Introduction to the Analysis of Survival Data in the Presence of Competing Risks.

abstract：BACKGROUND:Unfractionated heparin has been the primary anticoagulant therapy for percutaneous coronary intervention for >20 years. Despite the availability of rapid "point of care" testing, little clinical data defining the optimal level of anticoagulation are available. Furthermore, recent reports have advocated the u...

journal_title：Circulation

authors： Chew DP,Bhatt DL,Lincoff AM,Moliterno DJ,Brener SJ,Wolski KE,Topol EJ

更新日期：2001-02-20 00:00:00

abstract：BACKGROUND:There has been increasing interest in the development of agents that utilize endogenous adenosine to exert their actions. We tested the hypothesis that substances that either potentiate the activity (allosteric enhancers) or increase the interstitial concentration (inhibitors of metabolism) of endogenous ade...

journal_title：Circulation

authors： Dennis DM,Raatikainen MJ,Martens JR,Belardinelli L

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:The availability of selective antagonists for angiotensin II receptors has focused interest on the gene expression of angiotensin II-receptor subtypes in the human heart. METHODS AND RESULTS:We analyzed expression of the AT1 and AT2 subtypes of the angiotensin II receptor in ventricular myocardium taken fro...

journal_title：Circulation

authors： Haywood GA,Gullestad L,Katsuya T,Hutchinson HG,Pratt RE,Horiuchi M,Fowler MB

更新日期：1997-03-04 00:00:00

abstract：BACKGROUND:Out-of-hospital cardiac arrest (OHCA) is a major public health problem. We sought to describe changes in 1-month survival after OHCA in patients given cardiopulmonary resuscitation (CPR) during the last 14 years in Sweden. METHODS AND RESULTS:All patients experiencing OHCA in whom CPR was attempted between ...

journal_title：Circulation

authors： Hollenberg J,Herlitz J,Lindqvist J,Riva G,Bohm K,Rosenqvist M,Svensson L

更新日期：2008-07-22 00:00:00

abstract：BACKGROUND:Increased diastolic chamber stiffness (increased DCS) during angina (demand ischemia) has been postulated to be generated by increased diastolic myocyte calcium concentration. METHODS AND RESULTS:We reproduced demand ischemia in isolated isovolumically contracting red-cell-perfused rabbit hearts by imposing...

journal_title：Circulation

authors： Varma N,Eberli FR,Apstein CS

更新日期：2000-05-09 00:00:00

abstract：BACKGROUND:Cardiac Na/K-ATPase (NKA) regulates intracellular Na ([Na](i)), which in turn affects intracellular Ca and thus contractility via Na/Ca exchange. Recent evidence shows that phosphorylation of the NKA-associated small transmembrane protein phospholemman (PLM) mediates beta-adrenergic-induced NKA stimulation. ...

journal_title：Circulation

authors： Despa S,Tucker AL,Bers DM

更新日期：2008-04-08 00:00:00

abstract：BACKGROUND:Apolipoprotein E (apoE) has long been known to play an important role in the clearance of plasma lipoproteins. More recently, a direct role for apoE in delaying atherogenesis has been proposed. Macrophage production of apoE in the artery wall has been demonstrated to provide protection against atheroscleroti...

journal_title：Circulation

authors： Hasty AH,Linton MF,Brandt SJ,Babaev VR,Gleaves LA,Fazio S

更新日期：1999-05-18 00:00:00

abstract：:From January 1968 to June 1975 tricuspid regurgitation was encountered in 238 patients of a total of 1074 patients undergoing operations on the mitral valve. During this time tricuspid annuloplasty (TA) was performed in 137 patients and the tricuspid valve was replaced (TVR) in 101 patients. Comparison of hospital mor...

journal_title：Circulation

authors： Reed GE,Boyd AD,Spencer FC,Engelman RM,Isom OW,Cunningham JN Jr

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Adrenomedullin (AM) is a vasodilating peptide involved in the regulation of circulatory homeostasis and in the pathophysiology of certain cardiovascular diseases. To determine the extent to which chronic AM overproduction affects circulatory physiology under normal and pathological conditions, we used a prep...

journal_title：Circulation

authors： Shindo T,Kurihara H,Maemura K,Kurihara Y,Kuwaki T,Izumida T,Minamino N,Ju KH,Morita H,Oh-hashi Y,Kumada M,Kangawa K,Nagai R,Yazaki Y

更新日期：2000-05-16 00:00:00

abstract：BACKGROUND:Abnormalities of arterial pulse and limb growth after retrograde femoral arterial catheterization have been well documented. However, the magnitude of such complications after transfemoral artery balloon dilatation has not been thoroughly investigated. This study sought to evaluate the prevalence of these ab...

