstract：:Snow algae blooms contain bacteria, fungi, and other microscopic organisms. We surveyed 55 alpine snow algae blooms, collecting a total of 68 samples, from 12 mountains in the Coast Range of British Columbia, Canada. We used microscopy and rDNA metabarcoding to document biodiversity and query species and taxonomic ass...

journal_title：Frontiers in microbiology

authors： Yakimovich KM,Engstrom CB,Quarmby LM

更新日期：2020-07-28 00:00:00

abstract：:Leishmaniasis comprises a spectrum of parasitic diseases caused by protozoans of the genus Leishmania. Molecular tools have been widely employed for the detection of Leishmania due to its high sensitivity and specificity. However, the analytical performance of molecular platforms as PCR and real time PCR (qPCR) includ...

journal_title：Frontiers in microbiology

authors： León CM,Muñoz M,Hernández C,Ayala MS,Flórez C,Teherán A,Cubides JR,Ramírez JD

更新日期：2017-10-04 00:00:00

abstract：:Aluminum (Al)-resistant plant cultivars can recruit beneficial microbes to alleviate the stresses. However, the mechanism of how rhizobacterial communities strengthen Al tolerance of wild soybean has not been addressed. The aim of this study was to investigate the bacterial community structure in the rhizosphere of Al...

journal_title：Frontiers in microbiology

authors： Shi Q,Jin J,Liu Y,Zhang Y,Cai Z,Ma Q,Cheng Y,Wen R,Nian H,Lian T

更新日期：2020-08-19 00:00:00

abstract：:The deadwood mycobiome, also known as wood-inhabiting fungi (WIF), are among the key players in wood decomposition, having a large impact on nutrient cycling in forest soils. However, our knowledge of WIF richness and distribution patterns in different forest biomes is limited. Here, we used pyrotag sequencing of the ...

journal_title：Frontiers in microbiology

authors： Purahong W,Pietsch KA,Lentendu G,Schöps R,Bruelheide H,Wirth C,Buscot F,Wubet T

更新日期：2017-04-19 00:00:00

abstract：:Fluoroquinolone resistance can cause major clinical problems. Here, we investigated fluoroquinolone resistance mechanisms in a clinical Escherichia coli isolate, HUE1, which had no mutations quinolone resistance-determining regions (QRDRs) of DNA gyrase and topoisomerase IV. HUE1 demonstrated MICs that exceeded the br...

journal_title：Frontiers in microbiology

authors： Sato T,Yokota S,Uchida I,Okubo T,Usui M,Kusumoto M,Akiba M,Fujii N,Tamura Y

更新日期：2013-05-24 00:00:00

abstract：:Group B Streptococcus (GBS; Streptococcus agalactiae) is a leading cause of sepsis in neonates and pregnant mothers worldwide. Whereas the hyper-virulent serogroup III clonal cluster 17 has been associated with neonatal disease and meningitis, serogroup III ST283 was recently implicated in invasive disease among non-p...

journal_title：Frontiers in microbiology

authors： Yang Y,Luo M,Zhou H,Li C,Luk A,Zhao G,Fung K,Ip M

更新日期：2019-01-23 00:00:00

abstract：:The term microbiome describes the genetic material encoding the various microbial populations that inhabit our body. Whilst colonization of various body niches (e.g., the gut) by dynamic communities of microorganisms is now universally accepted, the existence of microbial populations in other "classically sterile" loc...

journal_title：Frontiers in microbiology

authors： Whittle E,Leonard MO,Harrison R,Gant TW,Tonge DP

更新日期：2019-01-17 00:00:00

abstract：:Evolution of fungicide resistance in plant pathogens is one of major concerns in sustainable plant disease management. In this study, the genetics and potential of developing resistance to a demethylation inhibitor (DMI) fungicide, difenoconazole, in the fungal pathogen Alternaria alternata was investigated using a co...

journal_title：Frontiers in microbiology

authors： He MH,Wang YP,Wu EJ,Shen LL,Yang LN,Wang T,Shang LP,Zhu W,Zhan J

更新日期：2019-07-10 00:00:00

abstract：:Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion of ergosterol. Usi...

