Abstract：
AIM:To evaluate retrospectively the diagnostic usefulness of transrectal ultrasound (TRUS)-guided targeted biopsy (TB) for transition zone (TZ) prostate cancer (PCa) in patients with prebiopsy magnetic resonance imaging (MRI). MATERIALS AND METHODS:A consecutive series of 38 patients who underwent TRUS-guided TB of TZ lesions were evaluated. TB (mean core number, 2.4±0.6; range, 2-4) was performed by a single experienced radiologist under cognitive registration between prebiopsy MRI and TRUS. Tumour echogenicity on TRUS and Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2) scoring on MRI for targeted TZ lesions were assessed. The interrupted midline sign was defined as a focal lesion traversing the midline of the TZ leading to discontinuity of the midline on both MRI and TRUS. TZ PCa with a Gleason score of 7 or greater was defined as clinically significant PCa (csPCa). RESULTS:The cancer detection rate of TRUS-guided TB for TZ lesions was 78.9% (30/38) for any PCa and 42.1% (16/38) for csPCa. Echogenicity of TZ PCa on TRUS was various and half did not show low echogenicity (low, 50%; intermediate, 26.7%; and high, 23.3%). The interrupted midline sign was identified in 50% (19/38) of patients, which was highly predictive of TZ PCa (94.7%, 18/19). CONCLUSION:TRUS-guided TB under cognitive registration based on prebiopsy MRI findings is useful to detect TZ PCa. Knowledge of the sonographic features of TZ PCa may help to target TZ PCa accurately under cognitive registration.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Won SY,Cho NH,Choi YD,Park SYdoi
10.1016/j.crad.2019.10.001subject
Has Abstractpub_date
2020-02-01 00:00:00pages
157.e21-157.e27issue
2eissn
0009-9260issn
1365-229Xpii
S0009-9260(19)30598-7journal_volume
75pub_type
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更新日期：2008-07-01 00:00:00
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doi：10.1016/j.crad.2010.03.002
更新日期：2010-06-01 00:00:00
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doi：10.1016/s0009-9260(05)81774-x
更新日期：1994-03-01 00:00:00
abstract：AIMS:To test the hypothesis that the improved resolution afforded by 16-detector computed tomography (CT) would translate to better stress fracture detection when compared with skeletal scintigraphy. MATERIALS AND METHODS:Thirty-three cases of suspected stress fractures in 26 patients were investigated using skeletal ...
journal_title：Clinical radiology
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doi：10.1016/j.crad.2005.05.014
更新日期：2005-10-01 00:00:00
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doi：10.1016/j.crad.2005.08.017
更新日期：2006-03-01 00:00:00
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pub_type： 杂志文章,评审
doi：10.1016/j.crad.2015.06.093
更新日期：2015-11-01 00:00:00
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journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)80648-8
更新日期：1992-03-01 00:00:00
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journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2010.12.021
更新日期：2012-01-01 00:00:00
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journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2004.02.001
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doi：10.1016/s0009-9260(83)80386-9
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doi：10.1016/s0009-9260(98)80315-2
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doi：10.1053/crad.1999.0483
更新日期：2000-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/s0009-9260(97)80008-6
更新日期：1997-06-01 00:00:00
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journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)82661-3
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更新日期：2017-10-01 00:00:00
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journal_title：Clinical radiology
pub_type： 杂志文章
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journal_title：Clinical radiology
pub_type： 杂志文章
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