Abstract:
:Infectious diseases caused by bacterial pathogens pose a major concern to public health and, thus, greater attention must be given to providing insightful knowledge on host-pathogen interactions. There are several theories addressing the dynamics of complex mechanisms of host-pathogen interactions. The availability of an ample number of universally accepted model systems, including vertebrates, invertebrates, and mammalian cells, provides in-depth transcriptomics data to evaluate these complex mechanisms during host-pathogen interactions. Recent model system based proteomic studies have addressed the issues related to human diseases by establishing the protein profile of model animals that closely resemble the environment. As a result, model system based proteomics has been widely accepted as a powerful and effective approach to understand the highly complex host-pathogen interfaces at their protein levels. This review offers a snapshot of the contributions of selective model systems on host-bacterial pathogen interactions through proteomic approaches.
journal_name
Mol Biosystjournal_title
Molecular bioSystemsauthors
Kamaladevi A,Marudhupandiyan S,Balamurugan Kdoi
10.1039/c7mb00372bsubject
Has Abstractpub_date
2017-11-21 00:00:00pages
2489-2497issue
12eissn
1742-206Xissn
1742-2051journal_volume
13pub_type
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