Abstract:
AIM:To study the prevalence of metabolic syndrome (MS) and its components in a 25-45-year-old Novosibirsk population. SUBJECTS AND METHODS:The Novosibirsk Research Institute of Internal and Preventive Medicine conducted a cross-sectional population-based survey in one of the typical districts of Novosibirsk in 2013-2015. The survey covered 346 men and 408 women. The criteria of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP-ATP III, 2001), the International Diabetes Federation (IDF, 2005), the Joint Interim Statement (JIS, 2009), and the All-Russian Research Society of Cardiologists (ARRSC, 2009) were used to detect MS. According to the ARRSC criteria, MS was recorded if a waist circumference (WC) was >80 cm for women and >94 cm for men in conjunction with 2 of the following criteria: a blood pressure ≥130/85 mm Hg, triglycerides (TG) ≥1.7 mmol/l, high-density lipoprotein (HDL) cholesterol <1.0 mmol/l for men and <1.2 mmol/l for women, low-density lipoprotein (LDL) cholesterol >3.0 mmol/l, and plasma glucose level ≥6.1 mmol/l. RESULTS:According to the 2009 ARRSC criteria, the prevalence of abdominal obesity, hypertension, hypertriglyceridemia, HDL hypocholestrolemia, LDL hypercholesterolemia, and high plasma glucose level was 42.6, 33.5, 17.5, 24.3, 64.8, and 29%, respectively. The prevalence of MS in 25-45-year-old Novosibirsk people was 17% (19.9% in men and 14.5% in women) according to the 2001 NCEP-ATP III, 27% (29.5% in men and 24.5% in women) according to the 2005 IDF criteria, 30% (35.8% in men and 25% in women) according to the 2009 JIS criteria, and 29.3% (33.2% in men and 26% in women) according to the 2009 ARRSC criteria, this was higher among men than women. There was an increase in the prevalence of MS with age. CONCLUSION:The highest prevalence of MS was 30 and 29.3% when using the 2009 JIS and the 2009 ARRSC criteria, respectively. Whatever the criterion was used, MS was more frequently recorded in men than women. :Цель исследования. Изучить распространенность метаболического синдрома (МС) и его компонентов в популяции 25-45 лет Новосибирска. Материалы и методы. На базе НИИТПМ в течение 2013-2015 гг. проведено одномоментное популяционное обследование населения одного из типичных районов Новосибирска. В исследование включили 346 мужчин и 408 женщин. Для выявления МС использовали критерии NCEP ATP III (2001), IDF (2005), JIS (2009), ВНОК (2009). Согласно критериям ВНОК (2009) МС регистрировался при окружности талии (ОТ) >80 см у женщин и >94 см у мужчин в сочетании с двумя из следующих критериев: АД ≥130/85 мм рт.ст., триглицериды (ТГ) ≥1,7 ммоль/л, холестерин (ХС) липопротеинов высокой плотности (ЛПВП) <1,0 ммоль/л у мужчин и <1,2 ммоль/л у женщин, ХС липопротеинов низкой плотности (ЛПНП) >3,0 ммоль/л, гипергликемия плазмы ≥6,1 ммоль/л. Результаты. Согласно критериям ВНОК (2009) распространенность абдоминального ожирения составила 42,6%, артериальной гипертонии 33,5%, гипертриглицеридемии 17,5%, гипо-ХС ЛПВП 24,3% , гипер-ХС ЛПНП 64,8%, гипергликемии плазмы крови 29%. Распространенность МС у лиц 25-45 лет Новосибирска составила по критериям NCEP АTP III (2001) 17% (19,9% у мужчин и 14,5% у женщин), по критериям IDF (2005) - 27% (29,5% у мужчин и 24,5% у женщин), по критериям JIS (2009) - 30% (35,8% у мужчин и 25% у женщин), по критериям ВНОК (2009) - 29,3% (33,2% у мужчин, 26% у женщин), больше среди мужчин, чем среди женщин, отмечено увеличение распространенности МС с возрастом. Заключение. Наибольшая распространенность МС достигнута при использовании критериев JIS (2009) и ВНОК (2009) -30 и 29,3% соответственно. Независимо от использованного критерия МС чаще регистрировался у мужчин, чем у женщин. :Цель исследования. Изучить распространенность метаболического синдрома (МС) и его компонентов в популяции 25—45 лет Новосибирска. Материалы и методы. На базе НИИТПМ в течение 2013—2015 гг. проведено одномоментное популяционное обследование населения одного из типичных районов Новосибирска. В исследование включили 346 мужчин и 408 женщин. Для выявления МС использовали критерии NCEP ATP III (2001), IDF (2005), JIS (2009), ВНОК (2009). Согласно критериям ВНОК (2009) МС регистрировался при окружности талии (ОТ) >80 см у женщин и >94 см у мужчин в сочетании с двумя из следующих критериев: АД ≥130/85 мм рт.ст., триглицериды (ТГ) ≥1,7 ммоль/л, холестерин (ХС) липопротеинов высокой плотности (ЛПВП) <1,0 ммоль/л у мужчин и <1,2 ммоль/л у женщин, ХС липопротеинов низкой плотности (ЛПНП) >3,0 ммоль/л, гипергликемия плазмы ≥6,1 ммоль/л. Результаты. Согласно критериям ВНОК (2009) распространенность абдоминального ожирения составила 42,6%, артериальной гипертонии 33,5%, гипертриглицеридемии 17,5%, гипо-ХС ЛПВП 24,3% , гипер-ХС ЛПНП 64,8%, гипергликемии плазмы крови 29%. Распространенность МС у лиц 25—45 лет Новосибирска составила по критериям NCEP АTP III (2001) 17% (19,9% у мужчин и 14,5% у женщин), по критериям IDF (2005) — 27% (29,5% у мужчин и 24,5% у женщин), по критериям JIS (2009) — 30% (35,8% у мужчин и 25% у женщин), по критериям ВНОК (2009) — 29,3% (33,2% у мужчин, 26% у женщин), больше среди мужчин, чем среди женщин, отмечено увеличение распространенности МС с возрастом. Заключение. Наибольшая распространенность МС достигнута при использовании критериев JIS (2009) и ВНОК (2009) —30 и 29,3% соответственно. Независимо от использованного критерия МС чаще регистрировался у мужчин, чем у женщин.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Voevoda MI,Kovalkova NA,Ragino YI,Travnikova NY,Denisova DVdoi
10.17116/terarkh2016881051-56subject
Has Abstractpub_date
2016-01-01 00:00:00pages
51-56issue
