HER2 Equivocal Status in Early Breast Cancer Is Not Associated with Higher Risk of Recurrence.

abstract：:We report two cases with small cell lung cancer (SCLC) receiving multicyclic dose-intensified chemotherapy (DI-CT) supported by autologous blood progenitor cell transplantation (ABPCT). Both cases were initially treated with cisplatin (CDDP), etoposide (ETP) and concurrent thoracic irradiation, however they had recurr...

journal_title：Anticancer research

authors： Fujimoto N,Ueoka H,Kiura K,Tabata M,Bessho A,Takata I,Sunami K,Hiramatsu Y,Ikeda K,Tanimoto M,Harada M

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND/AIM:MicroRNAs (miRNAs) are closely associated with a number of cellular processes, including cell development, differentiation, proliferation, carcinogenesis, and apoptosis. The aim of the present study was to elucidate the molecular mechanisms underlying the tumor suppressor activity of miRNA-203 (miR-203) ...

journal_title：Anticancer research

authors： Kim JS,Choi DW,Kim CS,Yu SK,Kim HJ,Go DS,Lee SA,Moon SM,Kim SG,Chun HS,Kim J,Kim JK,Kim DK

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND/AIM:Nodal staging is used in colorectal cancer (CRC) to determine which patients should receive adjuvant chemotherapy. The aim of this study was to evaluate the role of indocyanine green fluorescence imaging (ICG-FI) in sentinel lymph node (SLN) detection compared to the standard technique. MATERIALS AND ME...

journal_title：Anticancer research

authors： Liberale G,Vankerckhove S,Galdon MG,Larsimont D,Ahmed B,Bouazza F,Moreau M,El Nakadi I,Donckier V,Bourgeois P,R&D Group for the Clinical Application of Fluorescence Imaging at the Jules Bordet Institute.

更新日期：2016-09-01 00:00:00

abstract：:In order to improve the treatment of advanced H&N cancer we must consider to adopt new strategies as: new/better cytostatic agents; new combinations of present cytostatic agents and; potentiation of radiotherapy and cytostatic agents by biochemical modulation, which we define as potentiation of therapy by non-chemothe...

journal_title：Anticancer research

authors： Wennerberg J,Kjellén E,Lybak S,Rydell R,Pero R

更新日期：1993-11-01 00:00:00

abstract：AIM:The present study aimed to examine the survival benefit of adjuvant chemotherapy for the patients with stage IB gastric cancer according to the second English edition of the Japanese Classification of Gastric Carcinoma (2nd JCGC). PATIENTS AND METHODS:In total, 201 consecutive patients who underwent curative surge...

journal_title：Anticancer research

authors： Toyokawa T,Ohira M,Sakurai K,Kubo N,Tanaka H,Muguruma K,Hirakawa K

更新日期：2015-07-01 00:00:00

abstract：AIM:After radical prostatectomy, PSA levels that reach near zero values in less than 14 days are associated with a favourable prognosis. The aim of this analysis was to investigate whether PSA also declines to near zero values after combined tele-brachytherapy. MATERIALS AND METHODS:Forty-one patient, treated with com...

journal_title：Anticancer research

authors： Schüller P,Schäfer U,Micke O,Panke JE,Willich N

更新日期：2005-05-01 00:00:00

abstract：AIM:To assess the ability of ultrasound (US)-guided vacuum-assisted breast excision (VAE) to remove Breast Imaging Reporting and Data System (BI-RADS) ≥3 breast lesions in order to analyze US features most frequently associated with complete excision. MATERIALS AND METHODS:A total of 266 BI-RADS ≥3 lesions without mic...

journal_title：Anticancer research

authors： Perretta T,Lamacchia F,Ferrari D,Beninati E,DI Tosto F,DE Stasio V,Meucci R,DI Stefano C,Buonomo OC,Vanni G,Pistolese CA

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:18F-FDG positron emission tomography (PET) may alter therapeutic management of patients with cervical cancer because 18F-FDG-positive pelvic and para-aortic lymph nodes are associated with lower progression-free survival and vice versa. However, the accuracy of 18F-FDG PET might be impaired by a preceding ly...

journal_title：Anticancer research

authors： Reinhardt MJ,Technau-Ihling K,Altehoefer C,Vogelgesang D,Krause TM

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND/AIM:In order to develop an efficient drug-delivery system (DDS), a lipopeptide-loaded liposome that functions as a platform for the transpeptidase reaction mediated by sortase A (SrtA) was constructed and its stability, as well as cell-specific targeting were evaluated in the present study. MATERIALS AND ME...

journal_title：Anticancer research

authors： Tabata A,Ohkubo Y,Anyoji N,Hojo K,Tomoyasu T,Tatematsu Y,Ohkura K,Nagamune H

更新日期：2015-08-01 00:00:00

abstract：:Taking into account the possible regulatory influences of the beta-adrenergic system on lymphocyte proliferation as well as the proposed role of cyclic 3'-5'-adenosine monophosphate (cAMP) in the modulation of multidrug resistance (MDR) in tumour cells, we have tried to assess the status of the interactions between th...

