Imaging of cerebral ischemic edema and neuronal death.

Abstract:

PURPOSE:In acute cerebral ischemia, the assessment of irreversible injury is crucial for treatment decisions and the patient's prognosis. There is still uncertainty how imaging can safely differentiate reversible from irreversible ischemic brain tissue in the acute phase of stroke. METHODS:We have searched PubMed and Google Scholar for experimental and clinical papers describing the pathology and pathophysiology of cerebral ischemia under controlled conditions. RESULTS:Within the first 6 h of stroke onset, ischemic cell injury is subtle and hard to recognize under the microscope. Functional impairment is obvious, but can be induced by ischemic blood flow allowing recovery with flow restoration. The critical cerebral blood flow (CBF) threshold for irreversible injury is ~15 ml/100 g × min. Below this threshold, ischemic brain tissue takes up water in case of any residual capillary flow (ionic edema). Because tissue water content is linearly related to X-ray attenuation, computed tomography (CT) can detect and measure ionic edema and, thus, determine ischemic brain infarction. In contrast, diffusion-weighted magnetic resonance imaging (DWI) detects cytotoxic edema that develops at higher thresholds of ischemic CBF and is thus highly sensitive for milder levels of brain ischemia, but not specific for irreversible brain tissue injury. CONCLUSION:CT and MRI are complimentary in the detection of ischemic stroke pathology and are valuable for treatment decisions.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

von Kummer R,Dzialowski I

doi

10.1007/s00234-017-1847-6

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

545-553

issue

6

eissn

0028-3940

issn

1432-1920

pii

10.1007/s00234-017-1847-6

journal_volume

59

pub_type

杂志文章,评审
  • Extraspinal abnormalities identified on lumbar spine CT.

    abstract::Retrospective review of 1517 lumbar CT examinations revealed extraspinal pathology in 22 (1.45%). Retroperitoneal tumors and lymphadenopathy as well as vascular, urinary tract and gynecologic abnormalities were identified. This study demonstrates the need to carefully evaluate the visualized portions of the abdomen an...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00341767

    authors: Frager DH,Elkin CM,Kansler F,Mendelsohn SL,Leeds NE

    更新日期:1986-01-01 00:00:00

  • Hyperacute infarction: a comparison of CT and MRI, including diffusion-weighted imaging.

    abstract::We compared CT and MRI obtained within the first 3 h of onset of a cerebral infarct. Echo-planar diffusion-weighted MRI delineated the infarcted areas most clearly, and subtle low-density areas on CT were consistent with those shown to be abnormal by diffusion-weighted MR. The signal changes of affected areas on fast ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340050727

    authors: Maeda M,Abe H,Yamada H,Ishii Y

    更新日期:1999-03-01 00:00:00

  • Results of a double blind study of three contrast media and technic for lumbosacral radiculography.

    abstract::The rate of side effects, the results of EMG, EEG and CSF changes after radiculography, the rates of late leptomeningeal changes and the details of the hyperosmolality following the ionic contrast media are recorded and discussed. In conclusion rules are presented for the choice of contrast medium and the examination ...

    journal_title:Neuroradiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF00345269

    authors: Hammer B

    更新日期:1978-11-24 00:00:00

  • Spinal tract pathology in AIDS: postmortem MRI correlation with neuropathology.

    abstract::Vacuolar myelopathy (VM) and tract pallor are poorly understood spinal tract abnormalities in patients with the acquired immunodeficiency syndrome (AIDS). We studied the ability of magnetic resonance imaging (MRI) to detect these changes in spinal cord specimens postmortem and whether criteria could be formulated whic...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588630

    authors: Santosh CG,Bell JE,Best JJ

    更新日期:1995-02-01 00:00:00

  • Magnetic resonance imaging and risk factors for progression of lacunar infarct lesions in Chinese patients.

    abstract:PURPOSE:The proportion of acute symptomatic lacunar infarction lesions that undergo cavitation and the factors influencing cavity formation are yet unclear, particularly in the Chinese population. Hence, we investigated changes in the diameter of acute lacunar infarction lesions and identified the risk factors for the ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-019-02303-z

    authors: Du M,Bai H,Chen J,Zeng Z,Song J,Chen S,He H,Wei H,Li T,Xiao X

    更新日期:2020-02-01 00:00:00

  • Lateralisation with magnetic resonance spectroscopic imaging in temporal lobe epilepsy: an evaluation of visual and region-of-interest analysis of metabolite concentration images.