10eissn
0040-3660issn
2309-5342journal_volume
88pub_type
杂志文章abstract:AIM:To study causes and sequelae of intradialysis hypotension (IH) in patients with terminal renal failure (TRF). MATERIAL AND METHODS:Forty one patients with TRF on chronic hemodialysis (CH) were divided into two groups. The study group consisted of 24 patients with episodes of IH. Seventeen patients of the control g...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:AIM:To determine the time course of changes in the blood levels of antibodies (Ab) to complement component C1q (a-C1q) in patients with systemic lupus erythematosus (SLE) during rituximab (RTM) therapy and the association with organ injuries in SLE. SUBJECTS AND METHODS:The study involved 41 patients (3 men and 38 wom...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:AIM:To study the urinary excretion of the molecular factors regulating angiogenesis, such as vascular endothelial growth factor type A (VEGF-A), thrombospondin 1 (THBS1), and angiopoietin 2 (ANGPT2), versus that of the urinary markers of renal injury and fibrogenesis, such as neutrophil gelatinase-associated lipocalin ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh201587675-82
更新日期:2015-01-01 00:00:00
abstract:AIM:to investigate time course of changes in the adrenoreactivity (AR) of erythrocyte membranes (EM) after radiofrequency ablation of the synaptic nerves of the renal arteries (RA) in patients with resistant hypertension (RH) and to assess whether this indicator can be used for the early evaluation of the efficiency of...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:10.17116/terarkh201688810-13
更新日期:2016-01-01 00:00:00
abstract::The authors hold that perfection of local therapeutic service in present-day situation when insurance principles are introduced in medical care may be achieved through design of medico-economic standards of guaranteed minimum of medical aid for each citizen of Russian Federation. This approach allows accurate estimati...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:AIM:To investigate effects of trimetazidine and perindopril on myocardial function and metabolism in patients with cardiac failure after myocardial infarction. MATERIAL AND METHODS:A comparative study was mode of the effects of 6-month therapy with perindopril, trimetazidine alone and in combination on clinical sympto...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-01-01 00:00:00
abstract::Diphtheria morbidity among adult population of Moscow is growing. The tests of different modes and schemes of heterogeneous antidiphtheria serum administration have found out that the highest efficacy of serotherapy was achieved with a single intravenous dose. Another treatment of diphtheria is hemosorption. Widely us...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The results of intracoronary thrombolytic therapy with avelysine given to 21 patients with acute myocardial infarction are described. Intracoronary thrombolysis was performed on the average 5 h and 30 min after myocardial infarction onset. Recanalization of the coronary artery was attained in 16 patients, with no leth...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Basing on computer processing of 126 primary clinical and laboratory parameters obtained from 92 patients with myelodysplasia and using multifactorial regression analysis, the authors have developed prognostic models of life span and probability of transformation into acute leukemia. The model of life span enabled rec...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Virological and immunological studies on 53 patients with chronic obstructive bronchitis at the clinical stage of fading exacerbation were conducted. A high percentage of active viral infection (43%), persistence of viruses (25%) and virus-specific components (ribonucleoprotein in influenza) in the cells of brush biop...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:AIM:To determine clinical efficiency and tolerance of paxil (paroxetin) in the treatment of panic disorders. MATERIAL AND METHODS:An open, non-comparative 7 week study entered 60 patients (mean age 36.6 +/- 3.22 years) with panic disorders and agoraphobias with panic disorders. Paroxetin was given in a single daily do...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2000-01-01 00:00:00
abstract::The data obtained in a prospective study made it possible, using Markov's analysis, to assess different forms of coronary heart disease (CHD) of long duration and to elaborate an unsophisticated scale for estimating individual risk of death from that disease. The Markov's analysis demonstrated a high enough probabilit...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The paper presents a case history of multiple myeloma in a female patient. Its diagnosis was established only 10 years after the onset of the disease, which results in severe invalidity (she was treated with calcium preparations in accordance with the diagnosis of generalized osteoporosis. Persistent therapy with calc...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:AIM:To specify circulatory disorders in the bed of common carotid artery (CCA) in hypertensive patients and these disorders influence on psychovegetative and hemodynamic disturbances. MATERIAL AND METHODS:Ultrasonic dopplerography of the region of common carotid artery, ECG, examinations of central hemodynamics, veget...