Abstract:
:Taurine (2-aminoethanesulfonic acid) is a sulfur-containing organic acid, which has various physiological functions, including membrane stabilization, cell-volume regulation, mitochondrial protein translocation, anti-oxidative activity, neuroprotection against neurotoxicity and modulation of intracellular calcium levels. Taurine also activates GABAA receptors and glycine receptors. Mammalian fetuses and infants are dependent on taurine delivered from their mothers via either the placenta or their mother's milk. Taurine is a molecule that links mother-fetus or mother-infant bonding.This review describes the functions of taurine and the mechanisms of action of taurine in fetal and brain development. Taurine is involved in regulating the proliferation of neural progenitors, migration of newly-generated neurons, and the synapse formation of neurons after migration during fetal and neonatal development. In this review, we also discuss the environmental factors that might influence the functional roles of taurine in neural development.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Tochitani Sdoi
10.1007/978-94-024-1079-2_2subject
Has Abstractpub_date
2017-01-01 00:00:00pages
17-25eissn
0065-2598issn
2214-8019journal_volume
975 Pt 1pub_type
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