Abstract：
:Loop diuretics take the lead in the treatment of patients with symptomatic heart failure. Torasemide is the most effective and safe loop diuretic with the optimal pharmacokinetic profile, the additional properties associated with simultaneous blockade of the renin-angiotensin-aldosterone system and with the antiadrenergic effects of the drug, its positive impact on myocardial fibrosis and minimal severe potential negative effects. Sustained-release torasemide provides a more comfortable removal of excess liquid and does not deteriorate quality of life. :Петлевые диуретики занимают ведущее место в лечении больных с симптоматической сердечной недостаточностью (СН). Торасемид - наиболее эффективный и безопасный петлевой диуретик с оптимальным фармакокинетическим профилем, дополнительными свойствами, связанными с одновременной блокадой ренин-ангиотензин-альдостероновой системы и антиадренергическими эффектами препарата, положительным влиянием на миокардиальный фиброз и минимально выраженными потенциально негативными эффектами. Форма торасемида с замедленным высвобождением обеспечивает более комфортное выведение излишков жидкости и не ухудшает качество жизни пациентов.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Kurlykina NV,Seredenina EM,Orlova YAdoi
10.17116/terarkh2017899115-119subject
Has Abstractpub_date
2017-01-01 00:00:00pages
115-119issue
9eissn
0040-3660issn
2309-5342journal_volume
89pub_type
杂志文章,评审abstract：:Uncontrolled hypercoagulation and inflammation (thromboinflammation), which are both independent and closely related and amplifying each other pathological processes, form the basis for pathogenesis of a wide range of diseases and complications, including immuno-inflammatory (autoimmune) rheumatic diseases, with the d...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2020.05.000697
更新日期：2020-06-05 00:00:00
abstract：AIM:To study the prevalence of metabolic syndrome (MS) and its components in a 25-45-year-old Novosibirsk population. SUBJECTS AND METHODS:The Novosibirsk Research Institute of Internal and Preventive Medicine conducted a cross-sectional population-based survey in one of the typical districts of Novosibirsk in 2013-20...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh2016881051-56
更新日期：2016-01-01 00:00:00
abstract：AIM:To evaluate effect of hemodialysis on functional state of platelet-vascular and red cell components of hemostasis in patients suffering from severe hemorrhagic fever with renal syndrome (SHFRS). MATERIALS AND METHODS:Parameters of platelet-vascular and red cell hemostasis were studied in 51 patients with SHFRS who...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：AIM:To analyse lethal outcomes in patients with newly-diagnosed respiratory tuberculosis comorbid with HIV-infection depending on initial count of CD4+ lymphocytes. MATERIAL AND METHODS:Of 304 HIV patients with newly-diagnosed tuberculosis treated in Moscow Tubercusis Hospital N 7 in 2006-2010, 40 (13.2%) patients die...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：AIM:To investigate the effect of acarbose, intestinal alpha-glucosidase inhibitor, on lipid metabolism in patients with non-insulin-dependent diabetes mellitus (NIDDM). MATERIAL AND METHODS:Glucobai was given for 6 months in a dose 300 mg/day to 63 NIDDM patients aged 40-69 years. The examination covered indices of gl...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Enteropathies (EP) are the common name for pathological (inflammatory, hemorrhagic, erosive-ulcerative, and atrophic) changes in the small bowel. The paper describes the nosological entities of EP and the significance of laboratory and instrumental methods used for their diagnosis. It outlines the principles of etiotr...
journal_title：Terapevticheskii arkhiv
pub_type： 社论
doi：
更新日期：2014-01-01 00:00:00
abstract：AIM:To evaluate the efficacy of the enterokinetic prucalopride (resolor) in patients with chronic constipation. SUBJECTS:The effect of treatment with prucalopride (resolor) in 109 patients with chronic constipation was analyzed. RESULTS:The effect was noted in 82% of the patients; 61 patients were fully satisfied wit...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Cytomegalovirus (CMV) is one of the common pathogens of opportunistic infections in patients with inflammatory bowel diseases. When the patients are treated with immunosuppressants that make them more susceptible to CMV, the course of ulcerative colitis (UC) becomes considerably worse. Antiviral therapy sometimes can ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：AIM:To study effects of two hypotensive drugs--normodipin and spirapril--on intravascular activity of platelets in patients with metabolic syndrome (MS). MATERIAL AND METHODS:Normodipin was given to 25 patients with MS for 3 months, spirapril--to 20 patients for 3 months. The effect was evaluated by changes in lipid p...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:The phasic structure of heart activity was explored in 50 patients suffering from symptomatic arterial hypertensions before and after the operative treatment with the aid of impulse Doppler echocardiography. Of these, 28 patients had renovascular hypertension (RVH), 16 primary aldosteronism (PA), and 6 pheochromocytom...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Liver is frequently involved in the pathological process. Wide range of clinical manifestations can be seen: from asymptomatic lesion with normal liver function tests to cirrhosis with portal hypertension. Biopsy plays the key role in diagnosis of...
