Developmental origins of infant stress reactivity profiles: A multi-system approach.

Abstract:

BACKGROUND:This study tested the hypothesis that maternal physiological and psychological variables during pregnancy discriminate between theoretically informed infant stress reactivity profiles. METHODS:The sample comprised 254 women and their infants. Maternal mood, salivary cortisol, respiratory sinus arrhythmia (RSA), and salivary α-amylase (sAA) were assessed at 15 and 32 weeks gestational age. Infant salivary cortisol, RSA, and sAA reactivity were assessed in response to a structured laboratory frustration task at 6 months of age. Infant responses were used to classify them into stress reactivity profiles using three different classification schemes: hypothalamic-pituitary-adrenal (HPA)-axis, autonomic, and multi-system. Discriminant function analyses evaluated the prenatal variables that best discriminated infant reactivity profiles within each classification scheme. RESULTS:Maternal stress biomarkers, along with self-reported psychological distress during pregnancy, discriminated between infant stress reactivity profiles. CONCLUSIONS:These results suggest that maternal psychological and physiological states during pregnancy have broad effects on the development of the infant stress response systems. © 2016 Wiley Periodicals, Inc. Dev Psychobiol 58: 578-599, 2016.

journal_name

Dev Psychobiol

authors

Rash JA,Thomas JC,Campbell TS,Letourneau N,Granger DA,Giesbrecht GF,APrON Study Team.

doi

10.1002/dev.21403

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

578-99

issue

5

eissn

0012-1630

issn

1098-2302

journal_volume

58

pub_type

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