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::As many as 139 patients with dilated cardiomyopathy were examined for the effect of the clinical, ECG, x-ray, phono-, echo- and angiocardiographic indicators and heart catheterization data on the disease outcomes for 3 years after the examination. Risk factors of an unfavorable prediction were distinguished. They incl...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:AIM:Assessment of NO-synthase (NOS) activity in bronchial asthma (BA) basing on cytochemical identification and quantitation of NADPN-diaphorase. MATERIALS AND METHODS:Operative samples from 12 BA patients and biopsies from 8 patients free of bronchial inflammation or obstruction. Experimental data on control and BA r...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Variants of renal damage in sarcoidosis demonstrate the diversity of clinical manifestations common to this systemic disease and serve distinctive reference points in the choice of the treatment policy. A well-defined relationship between hypercalciuria associated with sarcoidosis and risk of calcium nephropathy devel...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Clinical patterns of tuberculous meningitis have been analyzed for 32 admissions to the bacterial meningitis department of the 2nd Moscow Infection Hospital in 1983-1991. Early diagnosis of tuberculous meningitis caused great difficulties because of rare cases of tuberculous history, atypical symptoms (an acute onset,...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:AIM:To evaluate the effect of sitagliptin in combination with metformin on glucose toxicity and lipotoxicity in patients with type 2 diabetes mellitus. SUBJECTS AND METHODS:. Eighty-two overweight and dyslipidemic patients (mean age 55.3 +/- 9.1 years) who had not achieved the goal levels of glycated hemoglobin (HbA1c...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2014-01-01 00:00:00
abstract::Altogether 136 patients with thyrotoxicosis complicated by atrial fibrillation were treated. After drug treatment alone and strumectomy if indicated, over two-thirds of the patients showed sinus rhythm recovery after the attainment of euthyrosis even before institution of the treatment with antiarrhythmic drugs. It is...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract:AIM:To evaluate the modifying effect of physical activity on the association of ADRB3, CLOCK, FABP2, FTO, PPARA, PPARD, PPARG, PPARGC1A, SHBG, UCP2 and UCP3 gene polymorphisms with body mass index (BMI), body fat mass, and risk of obesity. SUBJECTS AND METHODS:The investigation enrolled 582 students and 215 athletes w...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:AIM:To study prognostic significance of individual rehabilitation of patients with pace-maker with account for leading cardiac syndromes. MATERIALS AND METHODS:375 patients with artificial pace-maker were treated in a cardiological hospital for cardiac failure, blood hypertension, angina pectoris, cardiac arrhythmias....
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Based on clinico-endoscopic, x-ray, immunological and immunohistochemical studies the authors demonstrate the role of disorders in the components of humoral and cellular immunity in the development of intestinal inflammation and amyloidosis in patients with periodical disease. Circulatory disorders, congestive hyperem...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Major advances in pharmacology of the 21st century include the development of a new class of drugs, which are low-molecular, chemically synthesized molecules (the so-called "small molecules"), the point of application of which is Janus kinase (Janus kinase, JAK) involved in intracellular cytokine signaling. The review...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:10.26442/00403660.2019.02.000155
更新日期:2019-03-18 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-01-01 00:00:00
abstract::The prevalence of risk factors (RF) to develop cardiovascular disorders alone and in combination has been studied in males aged 20-54 differing by occupation and education. They lived in various cities of CIS and Baltic States. It was established that RF alone and in combination are common among the male population. T...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,多中心研究
doi:
更新日期:1993-01-01 00:00:00
abstract::Ten cases of the pronounced acute nephritic syndrome among patients aged 61 to 82 years are analyzed. In 3 cases, which eventuated in lethal outcome, the diagnosis of nephritis was confirmed morphologically. The features of the course, clinical picture and differential diagnosis of acute nephritides in elderly and sen...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::A study was made of the rate of HLA system antigens in 75 patients with different clinical versions and immuno-pathological manifestations of systemic lupus erythematosus (SLE). A total of 350 normal subjects comprised the control group. During SLE, a high rate of DNW3, B8 and AI antigens was revealed. Associative rel...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Prospects of introduction of personification medicine principles into clinical nephrology are discussed with a special emphasis on prognosis of the course of chronic kidney diseases and response of the latter to pathogenetic therapy. ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:AIM:To assess the role of angiogenic factors (vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in interstitial lung diseases (ILD), such as fibrosing alveolitis, sarcoidosis. SUBJECTS AND METHODS:The blood levels of endothelial dysfunction and neoangiogenesis markers (ET-1 and VEGF) were investigated ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00