Abstract:
:The development of active Ca channels was studied in progenitors of chick dorsal root ganglion (DRG) cells. These were isolated using neuron and glia specific antibodies which killed differentiated cells. The low voltage activated, completely inactivating (LVA) Ca channel was found to be expressed first amongst channels carrying inward currents and thus providing substrates of excitability. The more ubiquitous high voltage activated and incompletely inactivating (HVA) Ca channel as well as the Tetrodotoxin-sensitive Na current appeared with a delay of about one half day. A similar time course of Ca-, but not Na-channel-expression was found in a parasympathetic preparation. Ca channels appear early and preferentially incorporated in growth zones of sprouting cells which may point to some function in the growth process. Incorporation is not directly promoted by nerve growth factor as shown in PC12 (pheochromocytoma) cells since it follows growth with considerable delay. LVA Ca channels are not expressed in this sympathetic cell line but in DRG cells they were observed to remain localized in the soma region. Such pattern in distribution was also concluded from results on rat hippocampal neurons and suggests different functional commitment of the Ca channel species.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
Lux HDsubject
Has Abstractpub_date
1988-08-01 00:00:00pages
116-21issue
2eissn
0738-0658issn
2373-6011journal_volume
7pub_type
杂志文章abstract:OBJECTIVE:Skin biomechanics are physical properties that protect the body from injury. Little is known about differences in skin biomechanics in racial/ethnic groups and the role of skin color in these differences. The purpose of this study was to determine the relationship between skin biomechanics (viscoelasticity, h...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:Fungal spores are ubiquitous in the atmosphere worldwide, but their distribution is not homogeneous at different locations. Most studies have compared airborne fungal spores ecology in temperate zones, but less is known about the tropics. METHODS:This study compared, through statistical analysis of archived ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2020-09-01 00:00:00
abstract::Rat gene 33 (g33) mRNA has a widespread tissue distribution. Insulin and various agents such as glucocorticoids, phorbol esters and plant lectins regulate G33 expression in rat hepatoma cells. The regulation of g33 by insulin and a phorbol ester was examined in two Chinese Hamster ovary (CHO) cell lines, CHO-T cells (...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::The world has encountered a new and serious epidemic which has disproportionately affected fetuses and infants. What makes the Zika virus (ZIKV) epidemic such a threat in our times, is that a whole generation can be affected by birth defects caused by a seemingly innocuous maternal infection, which in most cases go un...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:Dental caries is one of the most prevalent chronic diseases in children. Currently, no data are available on dental caries prevalence in the Dominican Republic. The purpose of this study was to estimate the prevalence of dental caries in schoolattending 12-year-olds in San Pedro de Macorís, Dominican Republic...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:People with type 1 diabetes (T1D) may experience significant changes in their daily routines due to this condition, which frequently results in depressive symptoms and the deterioration of their quality of life. We examined the factors associated with suicidal ideation (SI) and diabetes-related quality of lif...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:Shunt infection is the most common complication following a Cerebrospinal fluid (CSF) diversion procedure with devastating consequences. This study analyzes the efficacy of different shunt systems in reducing early shunt infections in the pediatric population. METHODS:Retrospective case study analysis of 177...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the role of gender on HIV/AIDS stigma among 507 medical students in Puerto Rico. METHODS:A secondary data analysis was performed with baseline measurements of a controlled randomized study. RESULTS:Unadjusted analyses showed that the overall multivariate test for gender was signif...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To examine the relationship of the symptoms of diarrhea and fatigue by testing a model that included multiple dimensions of the cancer related-symptom experience. METHODS:A secondary data analysis was conducted on data from the self-reports of 102 cancer patients co experiencing diarrhea and fatigue during t...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2019-06-01 00:00:00
abstract::Exposure to lead in children living on a former landfill in Vega Baja-Puerto Rico, a United States Environmental Protection Agency (USEPA) designated Superfund Site, is a major health concern. Direct contact with lead-contaminated soil is considered a major exposure source. However, there is a lack of information rega...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To compare the effectiveness of intravenous immunoglobulin (IVIG) alone, high dose methylprednisolone (HDMP) alone and the combination of IVIG and HDMP in the treatment of childhood immune thrombocytopenic purpura (ITP). BACKGROUND:Acute ITP in children is a self-limited disease with a benign course and low ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::Folate deficiency is one of today's most common vitamin deficiencies in women. Women who consume a low level of folate during pregnancy are at risk for poor pregnancy outcomes including neural tube defects (NTD). However, other factors such as heredity, social class, maternal age, birth order, maternal diet, length of...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To describe the respiratory pathogens found in the bronchoalveolar lavage of a Puerto Rican population infected with the human immunodeficiency virus (HIV). BACKGROUND:Empirical treatment is an accepted strategy for management of HIV-related pneumonia, but it is usually recommended for countries that have kn...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::The identification of Streptococcus mutans from dental plaque samples with rapid systems, such as the RapID STR System, has not been recommended by the manufacturers. In this study, we evaluated the use of the above method for the identification of 34 human dental plaque Streptococcus mutans strains which had been ide...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::Human physiology depends on countless biochemical reactions, numerous of which are co-dependent and interrelated. The speed and level of completion of reactions usually depend on the availability of precursors and enzymes. The enzymatic activity depends on the bioavailability of micronutrient cofactors such as vitamin...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2015-03-01 00:00:00
abstract::Renal cell carcinoma is the most common cancer of the kidney and is among the tumors that are the most resistant to systemic therapy. Until recently, long term survival of this disease when it was not confined to the kidney was dismal, with the use of drugs such as interleukin-2 resulting in a 5-year survival rate of ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:A preliminary investigation to test the efficacy of intravenous propranolol in reducing the cesarean section rate in nulliparas in active labor and evaluate its effect on neonatal and maternal outcomes. METHODS:Fifty seven nulliparous patients admitted in active labor were randomly divided into two groups: a...
