Abstract：
AIM:To develop and validate a test bolus (TB)-based quantitative model to create an individualised contrast medium injection protocol for use at coronary computed tomography angiography (CCTA) to improve patient-to-patient uniformity of intracoronary attenuation. MATERIALS AND METHODS:In the model-building phase, 175 patients who underwent CCTA using a traditional contrast medium injection protocol were recruited. A personalised injection equation was proposed according to the relationship between aortic enhancement and the haemodynamic parameters obtained from the TB. In the model-validation phase, a target aortic enhancement of 350 HU was set. Two hundred and fifteen additional CCTA examinations were performed using the proposed personalised injection model. Comparisons of inter-individual variability between the traditional and the proposed personalised injection protocol were performed. RESULTS:In the model-building phase, a high positive correlation between aortic enhancement and the haemodynamic parameters obtained from the TB was found. As a result, a personalised injection equation was determined using linear regression. In the model-validation phase, the average aortic enhancement was 350.5 HU, without significant differences from the preset level. Using the TB-based personalised injection protocol, inter-individual variability of aortic enhancement was significantly reduced (71.8 versus 38.9 HU, p<0.001) and patients who were scanned at 100 kVp had a reduction in the average contrast medium flow rate from 4.1 to 3.2 ml/s (p<0.001). CONCLUSIONS:The proposed TB-based injection protocol can achieve a desired preset and stable aortic enhancement.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Zhu X,Zhu Y,Liu W,Yang G,Su Z,Tang L,Xu Ydoi
10.1016/j.crad.2016.04.001subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1113-9issue
11eissn
0009-9260issn
1365-229Xpii
S0009-9260(16)30026-5journal_volume
71pub_type
杂志文章abstract：:The ability to deliver cells in appropriate doses to their targeted site of action is a well-known obstacle to optimising stem cell therapy. Systemic administration of cells results in pulmonary "trapping," which significantly decreases the number of available circulating cells to impact underlying disorders. Directed...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2016.01.005
更新日期：2016-04-01 00:00:00
abstract：AIM:To assess whether patients taking aspirin were more likely to experience bleeding complications after transrectal ultrasound (TRUS)-guided prostate biopsy. MATERIALS AND METHODS:Three hundred and eighty-seven patients taking aspirin who underwent prostate biopsy over a 3.5 year period and 731 patients not taking a...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2007.09.014
更新日期：2008-05-01 00:00:00
abstract：:In most of the radiotherapy centres the treatment planning is based on isodose lines. Isoeffect lines are also being drawn based on the concepts of TDFs and CREs. It was aimed in this work to find out whether the isoeffect lines based on the concepts of TDFs, CREs and the physical isodose lines are identical in all th...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(79)80072-0
更新日期：1979-05-01 00:00:00
abstract：AIMS:To investigate the clinical spectrum, cardiovascular magnetic resonance imaging (cMRI) characteristics, including T1 and extracellular volume fraction, and outcomes of Danon disease to facilitate further understanding of the phenotype of patients with Danon disease. MATERIALS AND METHODS:The study comprised six m...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2020.04.012
更新日期：2020-09-01 00:00:00
abstract：AIM:To evaluate the short-term results of percutaneous stent placement in treating stenosis in the aorta caused by non-specific aortitis (Takayasu's disease). METHOD:Five patients were treated by this method, all of whom had uncontrolled hypertension, haemodynamically significant stenosis in the aorta and a clinically...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(99)91239-4
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:To determine the effect of breathing on the detection of small dense pulmonary nodules of threshold conspicuity by spiral computed tomography (SCT). MATERIALS AND METHODS:Forty pulmonary nodules of high density were created by endobronchial deployment of 2 and 4mm diameter beads in the peripheral airways of ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(98)80170-0
更新日期：1998-07-01 00:00:00
abstract：AIM:To compare T1-weighted magnetization transfer (MT) with fluid attenuated inversion recovery (FLAIR) imaging for evaluating conspicuity and number of lesions in individuals with brain tuberculoma. MATERIALS AND METHODS:In all 28 patients with brain tuberculoma underwent MR examination using fast spin-echo (FSE) T2,...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2004.09.016
