The relationship between dispositional empathy and prefrontal cortical functioning in patients with frontal lobe epilepsy.

Abstract:

BACKGROUND & OBJECTIVE:Rehabilitation focuses brain-behavior relationship which highlights interaction between psychological and neurobiological factors for better patient care. There is a missing link in the literature about socio-cognitive aspects of frontal lobe epilepsy. Our objective was to examine prefrontal cortical functioning (PCF) and empathic abilities in patients with frontal lobe epilepsy (FLE). Further, we analyzed whether any relationship between components of dispositional empathy and PCF exists in patients with FLE. METHODS:The study was designed in an experimental paradigm. Sixty patients with FLE were recruited from Sheikh Zayed and Jinnah hospital, Pakistan. Sixty healthy individuals in response to an advertisement took part in the study as control subjects. Participants completed interpersonal reactivity index. Following they performed clock drawing test and word-color identification task switching experiment. RESULT:Patients with FLE demonstrated weaker PCF (i.e., cognitive flexibility and executive function) as compared to healthy control subjects. Patients with FLE scored lesser on cognitive empathy as compared to healthy control subjects. On contrary, there was no significant difference between patient and control group on affective empathy. Cognitive not affective empathy was potential predictor of PCF. CONCLUSION:Cognitive empathy is a significant marker of prefrontal cortical functioning (PCF) in FLE. Higher cognitive empathy would lead to efficient PCF.

journal_name

Pak J Med Sci

authors

Gul A,Ahmad H

doi

10.12669/pjms.331.11742

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

200-204

issue

1

eissn

1682-024X

issn

1681-715X

pii

PJMS-33-200

journal_volume

33

pub_type

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