journal_title:Puerto Rico health sciences journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-03-01 00:00:00
abstract::This review of literature identifies different ergometers used for the assessment of the physiological and metabolic responses observed during exercise in air (treadmill, cycle ergometer, arm ergometer, bench step, swim bench, and simulated swimming) and water (tethered or stationary swimming, swimming flume, and free...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:The present study was performed to detect cancer risk of the midwifes and nurses playing central role in raising awareness in the society using Gail's model. MATERIALS AND METHODS:Sample of the present cross sectional study consists of 750 volunteer midwifes and nurses in 2016. Breast cancer risk was calcula...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the utility of the substituted judgement standard in terminally ill patients by determining agreement between patients, family proxies and physicians. BACKGROUND:Several studies have addressed the utility of substituted judgement, showing conflicting data whether surrogates are accurate predictin...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of pediatric brain tumors treated at the University Pediatric Hospital of Puerto Rico over a 6-year period and examine the demographic data and tumor histology of patients in different age groups. METHODS:A retrospective study was undertaken at the University Pediatric Hospital. We...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Pre- and postoperative evaluation of the pediatric patient with a cerebrovascular malformation can be cumbersome. This may be due to several factors, including age and ability to verbalize. Functional evaluation scales have been devised, yet application to a retrospective study, where information can be limi...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::This article examines the available data on the health status of Puerto Rican women in the United States. Statistics on reproductive health, cancer and AIDS indicate that the health status of these women is lower than that of both their U.S. and island counterparts. Usually, the health of immigrants lies somewhere bet...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::The prevalence of concomitant thyroid carcinoma with Grave's disease has been reported to range from 0 to 10%. Many controversies exist in the literature regarding the diagnostic workup and management in these types of patients. We are reporting a case of a 31 year old woman who had Graves' disease, a palpable thyroid...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract::Candida is the fourth most common cause of nosocomial bloodstream infections (BSI), being Candida albicans the most common species. This study evaluated the distribution of Candida spp isolates at a tertiary care medical center. The associated factors and outcome of patients with candidemia at the Puerto Rico Medical ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract::113 rhesus monkeys, representing 4 age classes, 3 matrilines, and immigrant adult males in a 161-member Cayo Santiago-derived troop living in a 2-acre enclosure, were sampled for levels of plasma ACTH and cortisol during a period of capture and brief cage confinement for routine veterinary examination. ACTH levels sho...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::Although injection drug use (IDU) is the major risk category for HIV infection in Puerto Rico and injection drug users start their drug injection careers very young, there is little information related to drug injection patterns of young IDUs. In this paper we report on factors found to be associated with HIV seroposi...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Advances in the understanding of chondrocytes and the synovial membrane as targets of and participants in the inflammatory process in articular joints have provided insights into the role of inflammation in cartilage and subchondral bone injury in rheumatic diseases. Reports that describe the inflammatory cellular inf...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2017-09-01 00:00:00
abstract::Diagnosing cancer using microarray analysis to study differential gene expression has been a recent focus of intense research Although several very sophisticated analysis tools have been developed with this aim in mind, it still remains a challenge to keep these methods free of parametric adjustments as well as mainta...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::The AIDS pandemic had a significant impact in Puerto Rico, especially among the heterosexual populations, in particular women. Women are one of the fastest growing risk groups with HIV/AIDS in the USA and constitute about half of the AIDS cases in the world. During the past 10 years Puerto Rico has ranked among the to...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00