Abstract：
OBJECTIVES:To determine whether heat waves (HWs) affect exposure to drugs with anticholinergic effects (DACEs) on admission and the effect of such on length of stay (LOS) and in-hospital mortality in older adults. DESIGN:Retrospective. SETTING:Metropolitan teaching hospital. PARTICIPANTS:Individuals aged 65 and older with at least one chronic condition (n = 307) admitted to a medical ward during five consecutive HWs (≥5 consecutive days of a maximum temperature of ≥35 °C or ≥3 consecutive days of a maximum temperature of ≥40 °C) recorded between 2007 and 2009. Individuals admitted before or after each HW, matched for HW period, age, and day of the week admitted, served as controls (n = 1,114). MEASUREMENTS:Data on clinical and demographic characteristics, Charlson Comorbidity Index (CCI), total medication and DACE exposure on admission (any DACE, number of DACEs, or Anticholinergic Risk Scale (ARS) score), LOS, and in-hospital mortality were collected using electronic medical data. RESULTS:No significant differences in total medications, DACE exposure, CCI, number of daily admissions, LOS, or in-hospital mortality were observed between the HW and control groups. DACE exposure (ARS) predicted longer LOS during non-HW (β = 0.70, standard error (SE) = 0.27, P = .01) but not HW (β = 0.02, SE = 0.46, P = .96) periods. ARS did not predict mortality during non-HW (odds ratio (OR) = 1.02, SE = 0.12, P = .87) or HW (OR = 1.21, SE = 0.23, P = .31) periods. CONCLUSION:The effect of DACE exposure on LOS, but not mortality, is different between HW and non-HW periods in older hospitalized adults. This should be considered when assessing the effect of DACEs in pharmacoepidemiological studies.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Mangoni AA,Kim S,Hakendorf P,Mayner L,Woodman RJdoi
10.1111/jgs.14100subject
Has Abstractpub_date
2016-05-01 00:00:00pages
1091-6issue
5eissn
0002-8614issn
1532-5415journal_volume
64pub_type
杂志文章abstract：:A medical examiner's series of 71 elderly patients with fatal internal cerebral injuries demonstrated age differences with respect to the type of cerebral lesion and the causal incident. The elderly showed relatively fewer severe cerebral contusions than did a young group, but a higher incidence of subdural and intrap...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1978.tb03332.x
更新日期：1978-11-01 00:00:00
abstract：OBJECTIVES:To compare the efficacy and safety of ertapenem, 1 g once a day, with ceftriaxone, 1 g once a day, for treatment of the subgroup of patients aged 65 and older with community-acquired pneumonia (CAP) requiring parenteral therapy. DESIGN:Combined data from patients aged 65 and older in two randomized, double-...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1046/j.1532-5415.2003.51507.x
更新日期：2003-11-01 00:00:00
abstract：:In this paper, we present the consensus statement from a national conference on research priorities and methodologies for studying geriatric evaluation and management (GEM) programs. These conclusions, discussion points, and recommendations resulted from discussions of plenary papers, working group deliberations, and ...
