Abstract:
:Two children with GM-2 gangliosidosis type 0 (Sandhoff's disease) followed up by MRI at 1.5 Tesla for 1.8 years are reported. One was presymptomatic at the first MRI examination. As her neurological status deteriorated, MRI showed low signal in bilaterally, on T2-weighted images the white matter with involvement of the optic radiations. In the second, MRI correlated well with the clinical progression of the disease, showing in the different stages involvement of thalamus and basal ganglia. There was no contrast enhancement and the grey matter remained normal.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Koelfen W,Freund M,Jaschke W,Koenig S,Schultze Cdoi
10.1007/BF00588086subject
Has Abstractpub_date
1994-01-01 00:00:00pages
152-4issue
2eissn
0028-3940issn
1432-1920journal_volume
36pub_type
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