Abstract:
OBJECTIVES:To determine the relationship between prealbumin, nutrient intake, and indicators of inflammation for recuperative and rehabilitative care patients. DESIGN:Prospective cohort. SETTING:Recuperative Care Unit within a Veterans Administration Nursing Home Care Unit. PARTICIPANTS:One hundred eleven men (100 white; mean age 80, range 64-93). MEASUREMENTS:Prealbumin and seven markers of inflammation (C-reactive protein (CRP), tumor necrosis factor, and interleukin-6 (IL-6) and their soluble receptors) were measured at admission and discharge (median length of stay 23 days, interquartile range 15-40 days). Detailed calorie counts were performed daily, and intake was expressed as a percentage of estimated requirements for protein (1.5 g/kg body weight per day) and energy (Harris-Benedict equation). The study objective was examined using least-squares regression analysis. RESULTS:Discharge prealbumin and the change in prealbumin were positively correlated with protein and energy intake and inversely correlated with markers of inflammation, particularly CRP and IL-6. When all covariates were included in a multivariable regression analysis, the markers of inflammation predominantly accounted for the variance in prealbumin change (56%), whereas discharge protein intake accounted for 6%. CONCLUSION:For older recuperative care patients, prealbumin and its change during hospitalization are positively associated with protein intake, but inflammation or changes in inflammation appear to exert a much more-powerful influence on prealbumin concentration. Given the potential confounding effects of inflammation, monitoring the change in prealbumin is not an adequate substitute for a more-detailed nutritional assessment in this population.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Dennis RA,Johnson LE,Roberson PK,Heif M,Bopp MM,Cook J,Sullivan DHdoi
10.1111/j.1532-5415.2008.01789.xsubject
Has Abstractpub_date
2008-07-01 00:00:00pages
1270-5issue
7eissn
0002-8614issn
1532-5415pii
JGS1789journal_volume
56pub_type
杂志文章abstract::Familial achalasia most often has been recorded in siblings, and only rarely (twice previously) in a parent and offspring. This report concerns a third case of achalasia in a parent and offspring (mother and son). Clinical and radiographic features of the esophageal achalasia are presented. The possibility that geneti...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb01741.x
更新日期:1979-11-01 00:00:00
abstract:OBJECTIVES:To report use of breast cancer treatment (surgery, radiation, and chemotherapy) by patients with Alzheimer's disease (AD). DESIGN:Retrospective cohort study. SETTING:Surveillance, Epidemiology, and End Results (SEER) is a population-based cancer registry covering 14% of the U.S. population. PARTICIPANTS:F...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.00467.x
更新日期:2005-11-01 00:00:00
abstract::The initial assessments of cognitive, psychologic, and behavioral functioning of 17 adults enrolled in a day care program for victims of Alzheimer's disease are described. These evaluations by the staff, the patients themselves, and their primary caregivers made use of standardized quantitative measures, thus permitti...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1983.tb03398.x
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVES:To compare reports about care experiences of individuals who died within 1 year of survey with reports of those who did not. DESIGN:Medicare Advantage (MA) Consumer Assessment of Healthcare Providers and Systems (CAHPS) surveys asked about care experiences. Survey completion dates were linked to Social Secu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.12121
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To determine whether genetic variants in the ciliary neurotrophic factor (CNTF) gene are associated with muscle strength in older women. DESIGN:Cross-sectional analysis of baseline data from the Women's Health and Aging Studies I (1992) and II (1994), complementary population-based studies. SETTING:Twelve ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00693.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of exercise and amino acid supplementation in enhancing muscle mass and strength in community-dwelling elderly sarcopenic women. DESIGN:Randomized controlled trial. SETTING:Urban community in Tokyo, Japan. PARTICIPANTS:One hundred fifty-five women aged 75 and older were defin...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2011.03776.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To assess colonization and infection with methicillin-resistant Staphylococcus aureus (MRSA), high-level gentamicin-resistant enterococci (R-ENT) and gentamicin and/or ceftriaxone-resistant Gram-negative bacilli (R-GNB) and the factors that are associated with colonization and infection with these organisms. ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1994.tb06210.x
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVES:To investigate the association between different types of physical activity behavior and incident mobility limitation in older men and women and to examine whether muscle parameters mediate these associations. DESIGN:Cohort study with 4.5-year follow-up. SETTING:Metropolitan areas surrounding Pittsburgh, P...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2005.53257.x
更新日期:2005-05-01 00:00:00
abstract::Optimizing the management of antibiotic resistance is an important strategy in improving outcomes for infectious diseases in older persons. Strategies that manage antibiotic resistance must take into account all clinical settings, because resistant pathogens previously seen only in acute care facilities are becoming i...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1046/j.1532-5415.50.7s.5.x
更新日期:2002-07-01 00:00:00
abstract:CONTEXT:Racial differences in receipt of cancer prevention services may be related to poorer outcomes for minorities. Understanding reasons for such differences could help target appropriate interventions. OBJECTIVES:To determine if racial differences exist in the use of cancer prevention services among older blacks a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb04746.x
更新日期:2000-07-01 00:00:00
abstract::Innovative methods are needed to incorporate effective geriatric education into internal medicine residency programs. The purpose of this report is to describe the development and use of clinical decision-support (CDS) tools to facilitate geriatric education and improve the care delivered to older adults in an academi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.03960.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:To determine whether classic muscle function tests and jumping mechanography (JM) are related to tongue strength. DESIGN:Cross-sectional. SETTING:Community. PARTICIPANTS:Ninety-seven community-dwelling individuals aged 70 and older (49 female, 48 male, mean age 80.7, range 70-95) with and without identifi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12124
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To examine differences in a proxy measure of muscle quality across the adult life span and explore potential mechanisms of muscle quality change through identification of cross-sectional correlates of muscle quality. DESIGN:Cross-sectional study. SETTING:Baltimore Longitudinal Study of Aging. PARTICIPANTS...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12653
