Abstract：
:In the last decade, numerous epidemiological, clinical and experimental data show that periconceptional, perinatal and postnatal environment determines the offspring's risk for later-life chronic disease. For this phenomenon, the term "fetal" or "perinatal programming" is used. In exposed offspring already in childhood and early adulthood, metabolic and cardiovascular changes can be observed, leading to obesity, diabetes and hypertension. Nowadays, the mode of conception (e.g., in vitro fertilization), maternal metabolic conditions (e.g., undernutrition, overnutrition, diabetes) and complications during pregnancy (e.g., preeclampsia, intrauterine growth restriction) are suspected to be negative predictors for offspring's long-term health. Mechanisms responsible for these effects still remain mainly unclear, but include epigenetic, transcriptional, endoplasmic reticulum stress, and reactive oxygen species. This review presents a piece of the puzzle with regards to periconceptional and early perinatal conditions determining later-life risk for chronic adult disease.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
von Ehr J,von Versen-Höynck Fdoi
10.1007/s00404-016-4178-7subject
Has Abstractpub_date
2016-10-01 00:00:00pages
673-9issue
4eissn
0932-0067issn
1432-0711pii
10.1007/s00404-016-4178-7journal_volume
294pub_type
杂志文章,评审abstract：PURPOSE:To investigate the influence of different kinds of endometriotic lesions, especially peritoneal endometriotic implants in pain generation and the pain reduction after surgical excision in a prospective study. METHODS:Fifty-one pre-menopausal patients underwent surgical laparoscopy due to chronic pelvic pain, d...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00404-008-0921-z
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:Pentraxin 3 (PTX3) is a locally secreted, quicker responsive pro-inflammatory protein than C-reactive protein (CRP). We evaluated the value of PTX3 in the prediction of ovarian hyperstimulation syndrome (OHSS), a severe complication of in vitro fertilization (IVF). METHODS:This two-year prospective follow-up s...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05556-9
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Data on comparative outcomes of abdominal myomectomy for varying uterine sizes that could guide informed decision by women and clinicians in resource-constrained settings are scarce. OBJECTIVE:To evaluate safety of abdominal myomectomy and compare perioperative morbidities for women with very large uterine ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1460-y
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:To evaluate the effect of perioperative blood transfusions on the risk of recurrence of endometrial cancer. METHODS:This study is a retrospective analysis of 358 consecutive patients, without a history of other tumors, who underwent surgery for endometrial cancer between January 2000 and April 2010. RESULTS:W...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2668-9
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:We aimed to evaluate the effect of an absorbable adhesion barrier (oxidized regenerated cellulose) for the prevention of peritoneal adhesions in women undergoing repeat cesarean delivery (CD). METHODS:This is a retrospective, single center study that included all women who underwent two consecutive CDs, 2011-2...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05591-6
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Cardiac tamponade caused by gynecologic malignancies are extremely rare. CASE:A 56-year-old woman was referred to our hospital with vaginal bleeding and abdominal distension. Computed tomography showed massive peritoneal fluid, peritoneal dissemination, swelling of the paraaortic lymph nodes and liver metas...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0701-9
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:To compare the operative data and early postoperative outcomes of total laparoscopic hysterectomy (TLH), laparoscopically assisted vaginal hysterectomy (LAVH) and vaginal hysterectomy (VH). METHODS:One hundred and eight women requiring hysterectomy for enlarged myomatous uterus were randomly allocated into thr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-014-3228-2
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:This study is designed to explore the correlation between AMH levels and IR in normal weight PCOS women. MATERIALS AND METHODS:This prospective study was conducted on 55 patients, who were admitted to obstetrics and gynecology department of a university clinic. Study group was consisted of 34 patients diagnose...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2833-9
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Hysterectomies are preformed abdominally, vaginally, laparoscopic or with robotic assistance. When choosing the route of hysterectomy, the physician should take into consideration the safest and most cost-effective route to fulfill all needs of the patient. METHODS:Data were collected retrospectively from 9...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3594-9
更新日期：2015-07-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of intravenous ferric carboxymaltose administration to pregnant women with varying severities of iron deficiency anemia and iron deficiency without anemia. METHODS:In this prospective observational study of local obstetric practice, we analyzed data from 863 pregnant women w...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4782-9
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:To assess the impact of three-dimensional (3D) versus two-dimensional (2D) ultrasound (US) on maternal-fetal bonding. STUDY DESIGN:Prospective randomized pilot study among low risk women with singleton fetuses in the second and third trimester. Dependent on the randomization pattern, US was commenced either ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-007-0368-7
更新日期：2007-11-01 00:00:00
abstract：:The current management of patients with cervical polyps may include different approaches and protocols, such as a simply removal of the polyp in most cases at an office setting, surgical dilatation and curettage, electrosurgical excision or hysteroscopic polypectomy. Exploration of the cervical canal and uterine cavit...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-007-0417-2
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:We aimed to investigate the impact of early versus late discharge following cesarean delivery (CD) on re-admission rate. METHODS:This is a retrospective cohort study of all CDs performed between 2013 and 2016. Patients who underwent CD between 01/13 and 12/14, were routinely discharged on postoperative day (PO...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4828-z
