Abstract：
:PTSD is a disorder of emotion dysregulation. Although much work has intended to elucidate the neural underpinnings of the disorder, much remains unknown about the neurobiological substrates of emotion dysregulation in PTSD. In order to assess the relationship between a neural measure of attention to emotion (i.e. the late positive potential; LPP) and PTSD symptoms, EEG was recorded and examined as a potential predictor of military-related PTSD symptoms in a sample of 73 OEF/OIF/OND veterans. Results revealed that higher PTSD symptoms were related to an attenuated LPP response to angry facial expressions. This finding was not observed for happy or fearful faces. The current study provides initial evidence that, in a relatively young, mostly male sample of OEF/OIF/OND veterans, hyporeactivity to angry faces at the neural level may provide phenotypic data to characterize individual differences in PTSD symptom severity. This work may assist in future studies that seek to examine useful psychophysiologic targets for treatment and early interventions.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
DiGangi JA,Burkhouse KL,Aase DM,Babione JM,Schroth C,Kennedy AE,Greenstein JE,Proescher E,Phan KLdoi
10.1016/j.jpsychires.2017.03.013subject
Has Abstractpub_date
2017-09-01 00:00:00pages
132-138eissn
0022-3956issn
1879-1379pii
S0022-3956(17)30087-0journal_volume
92pub_type
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