    abstract::We carried out spectroscopic imaging (MRSI) on nine consecutive patients with temporal lobe epilepsy being assessed for epilepsy surgery, and nine neurologically healthy, age-matched volunteers. A volume of interest (VOI) was angled along the temporal horns on axial and sagittal images, and symmetrically over the temp...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340100560

    authors: Vikhoff-Baaz B,Malmgren K,Jönsson L,Starck G,Ljungberg M,Forssell-Aronsson E,Uvebrant P,Ekholm S

    更新日期:2001-09-01 00:00:00

  • C-arm cone beam computed tomography needle path overlay for image-guided procedures of the spine and pelvis.

    abstract:INTRODUCTION:The aim of this study is to report our early clinical experience using C-arm cone beam computed tomography with fluoroscopic overlay for image guidance during percutaneous needle procedures of the spine and pelvis. METHODS:Twelve consecutive patients (four female and eight male patients; mean age, 64 year...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-011-0866-y

    authors: Leschka SC,Babic D,El Shikh S,Wossmann C,Schumacher M,Taschner CA

    更新日期:2012-03-01 00:00:00

  • Does registration of serial MRI improve diagnosis of dementia?

    abstract:INTRODUCTION:We aimed to assess the value of a second MR scan in the radiological diagnosis of dementia. METHODS:One hundred twenty subjects with clinical follow-up of at least 1 year with two scans were selected from a cognitive disorders clinic. Scans were reviewed as a single first scan (method A), two unregistered...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-010-0665-x

    authors: Barnes J,Mitchell LA,Kennedy J,Bastos-Leite AJ,Barker S,Lehmann M,Nordstrom RC,Frost C,Smith JR,Garde E,Rossor MN,Fox NC

    更新日期:2010-11-01 00:00:00

  • Endovascular occlusion of direct carotid cavernous fistula with detachable balloons: usefulness of 3D angiography.

    abstract::The objective of this study is to show rotational 3D angiography findings and their usefulness in the occlusion of carotid cavernous fistulas (CCFs) using detachable balloons. Five patients with direct CCF were retrospectively reviewed for details of interventional procedures and 2D and 3D angiography findings. Prethe...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-005-1337-0

    authors: Kwon BJ,Han MH,Kang HS,Chang KH

    更新日期:2005-04-01 00:00:00

  • Accidental introduction of contrast medium into the cervical spinal cord. A case report.

    abstract::The density of metrizamide injected accidentally into the spinal cord during cervical CT myelography was measured with CT scanning and compared with a series of dilutions of metrizamide scanned with a special phantom. The test suggests that the metrizamide is diluted rapidly in the spinal canal, and in an accidental i...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00342522

    authors: Servo A,Laasonen EM

    更新日期:1985-01-01 00:00:00

  • Ill-defined focal low attenuation in the posterior internal capsule: a normal CT finding.

    abstract::Although many pathological changes in the internal capsule may lead to neurological deficits, we often encounter ill-defined focal low attenuation in the posterior limb of the internal capsule (PIC) on CT in patients with no neurological disturbance. Brain CT studies of 141 patients without neurological deficits were ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00604795

    authors: Adachi M,Yamaguchi K,Hosoya T

    更新日期:1996-02-01 00:00:00

  • Local intraarterial fibrinolytic therapy in inaccessible internal carotid occlusion.

    abstract::Two exemplary cases of upper carotid occlusion and successful local intraarterial fibrinolytic therapy are described. To achieve a positive result one has to perform a balloon occlusion of the affected internal carotid artery while applying the fibrinolytic agent. Possible time limits of instigating therapy are discus...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00339777

    authors: Zeumer H,Hündgen R,Ferbert A,Ringelstein EB

    更新日期:1984-01-01 00:00:00

  • GM-2 gangliosidosis (Sandhoff's disease): two year follow-up by MRI.

    abstract::Two children with GM-2 gangliosidosis type 0 (Sandhoff's disease) followed up by MRI at 1.5 Tesla for 1.8 years are reported. One was presymptomatic at the first MRI examination. As her neurological status deteriorated, MRI showed low signal in bilaterally, on T2-weighted images the white matter with involvement of th...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588086

    authors: Koelfen W,Freund M,Jaschke W,Koenig S,Schultze C

    更新日期:1994-01-01 00:00:00

  • Analysis of the utility of diffusion-weighted MRI and apparent diffusion coefficient values in distinguishing central nervous system toxoplasmosis from lymphoma.

    abstract:INTRODUCTION:Toxoplasmosis and lymphoma are common lesions of the central nervous system in patients with AIDS. It is often difficult to distinguish between these lesions both clinically and radiographically. Previous research has demonstrated restricted diffusion within cerebral lymphomas and bacterial abscesses. Howe...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-006-0123-y

    authors: Schroeder PC,Post MJ,Oschatz E,Stadler A,Bruce-Gregorios J,Thurnher MM

    更新日期:2006-10-01 00:00:00

  • A reappraisal of the diagnosis in cervical disc disease: the posterior longitudinal ligament perforated or not.