journal_title：Journal of the American Geriatrics Society
pub_type： 共识发展会议,杂志文章,评审
doi：10.1111/j.1532-5415.1991.tb05936.x
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVES:To estimate the prevalence of diagnosed traumatic brain injury (TBI) in individuals hospitalized with hip fracture and examine its association with all-cause mortality. DESIGN:Nested cohort study. SETTING:National sample of Medicare beneficiaries from 2006 to 2010. PARTICIPANTS:Beneficiaries aged 65 and o...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15661
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To determine whether hospital costs are higher in patients with lower functional status at admission, defined as dependence in one or more activities of daily living (ADLs), after adjustment for Medicare Diagnosis-Related Group (DRG) payments. DESIGN:Prospective study. SETTING:General medical service at a ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2003.51556.x
更新日期：2003-12-01 00:00:00
abstract：:Ninety-three consecutive outpatients receiving tricyclic antidepressants for at least one month were asked about medication side effects, including excessive appetite and craving for sweets. Prevalence of these side effects and their relationship (Pearson r) to type of medication, dosage, patient characteristics, diag...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1985.tb01777.x
更新日期：1985-10-01 00:00:00
abstract：OBJECTIVES:To identify patient factors that influence physicians' decisions to recommend screening mammograms for older women. DESIGN:A cross-sectional survey including clinical case vignettes. PARTICIPANTS:Random sample of Massachusetts internists, obstetrician/gynecologists, family/general practice physicians, and ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1996.tb01371.x
更新日期：1996-10-01 00:00:00
abstract：OBJECTIVES:To characterize a comprehensive outline of the oral microflora related to pneumonia in older adults. DESIGN:Prospective and retrospective longitudinal study. SETTING:Community. PARTICIPANTS:Long-term hospitalized patients and people in nursing homes (343 subjects, aged > or =65). MEASUREMENTS:Subjects we...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02867.x
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:To develop a prediction model for kidney transplantation (KT) outcomes specific to older adults with end-stage renal disease (ESRD) and to use this model to estimate the number of excellent older KT candidates who lack access to KT. DESIGN:Secondary analysis of data collected by the United Network for Organ...
journal_title：Journal of the American Geriatrics Society
pub_type： 社论,多中心研究
doi：10.1111/j.1532-5415.2011.03652.x
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:To describe factors associated with provider-ordered influenza testing in hospitalized older adults. DESIGN:Information on participant demographics, symptoms, and provider-ordered influenza testing were collected by questionnaire and chart review. We conducted prospective laboratory-based surveillance using...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15298
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVES:The ability of older people to estimate their own memory, often referred to as "metamemory," has been evaluated in previous studies with conflicting reports regarding accuracy. Some studies have suggested that an older person's metamemory is mostly accurate, whereas others have demonstrated little relationsh...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2000.tb02634.x
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVES:To determine whether sex differences in large-artery stiffness contribute to the greater prevalence of systolic hypertension in elderly women than in elderly men. DESIGN:During a single visit arterial stiffness was assessed in the unmedicated state using four parameters. PARTICIPANTS:Three hundred seventy-...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52107.x
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:To test the utility of a memory-encoding strategy for improving prospective memory (PM), the ability to remember to execute future goals (e.g., remembering to take medications), which plays an important role in independent living in healthy older adults and those with very mild Alzheimer's disease (AD). DES...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,随机对照试验
doi：10.1111/jgs.14134
更新日期：2016-06-01 00:00:00
abstract：:Since 2012, the American Geriatrics Society (AGS) has also been collaborating with the American Board of Internal Medicine (ABIM) Foundation, joining its "Choosing Wisely" campaign on two separate lists of Five Things Healthcare Providers and Patients Should Question. The campaign is designed to engage healthcare orga...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/jgs.12770
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:To compare the risk of congestive heart failure (CHF) in elderly individuals treated with any peripheral alpha-1 antagonist for hypertension with any thiazide, test whether the risk persists in subjects without cardiovascular disease (CVD) at baseline, and examine CHF risk in normotensive men with prostatism...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52456.x
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVES:To determine the relationship between prealbumin, nutrient intake, and indicators of inflammation for recuperative and rehabilitative care patients. DESIGN:Prospective cohort. SETTING:Recuperative Care Unit within a Veterans Administration Nursing Home Care Unit. PARTICIPANTS:One hundred eleven men (100 w...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2008.01789.x