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:To evaluate whether levels of cognitive reserve (CR), as measured using the Wechsler Adult Intelligence Scale (WAIS)-III vocabulary test, moderated longitudinal associations between cognitive functions and decline in gait speed in a community-based cohort of older adults without dementia, specifically, wheth...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.04193.x
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:To evaluate and summarize the evidence of muscle weakness as a risk factor for falls in older adults. DESIGN:Random-effects meta-analysis. SETTING:English-language studies indexed in MEDLINE and CINAHL (1985-2002) under the key words aged and accidental falls and risk factors; bibliographies of retrieved p...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1532-5415.2004.52310.x
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:To examine the association between hospitalization, critical illness, and infection occurring during middle- and late-life and structural brain abnormalities in older adults. DESIGN:Prospective cohort study. SETTING:Atherosclerosis Risk in Communities (ARIC) Study. PARTICIPANTS:A community sample of adult...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15470
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:To determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus. DESIGN:Controlled clinical trial. SETTING:Primary care clinics of the Durham Veterans Affairs (VA) Medical Center betwe...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2012.04119.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:To determine the effect of four vitamin D supplement doses on falls risk in elderly nursing home residents. DESIGN:Secondary data analysis of a previously conducted randomized clinical trial. SETTING:Seven hundred twenty-five-bed long-term care facility. PARTICIPANTS:One hundred twenty-four nursing home r...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2007.01048.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:To determine the relationship between frailty and overall and cardiovascular mortality. DESIGN:Longitudinal mortality analysis. SETTING:National Health and Nutrition Examination Survey (NHANES) 1999-2004. PARTICIPANTS:Community-dwelling older adults aged 60 and older (N = 4,984; mean age 71.1 ± 0.19, 56% ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15220
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:To determine how poor sleep affects the health of older ethnic minorities. DESIGN:Cross-sectional study involving a population-based survey. SETTING:Hispanic Established Population for the Epidemiologic Study of the Elderly (H-EPESE) survey conducted in the southwestern United States. PARTICIPANTS:Two tho...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.04144.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:To investigate whether health-related quality-of-life (HRQoL) scores in a primary care population can be used as a predictor of future hospital utilization and mortality. DESIGN:Prospective cohort study measuring Short Form 12 (SF-12) scores obtained using a mailed survey. SF-12 scores, age, and a comorbidi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00681.x
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:To describe the pattern and factors associated with daily medication use in nursing home (NH) residents with advanced dementia. DESIGN:Prospective cohort study. SETTING:Twenty-two Boston-area NHs. PARTICIPANTS:NH residents with advanced dementia (N=323). MEASUREMENTS:Data from residents' records were use...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02819.x
更新日期:2010-05-01 00:00:00
abstract:UNLABELLED:Geriatric assessment units have improved pharmacotherapy for their patients by decreasing the number of medications prescribed. The Senior Care Study, a randomized controlled trial, compared a multidisciplinary-team approach to patient care to the standard medical practice of the institution. As a part of th...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1990.tb01369.x
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVES:To describe the time to first acute care use (e.g., emergency department (ED) use without hospitalization or rehospitalization) for older adults discharged to home after receiving postacute care in skilled nursing facilities (SNFs); to identify predictors of first acute care use. DESIGN:Retrospective cohort...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12602
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To examine concerns that vulnerable populations, such as depressed or cognitively impaired beneficiaries would have challenges accessing Part D coverage. DESIGN:Logistic regression analysis was used to assess whether elderly Medicare beneficiaries with depression or cognitive impairment differentially plann...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02348.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVES:To determine the extent to which disease-related symptoms and impairments, which constitute measures of disease severity or targets of therapy, account for the associations between chronic diseases and universal health outcomes. DESIGN:Cross-sectional. SETTING:The Cardiovascular Health Study (CHS) and the ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03576.x
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:To identify factors that influence the breast cancer treatment decisions of women aged 80 and older. DESIGN:Medical record review. SETTING:One academic primary care clinic and two community health centers in Boston. PARTICIPANTS:Sixty-five women aged 80 and older diagnosed with breast cancer between 1994 ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03820.x
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:Heart failure is a major health care burden among older adults, but information on recent trends has not been available. We compare rates, sociodemographic characteristics, and discharge outcomes of the initial hospitalization for heart failure in the Medicare populations of 1986 and 1993. DESIGN:Informatio...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1997.tb00939.x
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVES:To determine the distribution of influenza vaccine coverage in the United States in 2008. DESIGN:Cross-sectional analysis. SETTING:The 2008 Behavioral Risk Factor Surveillance Survey, which employs random-digit dialing to interview noninstitutionalized adults in the United States and territories. PARTICIP...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02904.x
更新日期:2010-07-01 00:00:00
abstract::By 2050, the European population of 720 million will include 187 million (one quarter) octogenarians. Although living longer is a true privilege, care for the graying population suffering from chronic and disabling diseases will raise enormous challenges to healthcare systems and geriatric education. Are European coun...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.01788.x
更新日期:2008-08-01 00:00:00