journal_title：Frontiers in microbiology

authors： Hu C,Zhou M,Wang W,Sun X,Yarden O,Li S

更新日期：2018-01-17 00:00:00

abstract：:During the pre-erythrocytic asymptomatic phase of malarial infection, sporozoites develop transiently inside less than 100 hepatocytes that subsequently release thousands of merozoites. Killing of these hepatocytes by cytotoxic T cells (CTLs) confers protection to subsequent malarial infection, suggesting that this bo...

journal_title：Frontiers in microbiology

authors： Bertolino P,Bowen DG

更新日期：2015-02-18 00:00:00

abstract：:Infections that result in natural or manmade spread of lethal biological agents are a concern and require national and focused preparedness. In this manuscript, as part of an early diagnostics and pathogen treatment strategy, we have focused on extracellular vesicles (EVs) that arise following infections. Although the...

journal_title：Frontiers in microbiology

authors： Schwab A,Meyering SS,Lepene B,Iordanskiy S,van Hoek ML,Hakami RM,Kashanchi F

更新日期：2015-10-20 00:00:00

abstract：:Francisella tularensis is the causative agent of a spectrum of diseases collectively known as tularemia. The extreme virulence of the pathogen in humans, combined with the low infectious dose and the ease of dissemination by aerosol have led to concerns about its abuse as a bioweapon. Until recently, nothing was known...

journal_title：Frontiers in microbiology

authors： Kilmury SL,Twine SM

更新日期：2011-01-07 00:00:00

abstract：:Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable. Novel anti-virulence strategies will undoubtedly provide a path forward in combating these resistant bacterial infections. Sortase A (SrtA), an enzyme responsi...

journal_title：Frontiers in microbiology

authors： Zhang B,Teng Z,Li X,Lu G,Deng X,Niu X,Wang J

更新日期：2017-09-06 00:00:00

abstract：:Bacteria often exist in polymicrobial communities where they compete for limited resources. Intrinsic to this competition is the ability of some species to inhibit or kill their competitors. This phenomenon is pervasive throughout the human body where commensal bacteria block the colonization of incoming microorganism...

journal_title：Frontiers in microbiology

authors： Hardy BL,Bansal G,Hewlett KH,Arora A,Schaffer SD,Kamau E,Bennett JW,Merrell DS

更新日期：2020-01-15 00:00:00

abstract：:Genitourinary syndrome of menopause (GSM) is a chronic and progressive condition with a series of vulvovaginal, sexual, and lower urinary tract discomforts, mainly due to hypoestrogenism. Menopausal hormone therapy (MHT) has generally been considered as the most effective treatment for GSM. In addition, vaginal microb...

journal_title：Frontiers in microbiology

authors： Geng L,Huang W,Jiang S,Zheng Y,Zhou Y,Zhou Y,Hu J,Li P,Tao M

更新日期：2020-11-20 00:00:00

abstract：:Engineered nanoparticles have provided a basis for innovative agricultural applications, specifically in plant disease management. In this interdisciplinary study, by conducting comparison studies using macroscale magnesium oxide (mMgO), we evaluated the fungicidal activity of MgO nanoparticles (nMgO) against soilborn...

journal_title：Frontiers in microbiology

authors： Chen J,Wu L,Lu M,Lu S,Li Z,Ding W

更新日期：2020-03-12 00:00:00

abstract：:Recent research has proven the ability of cold atmospheric plasma (CAP) for assuring food safety. A more flexible and transportable alternative is the use of plasma activated liquids (PAL), which are also known to have antimicrobial properties. However, within the context of food safety, little is known on its potenti...

journal_title：Frontiers in microbiology

authors： Smet C,Govaert M,Kyrylenko A,Easdani M,Walsh JL,Van Impe JF

更新日期：2019-07-04 00:00:00

abstract：:Acute respiratory infection (ARI) is the most frequent cause for hospitalization in infants and young children. Using multiplexed nCounter technology to digitally quantify 600 human mRNAs in parallel with 14 virus- and 5 bacterium-specific RNAs, we characterized viral and bacterial presence in nasopharyngeal aspirates...