journal_title：Terapevticheskii arkhiv
pub_type： 社论
doi：10.26442/00403660.2019.04.000179
更新日期：2019-05-15 00:00:00
abstract：:The state of the renin-angiotensin system (RAS) was studied in 102 patients with chronic glomerulonephritis with the nephrotic syndrome (NS) with relation to a phase of the edematous syndrome and sodium balance. Heterogeneity of patients with NS was shown with regard to RAS activity and the circulating blood volume in...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The authors have analyzed their experience in the diagnosis and treatment of 32 patients with broncholiths-induced obturation of the segmentary and lobar bronchi with subsequent prolonged recurring inflammatory, cirrhotic or suppurative bronchopulmonary processes farther to a site of bronchial obstruction. 37% of the ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：AIM:Epidemiological assessment of prevalence of blood hypertension (BH) in pregnant women. MATERIALS AND METHODS:Blood pressure and urinary protein were measured in 5160 gravidae observed in female consultations in 4 cities of Russia. RESULTS:BH was found in 1042(20.2%) examinees. Chronic BH was diagnosed in 306 pati...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：AIM:To study the incidence, pattern, and predictive factors of concurrent kidney and liver dysfunctions in patients with decompensated heart failure (HF). SUBJECTS AND METHODS:The kidney and liver function indicators were estimated in 322 patients aged 69.5±10.6 years with decompensated HF (hypertension in 87%, myocar...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh201688640-44
更新日期：2016-01-01 00:00:00
abstract：:Ditec effects on clinicofunctional status were investigated in 15 patients with mild and moderate atopic bronchial asthma (ABA) aged 20-50 (5 males and 10 females). A single ditec dose had a broncholytic effect along the entire bronchial tree and reduced sensitivity to acetylcholine. Magnesium sulfate (a single dose 3...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：AIM:Assessment of NO-synthase (NOS) activity in bronchial asthma (BA) basing on cytochemical identification and quantitation of NADPN-diaphorase. MATERIALS AND METHODS:Operative samples from 12 BA patients and biopsies from 8 patients free of bronchial inflammation or obstruction. Experimental data on control and BA r...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:A clinical-morphological study of bronchobiopsies from 78 patients with endoscopic picture of atrophic endobronchitis was carried out. Two forms of morphogenesis of chronic atrophic process in the bronchial mucosa are distinguished: primary dystrophic and primary inflammatory. Primary dystrophic bronchopathy is a clin...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The influence of the preliminary fat intake on the rate of contrast capsules administered with semolina porridge and morning breakfast evacuation from the gastric stump and small intestine was studied in 39 patients with gastric resection according to Billroth II by means of the x-ray method suggested for quantitation...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The most important condition for effective prophylactic medical examination is early detection of diseases. The efficacy of prophylactic medical examination of rheumatic fever patients rises considerably under the conditions of stage-by-stage therapy. Another important condition for early detection and diagnosis is ra...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：AIM:To evaluate efficiency of estrogen-gestagen treatment for protection of the ovaries during polychemotherapy. MATERIALS AND METHODS:Ultrasonography of the pelvic organs, radioimmunoassay of LH, FSH, prolactin, E2, testosterone were performed in 95 women of child-bearing age with different stages of Hodgkin's diseas...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The clinical and morphological data were studied and compared in 84 patients with Flexner's dysentery and 40 with Sonne dysentery. It is established that more pronounced and lingering colitic syndrome typical of Flexner's dysentery is related to more lasting persistence of causative agents in the superficial epitheliu...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：AIM:To study left ventricular structural and functional changes in patients with chronic obstructive pulmonary disease (COPD) and chronic cor pulmonale (CCP) at different stages of a cardiac remodeling process. SUBJECTS AND METHODS:Echocardiography was used to examine 98 patients with COPD complicated by the developme...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Some indices of pancreatic endocrine function were studied over time in patients with acute dysentery. The plasma levels of insulin, C-peptide, glucagon, and gastrin were determined by a radioimmunoassay. 35 patients and 30 healthy controls were examined. Clinical signs of the affection of the pancreas in the patients...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:28 patients treated by programmed hemodialysis (PH) were followed up from 1985 to 1991. All the patients were over 60 years old. 16 patients died within month 1-60 since PH initiation. Overall PH duration for the whole group reached 24.6 +/- 3.58 months. Pretreatment urea and creatinine in plasma of senile patients we...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:As many as 283 drivers with a history of acute myocardial infarction were examined. In the long-term postinfarction period, the number of the able-bodied accounted for 22.8%, the number of persons with restricted work fitness was 43.3%, that of the disabled amounted to 33.9%. It should be noted that about 60% of the a...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Sedacorone (amiodarone) was given to 70 outpatients with coronary heart disease for 1.5-2 years to prevent paroxysms of cardiac arrhythmia after recovery of sinus rhythm. Sedacorone was administered initially in the dose 600 mg/day for 10-12 days, then the dose lowering was adjusted to the tolerance, heart rate and EC...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The efficacy and tolerability of high-dose neurotrophic drug cerebrolysin was studied in 20 patients with vascular dementia diagnosed by criteria NINDS-AIREN and DSM-IV. The drug was well tolerated, affected positively cognitive function, especially neurodynamic processes. EEG featured after treatment intensification ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：AIM:The aim of the study is to determine the prevalence of AO in the population and to assess the association with socioeconomic factors according to the data of the ESSE-RF study (Epidemiology of Cardiovascular diseases in the Regions of the Russian Federation). MATERIALS AND METHODS:The object of the study is a rand...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh2018901014-22
更新日期：2018-11-22 00:00:00
abstract：:Twenty patients suffering from severe systemic lupus erythematosus (SLE) underwent 52 sessions of splenoperfusion (SP) by means of extracorporeal perfusion of the patient's blood through isolated porcine spleen. It got prepared directly before the perfusion. The organ was obtained from a healthy animal in sterile cond...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
