Bladder cancer and occupation: a case-control study in northern Italy.

Abstract:

OBJECTIVES:A hospital based case-control study was conducted between 1992 and 1993 in the province of Brescia, a highly industrialised area in northern Italy, to evaluate occupational risk factors of bladder cancer. METHODS:The study evaluated 355 histologically confirmed cases of bladder cancer (275 men, 80 women) and 579 controls affected by urological non-neoplastic diseases (397 men, 182 women). Lifetime occupational history, smoking and drinking habits, and sociodemographic characteristics were recorded by means of a structured questionnaire. Odds ratios (ORs) were computed with adjustment for age, smoking, alcohol and coffee consumption, education, and place of residence. RESULTS:A significant (P < 0.05) increase of risk of bladder cancer were found in men for labourers in the construction industry (OR 2.1, 95% confidence interval (95% CI) 1.1-3.9) and for recreational and cultural services (OR 5.0, 95% CI 1.3-18.9). Increased risks, although not significant, were found for various other occupations and industries such as machinery mechanics, metal processers and polishers, blacksmiths, gunsmiths, painters; for transport workers, an increased risk with increasing duration of employment was found. CONCLUSIONS:Occupational exposures seem to contribute to bladder cancer risk in the area under study.

journal_name

Occup Environ Med

authors

Porru S,Aulenti V,Donato F,Boffetta P,Fazioli R,Cosciani Cunico S,Alessio L

doi

10.1136/oem.53.1.6

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

6-10

issue

1

eissn

1351-0711

issn

1470-7926

journal_volume

53

pub_type

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