Diabetes is associated with perforated appendicitis: evidence from a population-based study.

Abstract:

BACKGROUND:The purpose of this study was to investigate the relationship between perforated appendicitis and patient with diabetes using a population-based data set. METHODS:This study used data from the Longitudinal Health Insurance Database 2005 in Taiwan. We identified 4,806 patients hospitalized with acute appendicitis. The independent variable was whether a patient had ever received a diagnosis of diabetes before the index hospitalization. We performed a conditional logistic regression model to explore the odds ratio and its corresponding 95% confidence interval of perforated appendicitis. RESULTS:Rates of perforated appendicitis for patients with and those without diabetes were 46.2% and 28.3%, respectively. A chi-square test revealed that there was a significant difference in rates of perforated appendicitis between patients with and those without diabetes (P < .001). The conditional logistic regression model revealed that the adjusted odds ratio of perforated appendicitis for patients with diabetes was 1.35 (95% confidence interval = 1.11 to 1.65) compared with patients without diabetes. CONCLUSIONS:Our study demonstrated that a history of diabetes is an important factor with regard to the rate of perforated appendicitis.

journal_name

Am J Surg

authors

Wei PL,Lin HC,Kao LT,Chen YH,Lee CZ

doi

10.1016/j.amjsurg.2015.08.041

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

735-739

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(16)30207-0

journal_volume

212

pub_type

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