journal_title：Anticancer research

authors： D'Amico C,Crescimanno M,Armata MG,Leonardi V,Palazzoadriano M,D'Alessandro N

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Zoledronate (Zol), an anti-osteoclastic and anticancer drug, is used to control bone metastasis in several cancer types, including non-small cell lung cancer (NSCLC). However, the mechanisms behind Zol resistance in NSCLC are unclear. MATERIALS AND METHODS:Zol-resistant cell lines were developed by repeated...

journal_title：Anticancer research

authors： Aoyagi T,Morii T,Ohtsuka K,Ohnishi H,Tajima T,Yoshiyama A,Mochizuki K,Satomi K,Ichimura S

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Breast cancer cells frequently metastasize to the skeleton and produce and secrete proteinases, such as matrix metalloproteinase-13 (MMP-13), which promote destruction of the bone matrix. However, the mechanism of MMP-13 expression induced in areas of bone metastasis is unknown. Here, the interaction between...

journal_title：Anticancer research

authors： Ibaragi S,Shimo T,Hassan NM,Isowa S,Kurio N,Mandai H,Kodama S,Sasaki A

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Serum autoantibodies (AAb) against mutated p53 protein have been detected in patients with invasive breast cancer of all stages. The present pilot study was conducted to investigate the use of p53 AAb titers in monitoring patients with recurrent breast cancer. PATIENTS AND METHODS:Sequential sera of 24 pati...

journal_title：Anticancer research

authors： Regele S,Vogl FD,Kohler T,Kreienberg R,Runnebaum IB

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIM:We investigated the effect of aspirin on colorectal cancer (CRC) risk among subgroups of women with and without risk factors for CRC. PATIENTS AND METHODS:Using data from the Women's Health Initiative, we estimated hazard ratios for CRC in association with aspirin use, with stratifications by cardiovasc...

journal_title：Anticancer research

authors： Seaton ME,Peters U,Johnson KC,Kooperberg C,Bafford A,Zubair N

更新日期：2019-09-01 00:00:00

abstract：:The expression of p53 and mdm-2 proteins was analysed in parrafin sections from 39 cases of Hodgkin's disease (HD) and compared to the presence of Epstein-Barr Virus (EBV). P53 protein was found in Hodgkin and Reed-Sternberg (HRS) cells in 12/39 cases. Mdm-2 protein was found in HRS cells in 10/39 cases. EBV-encoded E...

journal_title：Anticancer research

authors： Tzardi M,Kouvidou C,Panayiotides I,Koutsoubi K,Stefanaki K,Giannikaki E,Darivianaki K,Zois M,Eliopoulos G,Kakolyris S,Delides G,Rontogianni D,Kanavaros P

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Lung cancer cells often express vimentin. However, the function of vimentin in lung cancer cells has not been fully evaluated. MATERIALS AND METHODS:We evaluated the association between vimentin expression in resected non-small cell lung cancer (NSCLC) specimens and prognosis. Short-interfering RNA targetin...

journal_title：Anticancer research

authors： Tadokoro A,Kanaji N,Liu D,Yokomise H,Haba R,Ishii T,Takagi T,Watanabe N,Kita N,Kadowaki N,Bandoh S

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Signaling between androgen receptor (AR) and mTOR may be crucial for prostate cancer cells to endure the low androgen and suboptimal nutrient conditions produced by androgen deprivation therapy. MATERIALS AND METHODS:AR and mTOR cross-talk was examined in LNCaP cells exposed to either high or low testostero...

journal_title：Anticancer research

authors： Wu Y,Chhipa RR,Cheng J,Zhang H,Mohler JL,Ip C

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Expression of novel stem cell-associated marker human embryonic stem cell 77 (HES77) was studied in rectal neuroendocrine tumors (NETs), which comprise 10 to 15% of gastroenteropancreatic NETs, some with metastatic potential. MATERIALS AND METHODS:WHO 2010 classification was applied, and immunohistochemical...

journal_title：Anticancer research

authors： Jernman J,Hagström J,Mäenpää H,Välimäki MJ,Haapasalo H,Nilsson O,Fermér C,Haglund C,Arola J

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND/AIM:Chest radiotherapy (RT) doubles late cardiac mortality. This study aimed to evaluate the evolution of cardiac changes in speckle tracking echocardiography during a three-year follow-up. MATERIALS AND METHODS:This prospective study included 81 chemotherapy-naïve early-stage breast cancer patients who wer...

journal_title：Anticancer research

authors： Tuohinen SS,Skytta T,Huhtala H,Virtanen V,Kellokumpu-Lehtinen PL,Raatikainen P

更新日期：2019-08-01 00:00:00

abstract：:Intraosseous lipomas are rare benign primary bone tumors, with an incidence of one per thousand bone tumors. We studied eleven cases of intraosseous lipoma of the calcaneus. All the patients received radiographic examinations and MRI with T1-and T2-weighted images with Gd-DTPA enhancement. Seven patients received tumo...