    abstract::Herniated nuclear material of the cervical disc often perforates the posterior longitudinal ligament. Of 22 patients who were operated on by an anterior approach, 10 were of this type (the subligamentous type of cervical disc protrusion), while in the remaining 12 patients and 15 discs the protruded disc caused no tea...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00548195

    authors: Isu T,Iwasaki Y,Miyasaka K,Abe H,Tashiro K,Ito T

    更新日期:1986-01-01 00:00:00

  • Anomalous origin of the posterior meningeal artery from the lateral medullary segment of the posterior inferior cerebellar artery.

    abstract::The authors present two cases of angiographically-confirmed anomalous origin of the posterior meningeal artery (PMA) from the lateral segment of the posterior inferior cerebellar artery (PICA) and describe briefly the probable embryogenesis of this anomaly. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00341048

    authors: Tanohata K,Maehara T,Noda M,Katoh H,Sugiyama S,Okazaki A

    更新日期:1987-01-01 00:00:00

  • Multiplanar reconstructed CT images increased depiction of intracranial hemorrhages in pediatric head trauma.

    abstract:INTRODUCTION:The benefits of multiplanar reconstructed images (MPR) of unenhanced axial head computed tomography (CT) data have not been established in trauma patients younger than 3 years old, a population in which a reliable history and physical examination may be most difficult. We retrospectively evaluated unenhanc...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-015-1584-7

    authors: Langford S,Panigrahy A,Narayanan S,Hwang M,Fitz C,Flom L,Lee VK,Zuccoli G

    更新日期:2015-12-01 00:00:00

  • Endovascular coil embolization for anterior choroidal artery aneurysms.

    abstract:INTRODUCTION:We retrospectively evaluated the ischemic complications related to the anterior choroidal artery (AChA) and clinical outcome after coiling of AChA aneurysms. METHODS:We included 37 patients (27 with subarachnoid hemorrhage, 10 without) harboring 38 AChA aneurysms (23 ruptured, 15 unruptured) who were trea...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-007-0331-0

    authors: Kim BM,Kim DI,Chung EC,Kim SY,Shin YS,Park SI,Kim DJ,Suh SH,Choi CS,Won YS

    更新日期:2008-03-01 00:00:00

  • Regional cerebral blood flow levels as measured by xenon-CT in vascular territorial low-density areas after subarachnoid hemorrhage are not always ischemic.

    abstract:INTRODUCTION:The aim of this study was to assess regional cerebral blood flow (rCBV) in areas of CT hypoattenuation appearing in the postoperative period in patients treated for aneurysmal subarachnoid hemorrhage (SAH) using xenon-enhanced CT scanning (Xe-CT). METHODS:We analyzed 15 patients (5 male and 10 female; mea...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-006-0111-2

    authors: Fainardi E,Tagliaferri MF,Compagnone C,Tanfani A,Cocciolo F,Battaglia R,Frattarelli M,Pascarella R,Targa L,Chieregato A

    更新日期:2006-09-01 00:00:00

  • [CT scan in Wilson's disease (author's transl)].

    abstract::We studied nine cases of Wilson's disease on CT scan. In all patients we found cerebral atrophy. In five patients without neurological symptoms we found no specific signs. In the four patients with neurological symptoms we found lenticular caudate nucleus or thalamic areas of hypodensity. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00395268

    authors: Merland JJ,Chiras J,Melki JP,Cassan JL

    更新日期:1978-01-01 00:00:00

  • Unilateral absence of cerebellar hemisphere: a case report.

    abstract::We describe a 38-year-old woman with absence of right cerebellar hemisphere incidentally discovered by MR imaging. No cerebellar abnormality was detected on neurological examination. Tissue probably representing dysgenetic cerebellar tissue with no corticomedullary differentiation was present, connected to the right s...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340100679

    authors: Erdogan N,Kocakoc E,Bekar D,Ozturk

    更新日期:2002-01-01 00:00:00

  • Single-energy metal artifact reduction technique for reducing metallic coil artifacts on post-interventional cerebral CT and CT angiography.

    abstract:PURPOSE:To evaluate the effects of the single-energy metal artifact reduction (SEMAR) algorithm on image quality of cerebral CT and CT angiography (CTA) for patients who underwent intracranial aneurysm coiling. METHODS:Twenty patients underwent cerebral CT and CTA using a 320-detector row CT after intracranial aneurys...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-018-2081-6

    authors: Katsura M,Sato J,Akahane M,Tajima T,Furuta T,Mori H,Abe O

    更新日期:2018-11-01 00:00:00

  • Micro-computed tomography: a new diagnostic tool in postmortem assessment of brain anatomy in small fetuses.