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:Aggressive angiomyxoma (AAM) is a rare and often misdiagnosed tumor that is characterized by frequent local recurrences. This study aimed to investigate the clinicopathological characteristics, surgical experiences, and prognosis for aggressive angiomyxoma to improve the accuracy of diagnosis and develop treatm...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-020-05592-5
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To investigate the level of cytokines and immune cells in the peripheral blood (PB) and peritoneal fluid (PF) of different stages of endometriosis. METHODS:A prospective study was conducted to include 97 women with (n 60) and without (n 37) histopathologically confirmed endometriosis. Based on rASRM classifi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0844-8
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:To investigate the role of epigenetic inactivation of hMLH1 during the malignant transformation of ovarian endometriosis (EMs), and to explore the relationship between the epigenetic inactivation of hMLH1 in eutopic endometria and the malignant transformation of ovarian EMs. METHODS:The target tissue from 29 c...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1922-x
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Hand and wrist complaints can decrease the quality of life of pregnant women, which can occur or aggravate during pregnancy and advance to chronic state if left untreated. The purpose of this study was to describe hand and wrist complaints in relation to pregnancy and assess their significance in pregnancy. ME...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3244-2
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:Congenital HCMV infection affects about 0.5-0.9 % of newborns in Europe. Primary prevention could effectively be implemented in screening programmes for couples treated for infertility. By supplying epidemiological data, the proportion of women susceptible to primary HCMV infection is estimated. METHODS:Retros...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3640-2
更新日期：2015-08-01 00:00:00
abstract：:We have examined the predictive value of measurements of CASA (Cancer Associated Serum Antigen) levels in patients with breast carcinoma. The measurement uses monoclonal antibodies that bind to an epitope on the polymorphic epithelial mucin. CASA levels were of less value compared with the levels of other tumor marker...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s004040050215
更新日期：1998-01-01 00:00:00
abstract：:Diet may act as a cofactor in the development of cancer of the cervix. A consistent correlation exists between low tissue concentrations, low serum level, and low intake of vitamin A, beta-carotene, vitamin C, or folic acid and an increased prevalence of cervical neoplasia. A moderate effect is seen in clinical trials...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/BF00933072
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:To study the anti-oxidant properties of neem (Azadirachta indica) in inducing apoptosis of cervical cancer cells and estimation of caspase activity and TNF-α and IFN-γ levels in monocytes of cervical cancer patients and controls. METHODS:Monocytes were cultured from blood samples of 65 study cases and 30 contr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2428-x
更新日期：2012-11-01 00:00:00
abstract：:We here report a case of trisomy 21 with congenital chylothorax. The patient was a male newborn who had been diagnosed as having trisomy 21 with congenital chylothorax. This is the fifth case of the both conditions in English literature. Congenital chylothorax is very rare in a trisomy 21 patient. There, however, may ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02389608
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To assess the main neonatal morbidity results in relation to induced labour indications. METHODS:Historical groups from a total of 3,817 deliveries over a three year period (2009, 2010 and 2011) in "Mancha-Centro" Hospital (Alcázar de San Juan) formed the study group. All programmed and non-avoidable caesarean...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3349-7
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Recent studies show that contrast-enhanced ultrasonography (CEUS) using SonoVue has the potential to improve the performance of sentinel lymph node biopsy (SLNB) in patients with early breast cancer. However, the evidence of SLNB using CEUS in patients converting from cN1 to cN0 after neoadjuvant chemotherap...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05646-8
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:Since the first description about oxygen toxicity made by Joseph Priestley, the oxidative stress has been enrolled as a key factor in the pathogenesis of endometriosis. Our aim was to review oxidative stress biomarkers measured in patients with endometriosis. METHODS:Relevant studies were identified by searche...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-012-2439-7
更新日期：2012-10-01 00:00:00
abstract：:We describe a postmenopausal woman with 45,XO/46,XX/47,XXX mosaicism who presented with a Sertoli-Leydig cell tumour and a past history of habitual abortion. The cytogenetic finding is discussed in relation to the etiology of the tumour and of the recurrent abortions. ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00932978
更新日期：1988-01-01 00:00:00
abstract：PURPOSE OF REVIEW:The objective of this article is to review the recently published literature on the use of minimally invasive surgical approaches for patients with endometrial cancer. METHODS:Narrative review of the pertinent literature on traditional laparoscopy and robotically assisted laparoscopy for the treatmen...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-014-3517-9
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:In case of non-gynecological solid tumors and hematological malignancies diagnosed during pregnancy, individual diagnostic and treatment options must be established by an interdisciplinary team. METHODS:In part II of the present review we report on diagnostic and therapeutic principles in distinct entities of ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-011-2059-7
更新日期：2011-12-01 00:00:00
abstract：METHODS:The maternal and fetal outcomes of 55 pregnancies in 24 patients with pre-existing lupus nephritis (LN) were retrospectively analysed. The risk factors for poor fetal outcome were evaluated. The patients were divided into two groups. Patients in Group A had quiescent LN and those in Group B showed clinical evid...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-003-0574-x
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:Effective cytotoxic treatment options for advanced cervical cancer are exceedingly limited. Therefore, interest has increased in targeted therapeutics for the treatment of cervical cancer. Cetuximab, a monoclonal antibody, binds specifically to the epidermal growth factor receptor (EGFR) and competitively inh...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1389-1
更新日期：2011-01-01 00:00:00