journal_title：Circulation

authors： Lee HY,Reddy SC,Rao PS

更新日期：1997-02-18 00:00:00

abstract：BACKGROUND:Clinical depression is associated with an increased risk for mortality in patients with a recent myocardial infarction (MI). Reduced heart rate variability (HRV) has been suggested as a possible explanation for this association. The purpose of this study was to determine if depression is associated with redu...

journal_title：Circulation

authors： Carney RM,Blumenthal JA,Stein PK,Watkins L,Catellier D,Berkman LF,Czajkowski SM,O'Connor C,Stone PH,Freedland KE

更新日期：2001-10-23 00:00:00

abstract：BACKGROUND:Lipoprotein(a) [Lp(a)] may play a causal role in atherosclerosis. PCSK9 (proprotein convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce plasma Lp(a) concentration. However, the relationship between Lp(a) levels, PCSK9 inhibition, and cardiovascular risk reduction remains undefin...

journal_title：Circulation

authors： O'Donoghue ML,Fazio S,Giugliano RP,Stroes ESG,Kanevsky E,Gouni-Berthold I,Im K,Lira Pineda A,Wasserman SM,Češka R,Ezhov MV,Jukema JW,Jensen HK,Tokgözoğlu SL,Mach F,Huber K,Sever PS,Keech AC,Pedersen TR,Sabatine MS

更新日期：2019-03-19 00:00:00

abstract：:The effectiveness of intra-aortic balloon pumping in augmenting ventricular performance during acute myocardial ischemic syndromes was determined by noninvasive multigated cardiac blood pool imaging. Nine patients with unstable angina refractory to medical therapy and nine patients with acute myocardial infarction com...

journal_title：Circulation

authors： Nichols AB,Pohost GM,Gold HK,Leinbach RC,Beller GA,McKusick KA,Strauss HW,Buckley MJ

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Aortic valve-preserving procedures have resulted in excellent outcomes in selected patients, particularly those with normal aortic valve leaflets and dilated aortic roots. However, several congenital heart lesions are associated with abnormal aortic valve leaflets. The long-term results of aortic valve repai...

journal_title：Circulation

authors： Rao V,Van Arsdell GS,David TE,Azakie A,Williams WG

更新日期：2000-11-07 00:00:00

abstract：BACKGROUND:The atrioventricular (AV) node is insensitive to changes in extracellular potassium concentration, [K+]o, because of the absence of the inward rectifier potassium current (IK1). However, we propose that in the presence of adenosine, elevated [K+]o should increase the adenosine-activated inward rectifier pota...

journal_title：Circulation

authors： Martynyuk AE,Morey TE,Belardinelli L,Dennis DM

更新日期：1999-01-19 00:00:00

abstract：:Correlates of high-density lipoprotein (HDL) cholesterol levels were studied in 4756 white males and females ages 20-59 years examined during a population survey conducted by 10 North American Lipid Research Clinics. Multivariable analysis was used to assess the relation of social, demographic, physical and behavioral...

journal_title：Circulation

authors： Heiss G,Johnson NJ,Reiland S,Davis CE,Tyroler HA

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Increased plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have been identified as predictors of cardiac dysfunction and prognosis in congestive heart failure and ischemic heart disease. In severe sepsis patients, however, no information is available yet about the prognos...

journal_title：Circulation

authors： Brueckmann M,Huhle G,Lang S,Haase KK,Bertsch T,Weiss C,Kaden JJ,Putensen C,Borggrefe M,Hoffmann U

更新日期：2005-07-26 00:00:00

abstract：BACKGROUND:Treatment of aortocaval fistulae (ACFs) by open surgery is known to be a high-risk procedure. In this experimental study, we developed a percutaneous model of ACF to test a new nonsurgical method of treatment of ACF using endovascular stent grafts. METHODS AND RESULTS:An ACF was created percutaneously in ei...

journal_title：Circulation

authors： Boudghène F,Sapoval M,Bonneau M,Bigot JM

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Many members of families with inherited long-QT (LQT) syndrome have mutations in HERG, a gene encoding a cardiac potassium channel that is modulated by extracellular potassium. We hypothesized that an increase in serum potassium would normalize repolarization in these patients. METHODS AND RESULTS:We studie...

journal_title：Circulation

authors： Compton SJ,Lux RL,Ramsey MR,Strelich KR,Sanguinetti MC,Green LS,Keating MT,Mason JW

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:It has recently been shown that mitochondrial aldehyde dehydrogenase 2 (mtALDH) catalyzes the formation of 1,2-glyceryl dinitrate and nitrite from nitroglycerin (glyceryl trinitrate [GTN]) within mitochondria, leading to production of cGMP and vasorelaxation. However, whether this mechanism operates in the s...

journal_title：Circulation

authors： Zhang J,Chen Z,Cobb FR,Stamler JS

更新日期：2004-08-10 00:00:00

abstract：BACKGROUND:C-kit is a receptor tyrosine kinase family member expressed in hematopoietic stem cells. C-kit is also transiently expressed in cardiomyocyte precursors during development and in a rare cell population in the normal adult heart. In the present study, the cardiomyogenic potential of c-kit(+) cells isolated fr...