journal_title：Anticancer research

authors： Hirata M,Kusuzaki K,Hirasawa Y

更新日期：2001-11-01 00:00:00

abstract：:The karyotypes and selected isoenzymes of five cell lines, HU 961b, HU 1922, HU 609, HCV-29 and HU 1703 He, were characterized. These cell lines were derived either from histologically normal human urothelial cells or from transitional cell carcinoma (TCC) of the urinary bladder. They displayed different life span in ...

journal_title：Anticancer research

authors： Debiec-Rychter M,Christensen B,Kieler J,Wang CY

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the DNA methylation status of the mitogen-activated protein kinase (MAPK) signal-inhibiting genes dual-specificity phosphatase 4 (DUSP4) and 6 (DUSP6); and serpin peptidase inhibitor A member 5 (SERPINA5) in thyroid cancer. MATERIALS AND METHODS:Using 76 papillary t...

journal_title：Anticancer research

authors： Lee EK,Chung KW,Yang SK,Park MJ,Min HS,Kim SW,Kang HS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND/AIM:Despite recent introduction of several novel agents, limited data exist regarding parameters that help predict the progression of non-metastatic castration-resistant prostate cancer (nmCRPC). The objective of this study was to identify prognostic predictors in nmCRPC patients. PATIENTS AND METHODS:This ...

journal_title：Anticancer research

authors： Miyake H,Watanabe K,Matsushita Y,Watanabe H,Tamura K,Motoyama D,Ito T,Sugiyama T,Otsuka A

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Metastatic breast cancer remains a major clinical issue despite progress achieved in recent years. Three randomised trials have demonstrated the benefit of combining bevacizumab with various taxane schedules. Herein, this study sought to investigate an alternative bevacizumab-taxane regimen as first-line tre...

journal_title：Anticancer research

authors： Kountourakis P,Doufexis D,Maliou S,Karagiannis A,Kardara E,Margari C,Sykoutri D,Tzovaras A,Ardavanis A

更新日期：2010-07-01 00:00:00

abstract：:This review describes the use of murine polyomavirus "virus-like" particles (MPyV-VLPs), free from viral genes, as vectors for gene and immune therapy and as vaccines. For large-scale MPyV-VLP manufacture, VP1 is produced in a baculovirus insect cell system, E. coli or in yeast. MPyV-VLPs bind eukaryotic DNA and intro...

journal_title：Anticancer research

authors： Tegerstedt K,Franzén AV,Andreasson K,Joneberg J,Heidari S,Ramqvist T,Dalianis T

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The influence of age on the patterns and outcomes of external beam radiotherapy for clinically localized prostate cancer patients was examined. MATERIALS AND METHODS:The Japanese Patterns of Care Study surveys were used to compare the processes and outcomes of radical external beam radiotherapy in 140 elder...

journal_title：Anticancer research

authors： Ogawa K,Nakamura K,Onishi H,Koizumi M,Sasaki T,Araya M,Miyabe Y,Otani Y,Teshima T,Japanese Patterns of Care Study Working Subgroup of Prostate Cancer.

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Perillyl alcohol (POH) elicited anticarcinogenic effects in a number of cancer models and pharmacokinetic studies in humans revealed that PA is the major circulating metabolite following POH administration. MATERIALS AND METHODS:Effects of PA or POH alone, or in combination with radiation, on human head and...

journal_title：Anticancer research

authors： Samaila D,Toy BJ,Wang RC,Elegbede JA

更新日期：2004-09-01 00:00:00

abstract：:Iceland has a total population of 300,000 inhabitants. All patients consulting for symptoms of the lower digestive tract during a four-year period (2003-2006) were subjected to a colonoscopic examination; all polyps were endoscopically removed. Out of the total 3,037 colorectal adenomas (CRAs), 308 (10.2%) were tradit...

journal_title：Anticancer research

authors： Rubio CA,Jónasson JG

更新日期：2015-09-01 00:00:00

abstract：:BK virus was isolated by Gardner et al in 1971 from the urine of an immunosuppressed patient with a kidney allograft. Antibodies to this virus are ubiquitous in the general populations worldwide, but the oncogenic capacity of BKV in humans had not been reported. The virus transformed in vitro permissive human and non-...

journal_title：Anticancer research

authors： Sekiguchi M,Miyazaki S,Fujikawa K,Shiroko Y,Asanuma K

更新日期：1996-07-01 00:00:00

abstract：CASE REPORT:This case study reports on a patient who relapsed with thymoma (mixed type) nine years after tumor resection. After four courses of rescue chemotherapy (docetaxel and cisplatinum), the patient was further diagnosed with pure red cell aplasia. It was noticed that cyclosporin A (CsA), which was administered t...

journal_title：Anticancer research

authors： Li P,Du F,Gong Z,Hu B,Chi C,Chu H,Chen J

更新日期：2017-08-01 00:00:00