Abstract:
OBJECTIVE:We have studied cross-shift respiratory responses of several individual bioaerosol components of the dust in the grain and feed industry in Norway. METHODS:Cross-shift changes in lung function and nasal congestion, as well as in respiratory and systemic symptoms of 56 exposed workers and 36 referents, were recorded on the same day as full-shift exposure to the inhalable aerosol fraction was assessed. Exposure-response associations were investigated by regression analysis. RESULTS:The workers were exposed on average to 1.0 mg/m(3) of grain dust, 440 EU/m(3) of endotoxin, 6 µg/m(3) of β-1,3-glucans, 17×10(4)/m(3) of bacteria and 4×10(4)/m(3) of fungal spores during work. The exposure was associated with higher prevalence of self-reported eye and airway symptoms, which were related to the individual microbial components in a complex manner. Fatigue and nose symptoms were strongest associated with fungal spores, cough with or without phlegm was associated with grain dust and fungal spores equally strong and wheeze/tight chest/dyspnoea was strongest associated with grain dust. Bioaerosol exposure did not lead to cross-shift lung function decline, but several microbial components had influence on nose congestion. CONCLUSIONS:Exposure to fungal spores and dust showed stronger associations with respiratory symptoms and fatigue than endotoxin exposure. The associations with dust suggest that there are other components in dust than the ones studied that induce these effects.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Straumfors A,Heldal KK,Eduard W,Wouters IM,Ellingsen DG,Skogstad Mdoi
10.1136/oemed-2015-103438subject
Has Abstractpub_date
2016-10-01 00:00:00pages
685-93issue
10eissn
1351-0711issn
1470-7926pii
oemed-2015-103438journal_volume
73pub_type
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
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doi:10.1136/oem.2010.055020
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
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更新日期:2018-05-01 00:00:00
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doi:10.1136/oem.56.1.10
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.7.482
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更新日期:2010-09-01 00:00:00
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更新日期:2019-05-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.6.386
更新日期:1994-06-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:
更新日期:2004-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2008-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-09-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2018-105604
更新日期:2019-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
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更新日期:2006-10-01 00:00:00