journal_title：Frontiers in microbiology

authors： Fukutani KF,Nascimento-Carvalho CM,Bouzas ML,Oliveira JR,Barral A,Dierckx T,Khouri R,Nakaya HI,Andrade BB,Van Weyenbergh J,de Oliveira CI

更新日期：2018-11-09 00:00:00

abstract：:Photorhabdus luminescens TTO1 and Xenorhabdus nematophila HGB081 are insect pathogenic bacteria and producers of various structurally diverse bioactive natural products. In these entomopathogenic bacteria we investigated the role of the global regulators Lrp, LeuO, and HexA in the production of natural products. Lrp i...

journal_title：Frontiers in microbiology

authors： Engel Y,Windhorst C,Lu X,Goodrich-Blair H,Bode HB

更新日期：2017-02-17 00:00:00

abstract：:Objectives:Candida species are a major cause of hospital infections, including ocular candidiasis, but few studies have examined the propensities of specific species to invade the eye or the unique immunological responses induced. This study examined the frequency and characteristics of species-specific Candida eye in...

journal_title：Frontiers in microbiology

authors： Abe M,Kinjo Y,Ueno K,Takatsuka S,Nakamura S,Ogura S,Kimura M,Araoka H,Sadamoto S,Shinozaki M,Shibuya K,Yoneyama A,Kaku M,Miyazaki Y

更新日期：2018-10-17 00:00:00

abstract：:Candida glabrata is an increasingly important cause of invasive candidiasis. In China, relatively little is known of the molecular epidemiology of C. glabrata and of its antifungal susceptibility patterns. Here we studied 411 non-duplicate C. glabrata isolates from 411 patients at 11 hospitals participating in the Nat...

journal_title：Frontiers in microbiology

authors： Hou X,Xiao M,Chen SC,Kong F,Wang H,Chu YZ,Kang M,Sun ZY,Hu ZD,Li RY,Lu J,Liao K,Hu TS,Ni YX,Zou GL,Zhang G,Fan X,Zhao YP,Xu YC

更新日期：2017-05-23 00:00:00

abstract：:In this study, Taisui TS-2007S, a previously unidentified biological object discovered in soil in China, was identified. TS-2007S was shown to contain abundant carbohydrates but a scarcity of protein, fat, and minerals. The exopolymers of TS-2007S showed FT-IR spectra that were similar to those of xanthan gum (XG) but...

journal_title：Frontiers in microbiology

authors： Su T,Liu H,Zhang C,Shang D,Wang C,Qiu L

更新日期：2020-11-11 00:00:00

abstract：:Epstein-Barr virus (EBV) is a ubiquitous human γ-herpes virus which establishes a life-long asymptomatic infection in immunocompetent hosts. In human immunodeficiency virus type 1 (HIV-1) infected patients, the impaired immunosurveillance against EBV may favor the development of EBV-related diseases, ranging from lymp...

journal_title：Frontiers in microbiology

authors： Petrara MR,Freguja R,Gianesin K,Zanchetta M,De Rossi A

更新日期：2013-10-18 00:00:00

abstract：:Antimicrobial resistance represents one of the greatest challenges of the twenty-first century, and it is globally recognized that addressing this problem requires a concerted One Health approach involving humans, animals, and the environment. Methicillin-resistant Staphylococcus aureus (MRSA) currently represents a g...

journal_title：Frontiers in microbiology

authors： Correia S,Silva V,García-Díez J,Teixeira P,Pimenta K,Pereira JE,Oliveira S,Rocha J,Manaia CM,Igrejas G,Poeta P

更新日期：2019-12-18 00:00:00

abstract：:Despite recent recognition of the ATP-binding cassette protein OptrA as an important mediator of linezolid resistance in Enterococcus faecalis worldwide, the mechanisms of optrA gene acquisition and transfer remain poorly understood. In this study, we performed comprehensive molecular and phenotypic profiling of 44 op...

journal_title：Frontiers in microbiology

authors： Zou J,Tang Z,Yan J,Liu H,Chen Y,Zhang D,Zhao J,Tang Y,Zhang J,Xia Y

更新日期：2020-06-04 00:00:00