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVES:To describe the prevalence of self reported sleep disturbances in older men and women and to describe their relationships with health status and cardiovascular disease (CVD). DESIGN:Cross-sectional study of sleep disturbance, CVD, general health, psychosocial factors, physical function, and use of psychotro...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1997.tb00970.x
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVES:To determine whether cognitive test scores and cognitive decline predict incidence of first diagnosed stroke. DESIGN:Stroke-free Health and Retirement Study participants were followed on average 7.6 years for self- or proxy-reported first stroke (1,483 events). Predictors included baseline performance on a ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2008.02132.x
更新日期：2009-03-01 00:00:00
abstract：:The Schulich School of Medicine, University of Western Ontario, Canada, has created a mandatory clerkship in Elder Care that consists of small group seminars, clinical experiences, and an Elder Care manual. This article describes the use of a paper-based log to track students' clinical encounters to determine whether ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2007.01206.x
更新日期：2007-07-01 00:00:00
abstract：:As the complexity, prevalence and visibility of ethical dilemmas in medical care of the elderly have grown, hospitals and nursing homes have attempted to develop mechanisms for responding to these difficult ethical issues. While it is known that many hospitals rely on education and advice provided by an ethics committ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1988.tb01786.x
更新日期：1988-02-01 00:00:00
abstract：:Logical bases (five of which are outlined) underlie action in nutrition and aging. First, nutrition, health, and aging form an integral triad affecting all. This basis has been applied to the conceptualization of the Nutrition Program for Older Americans (NPOA). Second, in North America, malnutrition is a sequitur of ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1978.tb01958.x
更新日期：1978-05-01 00:00:00
abstract：OBJECTIVES:To determine whether body mass index (BMI) is independently associated with cognitive function in postmenopausal women and the relationship between body fat distribution as estimated by waist-hip ratio (WHR). DESIGN:Cross-sectional data analysis. SETTING:Baseline data from the Women's Health Initiative (WH...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02969.x
更新日期：2010-08-01 00:00:00
abstract：:Contrary to earlier findings, elderly patients are not at significantly greater risk of perioperative morbidity or mortality than younger patients simply because of advanced age. Increased risk, when present, is attributable to pathologic changes that are not uniformly seen in all geriatric patients. Most perioperativ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1983.tb04606.x
更新日期：1983-10-01 00:00:00
abstract：:The objectives of this study were to review the diagnostic, International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM), diagnosis related groups (DRGs), and common procedural terminology (CPT) coding and reimbursement issues (including Medicare Part B reimbursement for physicians) encounte...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1046/j.1532-5415.2002.50519.x
更新日期：2002-11-01 00:00:00
abstract：:A prospective study was carried out to determine which social, functional, or medical factors influenced the decision to admit or not to admit aged people to a general hospital in Israel. The study also focused on characteristics of patients admitted to the geriatric ward of the medical division as distinct from those...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1982.tb05060.x
更新日期：1982-10-01 00:00:00
abstract：:Because of adverse publicity regarding increased risk of endometrial cancer in women receiving estrogen therapy, a 2-year prospective study was conducted in 1976 to determine the incidence of endometrial cancer in postmenopausal women. A retrospective study for the year 1975 was also added. A postmenopausal survey c...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb01673.x
更新日期：1979-09-01 00:00:00
abstract：OBJECTIVES:To determine the effect of body mass index (BMI) at old age and at age 50 on short-term survival among persons age 65 and older. DESIGN:Cross-sectional, using the 4,791 respondents to the community interview of the 1994 National Long Term Care Survey (NLTCS). SETTING:United States of America. PARTICIPANTS...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.49259.x
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVES:To ascertain the association between self-report of low mood and unobtrusively measured behaviors (walking speed, time out of residence, frequency of room transitions, and computer use) in community-dwelling older adults using novel monitoring technologies. DESIGN:Longitudinal cohort study of older adults w...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12744
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVES:To determine whether the ability to walk 400 m could be predicted from self-reported walking habits and abilities in older adults and to develop an accurate self-report measure appropriate for observational trials of mobility when functional measures are impractical to collect. DESIGN:Cross-sectional. SETT...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52571.x
更新日期：2004-12-01 00:00:00
abstract：:The relation of serum albumin concentration to age was assessed in a series of hospitalized medical patients. Those with disease states (e.g., dysproteinemia, renal insufficiency, hepatic dysfunction, malnutrition) potentially associated with abnormal serum albumin levels were excluded, leaving a study population of 1...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb01715.x
更新日期：1979-01-01 00:00:00