    abstract:PURPOSE:The aim of our study was to evaluate the postmortem micro-CT anatomy of early fetal human fetal brains, either in situ or isolated. METHODS:We studied 12 ex vivo specimens, 9 whole human fetuses (9-18 GW), and 3 isolated samples (16-26 GW). Specimens were fixed in formalin, then immersed in Lugol solution. Ima...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-019-02168-2

    authors: Lombardi S,Scola E,Ippolito D,Zambelli V,Botta G,Cuttin S,Triulzi F,Lombardi CM

    更新日期:2019-07-01 00:00:00

  • Intracranial tuberculoma: MR imaging.

    abstract::MR studies of 6 patients with intracranial tuberculoma are reviewed. All patients also underwent CT scans which showed hypo- or isodense lesions with abnormal enhancement following contrast administration. MR showed lesions with prolongation of the T1 relaxation time in every case. On the T2-weighted sequences, the si...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00344170

    authors: Salgado P,Del Brutto OH,Talamás O,Zenteno MA,Rodríguez-Carbajal J

    更新日期:1989-01-01 00:00:00

  • Patterns of skull base fracture: a three-dimensional computed tomographic study.

    abstract::Three-dimensional (3D) computed tomographic (CT) reconstructions were studied retrospectively in 14 patients with skull base fractures. Our aim was to assess the clarity of visualisation and pattern of these fractures. The reformations were obtained from 3 mm thick two-dimensional (2D) CT images. The 2D data stored on...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00600424

    authors: Ali QM,Dietrich B,Becker H

    更新日期:1994-11-01 00:00:00

  • MRA versus digital subtraction angiography in acute subarachnoid haemorrhage: a blinded multireader study of prospectively recruited patients.

    abstract::We performed a blinded multireader study comparing MR angiography (MRA) with digital subtraction angiography (DSA) in 34 prospectively recruited patients who presented with acute subarachnoid haemorrhage (SAH). Two observers independently reviewed the MRA and DSA studies some months after clinical presentation. Presen...

    journal_title:Neuroradiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s002340050892

    authors: Jäger HR,Mansmann U,Hausmann O,Partzsch U,Moseley IF,Taylor WJ

    更新日期:2000-05-01 00:00:00

  • Endovascular treatment of anterior communicating artery aneurysms using Guglielmi detachable coils.

    abstract::The aim of this study was to evaluate endovascular treatment of anterior communicating artery aneurysms using Guglielmi detachable coils GDC. To obtain long-term follow-up, we selected patients treated between October 1992 and March 1994. Among the 251 berry aneurysms treated by detachable coils at our institution, 36...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340050352

    authors: Moret J,Pierot L,Boulin A,Castaings L,Rey A

    更新日期:1996-11-01 00:00:00

  • Evaluation of Pott's disease with computed tomography.

    abstract::The CT appearance of eight cases of culture-positive spinal tuberculosis is reviewed. Three patients had single level vertebral involvement, while five others showed multilevel involvement. In seven of eight cases, paraspinal soft tissue involvement was seen. In two, the process caused neurologic symptoms by extending...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00342676

    authors: LaBerge JM,Brant-Zawadzki M

    更新日期:1984-01-01 00:00:00

  • Nasal polyps with metaplastic ossification: CT and MR imaging findings.

    abstract:INTRODUCTION:Metaplastic ossification is a rare event in nasal polyps. The purpose of this study was to review the computed tomography (CT) and magnetic resonance (MR) imaging findings of nasal polyps with metaplastic ossification. METHODS:CT (n=5) and MR (n=3) images of five patients (four men and one woman; mean age...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-010-0758-6

    authors: Kim YK,Kim HJ,Kim J,Chung SK,Kim E,Ko YH,Kim ST

    更新日期:2010-12-01 00:00:00

  • Comparison of volumetric methods for tumor measurements on two and three dimensional MRI in adult glioblastoma.

    abstract:INTRODUCTION:Change in tumor size is a frequent endpoint in cancer clinical trials, but whether change in size should be measured using volume on two-dimensional (2D) or three-dimensional (3D) images is not certain. We compared volumetric measurements on post-contrast 2D and high-resolution 3D T1-weighted MR images (T1...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-010-0789-z

    authors: Wang MY,Cheng JL,Han YH,Li YL,Dou SW,Yan FS,Shi DP

    更新日期:2011-08-01 00:00:00