journal_title：Circulation

authors： Zaruba MM,Soonpaa M,Reuter S,Field LJ

更新日期：2010-05-11 00:00:00

abstract：:Continuous-wave Doppler echocardiography was used to estimate pulmonary artery pressures by measuring pulmonary regurgitant flow velocity in 21 patients with pulmonary hypertension (mean pulmonary artery pressure greater than or equal to 20 mm Hg) and 24 patients without pulmonary hypertension. The pulmonary regurgita...

journal_title：Circulation

authors： Masuyama T,Kodama K,Kitabatake A,Sato H,Nanto S,Inoue M

更新日期：1986-09-01 00:00:00

abstract：:We assessed the reversibility of functional and morphological changes of arterialized vein segments by returning them to the venous circulation. Thirteen dogs underwent right carotid and femoral veno-arterial grafting. After 12 weeks, veno-arterial grafts were removed for contractility (norepinephrine [NE] and 5-hydro...

journal_title：Circulation

authors： Fann JI,Sokoloff MH,Sarris GE,Yun KL,Kosek JC,Miller DC

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Exercise stimulates the vascular response in pathological conditions, including ischemia; however, the molecular mechanisms by which exercise improves the impaired hypoxia-induced factor (HIF)-1 alpha-mediated response to hypoxia associated with aging are poorly understood. Here, we report that swimming trai...

journal_title：Circulation

authors： Cheng XW,Kuzuya M,Kim W,Song H,Hu L,Inoue A,Nakamura K,Di Q,Sasaki T,Tsuzuki M,Shi GP,Okumura K,Murohara T

更新日期：2010-08-17 00:00:00

abstract：:Knowledge of the potential gradient field created by defibrillation electrodes is important for the understanding and improvement of defibrillation. To obtain this knowledge by direct measurements, potentials were recorded from 60 epicardial, eight septal, and 36 right ventricular transmural electrodes in six open-che...

journal_title：Circulation

authors： Chen PS,Wolf PD,Claydon FJ,Dixon EG,Vidaillet HJ Jr,Danieley ND,Pilkington TC,Ideker RE

更新日期：1986-09-01 00:00:00

abstract：:The importance of pulmonary artery size and the value of a standardized pulmonary artery index (PAI) in predicting outcome after Fontan's repair have previously been reported and questioned. We retrospectively reviewed 29 patients undergoing modified Fontan repair at The Children's Hospital of Philadelphia to examine ...

journal_title：Circulation

authors： Bridges ND,Farrell PE Jr,Pigott JD 3rd,Norwood WI,Chin AJ

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Cerebral protection during surgery for acute aortic dissection type A relies on hypothermic circulatory arrest, either alone or in conjunction with cerebral perfusion. METHODS AND RESULTS:The perioperative and intraoperative conditions of 1558 patients submitted from 44 cardiac surgery centers in German-spe...

journal_title：Circulation

authors： Krüger T,Weigang E,Hoffmann I,Blettner M,Aebert H,GERAADA Investigators.

更新日期：2011-07-26 00:00:00

abstract：BACKGROUND:The mainstay of treatment for atrial fibrillation (AF) remains pharmacological; however, catheter ablation has increasingly been used over the last decade. The relative merits of each strategy have not been extensively studied. METHODS AND RESULTS:We conducted a randomized multicenter comparison of these 2 ...

journal_title：Circulation

authors： Jaïs P,Cauchemez B,Macle L,Daoud E,Khairy P,Subbiah R,Hocini M,Extramiana F,Sacher F,Bordachar P,Klein G,Weerasooriya R,Clémenty J,Haïssaguerre M

更新日期：2008-12-09 00:00:00

abstract：BACKGROUND:Despite early recanalization of an occluded infarct artery, reperfusion at the level of the microcirculation may remain impaired owing to a process of microvascular reperfusion injury. METHODS AND RESULTS:Microvascular reperfusion injury was studied in 91 patients with acute myocardial infarction (AMI) by e...

journal_title：Circulation

authors： Claeys MJ,Bosmans J,Veenstra L,Jorens P,De RaedtH,Vrints CJ

更新日期：1999-04-20 00:00:00

abstract：BACKGROUND:Poststroke angiogenesis contributes to long-term recovery after stroke. Signal transducer and activator of transcription-3 (Stat3) is a key regulator for various inflammatory signals and angiogenesis. It was the aim of this study to determine its function in poststroke outcome. METHODS AND RESULTS:We genera...

journal_title：Circulation

authors： Hoffmann CJ,Harms U,Rex A,Szulzewsky F,Wolf SA,Grittner U,Lättig-Tünnemann G,Sendtner M,Kettenmann H,Dirnagl U,Endres M,Harms C

更新日期：2015-05-19 00:00:00