更新日期：2005-07-01 00:00:00
abstract：:The radiological appearances of seven cases of rib tuberculosis are discussed. The combination of rib destruction and an extrapleural soft tissue opacity in an Asian immigrant makes tuberculosis a highly likely diagnosis. The presence of an associated fluctuant chest wall swelling, enables a diagnosis of tuberculosis ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(80)80022-5
更新日期：1980-11-01 00:00:00
abstract：AIM:To investigate the diagnostic and differential diagnostic values of dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) in prostatic diseases, and to investigate the correlation between the parameters of SI-T curves and angiogenesis. MATERIALS AND METHODS:Twenty-one patients with proven prostatic carcin...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2007.07.023
更新日期：2008-02-01 00:00:00
abstract：:The use of computers is increasing in every field of medicine, especially radiology. Filmless radiology departments, speech recognition software, electronic request forms and teleradiology are some of the recent developments that have substantially increased the amount of time a radiologist spends in front of a comput...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2008.08.003
更新日期：2009-02-01 00:00:00
abstract：AIM:To evaluate retrospectively the diagnostic usefulness of transrectal ultrasound (TRUS)-guided targeted biopsy (TB) for transition zone (TZ) prostate cancer (PCa) in patients with prebiopsy magnetic resonance imaging (MRI). MATERIALS AND METHODS:A consecutive series of 38 patients who underwent TRUS-guided TB of TZ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2019.10.001
更新日期：2020-02-01 00:00:00
abstract：AIM:To assess the current practice of scaphoid fracture imaging (where initial scaphoid radiographs are normal) in the UK. MATERIALS AND METHODS:A survey monkey questionnaire was sent to 140 eligible NHS trusts derived from the NHS England database following exclusion of all non-acute and specialist centres. Four ques...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2019.02.016
更新日期：2019-06-01 00:00:00
abstract：AIM:To evaluate the relationship between intraoperative blood loss and juvenile nasopharyngeal angiofibroma (JNA) vascular supply and tumour stage in patients who underwent superselective external carotid artery (ECA) embolization. This series is unique in that all embolizations were performed by dedicated paediatric i...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2013.05.092
更新日期：2013-11-01 00:00:00
abstract：:Three patients with pancreatic clonorchiasis were examined with endoscopic retrograde pancreatography. On each of the three cases there was diffuse irregular dilatation of tributaries of the pancreatic duct in the pancreatic tail. The main pancreatic duct and tributaries draining into the body and head portion were no...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)80967-5
更新日期：1990-03-01 00:00:00
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journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2020.10.017
更新日期：2020-12-09 00:00:00
abstract：:PURPOSE: To determine whether it is possible to select patients with obstructive hydrocephalus, in the under 1 age group for endoscopic third ventriculocisternostomy (ETV) using pre-operative T2 weighted turbo spin echo (T2W-TSE) sagittal sequence Magnetic Resonance (MR) imaging; and to assess ventriculocisternostomy ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1053/crad.2000.0645
更新日期：2000-12-01 00:00:00
abstract：AIM:To evaluate splenic phenotype in autosomal dominant polycystic kidney disease (ADPKD) including presence of cysts and splenomegaly to determine if these are ADPKD related or represent unrelated incidental findings. MATERIALS AND METHODS:The axial/coronal T2-weighted images of ADPKD patients (n=215) and age/gender-...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2019.08.015
更新日期：2019-12-01 00:00:00
abstract：:Percutaneous high brachial aortography with a small diameter catheter (5 gauge) was used as an alternative to the translumbar approach in 45 patients in whom access via the femoral route was not considered possible. Only one serious complication occurred: the late development of a bleeding false aneurysm in a patient ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(86)80036-8
更新日期：1986-11-01 00:00:00
abstract：:Thirteen adult patients with biochemically proven congenital adrenal hyperplasia (CAH) were examined by computed tomography (CT). Six patients had never received glucocorticoid therapy. In three of those six patients, CT revealed a tumorous transformation in one of the hyperplastic adrenal glands. In the seven patient...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(86)80389-0
更新日期：1986-03-01 00:00:00
abstract：AIM:To evaluate the diagnostic performance of chemical shift magnetic resonance imaging (MRI) in distinguishing hepatocellular carcinomas (HCCs) from non-hepatocellular malignant tumours (non-HCCs) of the liver. MATERIALS AND METHODS:Patients with a diagnosis of malignant liver tumours examined at 3 T MRI were include...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2019.06.006
更新日期：2019-10-01 00:00:00
abstract：:The purpose of this paper is to define the normal and variable appearances of the sacroiliac joints and adjacent subchondral marrow on unenhanced and enhanced Magnetic Resonance Imaging (MRI). Twenty subjects were imaged with spin-echo T1-weighted (T1), fast spin-echo T2-weighted (T2), T1-weighted with fat suppression...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)83133-2
更新日期：1995-06-01 00:00:00
abstract：:The fine gauge Chiba needle was evaluated in percutaneous aspiration biopsy in 20 patients with suspected malignant lung neoplasm. Adequate aspirate can be obtained with one biopsy. A confident cytological diagnosis of malignancy was made in 19 out of 20 patients. Most of the patients were elderly. Nine patients devel...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(78)80181-0
更新日期：1978-11-01 00:00:00
abstract：:Chondromyxoid fibroma is a rare benign neoplasm of bone with a predominant incidence in the second and third decades of life. The commonest site is on either side of the knee joint. There is often endosteal sclerosis, well-defined scalloping and other benign features, although the cortex may be destroyed. It is common...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(82)80400-5
更新日期：1982-11-01 00:00:00
abstract：PURPOSE:The primary aim of this prospective pilot study was to determine if the administration of intravenous secretin prior to contrast-enhanced computed tomography (CT) improves pancreatic enhancement and pancreatic tumor conspicuity. The second aim was to determine the optimal timing for secretin administration prio...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2007.10.002
更新日期：2008-04-01 00:00:00
abstract：:The complication rate following radiofrequency catheter ablation for atrial fibrillation is low (<5%). Complications include pericardial effusion, cardiac tamponade, pulmonary vein stenosis, oesophageal ulceration or perforation, atrio-oesophageal fistula formation, stroke/transient ischaemic attack, phrenic nerve inj...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2013.08.018
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To assess three-dimensional computed tomography 'bronchoscopic' (3-DCTB) reconstruction of routine CT data as a non-invasive method of airway visualization, and compare it with fibreoptic bronchoscopy (FOB). METHODS:Fourteen datasets were acquired from 13 patients undergoing both FOB and CT examination of th...
journal_title：Clinical radiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0009-9260(97)80077-3
更新日期：1997-11-01 00:00:00
abstract：AIM:To evaluate the value of magnetic resonance (MR) diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADC) maps in the diagnosis of intraparenchymal epidermoid cysts (ECs). MATERIALS AND METHODS:Six cases of histopathologically proven intraparenchymal ECs were studied. All patients were examined w...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2008.01.008
更新日期：2008-07-01 00:00:00
abstract：:The radiographs in 10 surgically proven cases of caecal volvulus have been analysed. In the majority of cases of caecal volvulus a plain film diagnosis is suggested by the observation of the haustrated and disproportionately dilated viscus located anywhere in the abdomen. There is often evidence of small intestinal ai...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(80)80200-5
更新日期：1980-07-01 00:00:00
abstract：AIM:The purpose of this study was to determine the feasibility of echocardiogram (ECG)-gated multi-slice CT angiography (MCTA) in patients with clinical suspicion of acute venous thromboembolism (VTE), to investigate the effect of ECG-gating on cardiac motion artefacts, and to determine the diagnostic reader agreement ...
journal_title：Clinical radiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0009-9260(03)00348-9
更新日期：2003-11-01 00:00:00
abstract：:A comparative study is reported of endoscopy and the barium meal in the investigation of the oesophagus, stomach and duodenum, based on 281 endoscopies. There was total agreement between the two methods in 239 instances, including 101 normals, 80 peptic ulcers and nine cancers. In nine instances with unequivocal follo...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(75)80050-x
更新日期：1975-04-01 00:00:00
